Patents by Inventor Reema Panjwani

Reema Panjwani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating cancer using cell based therapies
    Patent number: 11859208
    Abstract: This disclosure relates to compositions and methods of reversing senescence in T cells by interrupting vasoactive intestinal peptide (VIP) signaling and/or inhibiting phosphatidylinositol-3-kinase (PI3 kinase) inhibitor signaling and uses in managing cancer and chronic viral infections. In certain embodiments, the disclosure contemplates methods of reversing T cell senescence by mixing T cell in vitro with an agent that prevents VIP from interacting with VIP receptors and/or a PI3 Kinase inhibitor. In certain embodiments, the disclosure contemplates the expansion of senescent T cells by mixing with a PI3 kinase inhibitor, an agent that block VIP and VIP receptor signaling, a VIP degrading enzyme, and combinations thereof.
    Type: Grant
    Filed: April 5, 2017
    Date of Patent: January 2, 2024
    Assignee: Emory University
    Inventors: Edmund Waller, Anna Morris, Christopher Petersen, Jian-Ming Li, Reema Panjwani, Jingxia Li
  • Methods of Treating Cancer and Infectious Diseases Using Cell Based Therapies
    Publication number: 20190144825
    Abstract: This disclosure relates to compositions and methods of reversing senescence in T cells by interrupting vasoactive intestinal peptide (VIP) signaling and/or inhibiting phosphatidylinositol-3-kinase (PI3 kinase) inhibitor signaling and uses in managing cancer and chronic viral infections. In certain embodiments, the disclosure contemplates methods of reversing T cell senescence by mixing T cell in vitro with an agent that prevents VIP from interacting with VIP receptors and/or a PI3 Kinase inhibitor. In certain embodiments, the disclosure contemplates the expansion of senescent T cells by mixing with a PI3 kinase inhibitor, an agent that block VIP and VIP receptor signaling, a VIP degrading enzyme, and combinations thereof.
    Type: Application
    Filed: April 5, 2017
    Publication date: May 16, 2019
    Inventors: Edmund Waller, Anna Morris, Christopher Petersen, Jian-Ming Li, Reema Panjwani, Jingxia Li