Patents by Inventor Reem Haider

Reem Haider has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Efficient method of synthesizing combretastatin A-4 prodrugs
    Patent number: 6743937
    Abstract: Methods of synthesizing a phosphate ester of combretastatin A-4 and trans-isomers thereof in which combretastatin A-4 is reacted with dibenzylphosphite in the presence of carbon tetrabromide, or with 2,2,2-trichloroethyl phosphorodichloridate, to form a phosphate ester of combretastatin A-4 with protecting groups thereon.
    Type: Grant
    Filed: July 17, 2001
    Date of Patent: June 1, 2004
    Assignee: OxiGene, Inc.
    Inventors: Faye Seyedi, Jonathan Gale, Reem Haider, John Hoare, Amy Baldwin
  • Efficient method of synthesizing combretastatin A-4 prodrugs
    Publication number: 20020119951
    Abstract: Methods of synthesizing a phosphate ester of combretastat-in A-4 and trans-isomers thereof in which combretastatin A-4 is reacted with dibenzylphosphite in the presence of carbon tetrabromide, or with 2,2,2-trichloroethyl phosphorodichloridate, to form a phosphate ester of combretastatin A-4 with protecting groups thereon.
    Type: Application
    Filed: July 17, 2001
    Publication date: August 29, 2002
    Inventors: Faye Seyedi, Jonathan Gale, Reem Haider, John Hoare, Amy Baldwin
  • Synthesis of 3-aryl-1-indanamines
    Patent number: 6268535
    Abstract: The present invention is a method of preparing a 3-aryl-1-indanamine represented by structural formula I: and physiologically acceptable salts thereof. In structure I, phenyl ring A can be unsubstituted or substituted with 1-4 substitutents. R1 is an aromatic group which can be substituted or unsubstituted. R2 and R3 are each, independently, hydrogen, an aliphantic group, a substituted aliphatic group, an aromatic group, a substituted aromatic group, an aralkyl group, or a substituted aralkyl group. Alternatively, R2 and R3, taken together with the nitrogen substitutent on the indan ring, form a non-aromatic ring system having 1-2 heteroatoms.
    Type: Grant
    Filed: January 7, 1999
    Date of Patent: July 31, 2001
    Assignee: Pharm-Eco Laboratories, Inc.
    Inventors: Adel M. Moussa, Reem Haider, Heather Taft, Jurjus Jurayj, Weiheng Wang, HaeSuk Suh
  • Method for making substituted indoles
    Patent number: 6133453
    Abstract: Disclosed is a method of preparing a compound represented by the following structural formula: ##STR1## and physiological salts thereof. R.sup.1 is --H, an aliphatic group, a substituted aliphatic group, an aryl group or a substituted aryl group.R.sup.2 is a substituted or unsubstituted 2-hydroxy-1-ethyl group.Ring A is a substituted or unsubstituted aryl group.Ring B is substituted or unsubstituted at position two.
    Type: Grant
    Filed: May 11, 1999
    Date of Patent: October 17, 2000
    Assignee: Pharm-Eco Laboratories, Inc.
    Inventors: Robert Stevenson, Milind P. Sant, Reem Haider, Ahmed Hilmy, Emile Al-Farhan