Patents by Inventor Redford B. Williams

Redford B. Williams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLYMORPHISM IN TRYPTOPHAN HYDROXYLASE-2 CONTROLS BRAIN SEROTONIN SYNTHESIS
    Publication number: 20100256116
    Abstract: A method of screening a subject for a serotonergic neurotransmission dysregulation disorder comprises detecting the presence or absence of an Tph2 mutation in the subject; and then determining that the subject is at increased risk of a serotonergic neurotransmission dysregulation disorder due to the presence or absence of the Tph2 mutation.
    Type: Application
    Filed: July 28, 2009
    Publication date: October 7, 2010
    Inventors: Marc G. Caron, Xiaodong Zhang, Martin Beaulieu, Raul R. Gainetdinov, Tatiana D. Sotnikova, Ranga R. Krishnan, David A. Schwartz, Redford B. Williams, Lauranell Burch
  • Polymorphism in tryptophan hydroxylase-2 controls brain serotonin synthesis
    Patent number: 7585627
    Abstract: A method of screening a subject for a serotonergic neurotransmission dysregulation disorder comprises detecting the presence or absence of an Tph2 mutation in the subject; and then determining that the subject is at increased risk of a serotonergic neurotransmission dysregulation disorder due to the presence or absence of the Tph2 mutation.
    Type: Grant
    Filed: May 20, 2005
    Date of Patent: September 8, 2009
    Assignee: Duke University
    Inventors: Marc G. Caron, Xiaodong Zhang, Martin Beaulieu, Raul R. Gainetdinov, Tatiana D. Sotnikova, Ranga R. Krishnan, David A. Schwartz, Lauranell Burch, Redford B. Williams
  • Use of polymorphism of the serotonin transporter gene promoter as a predictor of disease risk
    Patent number: 7371522
    Abstract: The present invention provides a method of screening subjects for disease risk. The method comprises determining the serotonin transporter gene promoter genotype of a subject. The serotonin transporter gene promoter genotype is used to indicate whether or not the subject is at increased risk of disease. The method is particularly adapted to screening for risk of disease in response to stress, and accordingly can be used to indicate interventions that manage stress, and hence reduce disease risk, in susceptible or higher-risk individuals.
    Type: Grant
    Filed: July 23, 2003
    Date of Patent: May 13, 2008
    Assignee: Duke University
    Inventor: Redford B. Williams, Jr.
  • Use of polymorphism of the serotonin transporter gene promoter as a predictor of disease risk
    Publication number: 20040126786
    Abstract: The present invention provides a method of screening subjects for disease risk. The method comprises determining the serotonin transporter gene promoter genotype of a subject. The serotonin transporter gene promoter genotype is used to indicate whether or not the subject is at increased risk of disease. The method is particularly adapted to screening for risk of disease in response to stress, and accordingly can be used to indicate interventions that manage stress, and hence reduce disease risk, in susceptible or higher-risk individuals.
    Type: Application
    Filed: July 23, 2003
    Publication date: July 1, 2004
    Inventor: Redford B. Williams