Patents by Inventor Reeta Prusty Rao

Reeta Prusty Rao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antifungal agents and uses thereof
    Patent number: 10350217
    Abstract: Antimicrobial agents, compositions that include the agent(s) and use(s) thereof are provided. Also disclosed are screening assays for identifying antimicrobial agents.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: July 16, 2019
    Assignees: University of Massachusetts, Worcester Polytechnic Institute
    Inventors: Paul Kaufman, Jessica Lopes Da Rosa-Spiegler, Reeta Prusty Rao, Ahmed Fazly
  • ANTIFUNGAL AGENTS AND USES THEREOF
    Publication number: 20170224703
    Abstract: Antimicrobial agents, compositions that include the agent(s) and use(s) thereof are provided. Also disclosed are screening assays for identifying antimicrobial agents.
    Type: Application
    Filed: April 7, 2017
    Publication date: August 10, 2017
    Inventors: Paul KAUFMAN, Jessica Lopes DA ROSA-SPIEGLER, Reeta Prusty RAO, Ahmed FAZLY
  • Antifungal agents and uses thereof
    Patent number: 9648880
    Abstract: Antimicrobial agents, compositions that include the agent(s) and use(s) thereof are provided. Also disclosed are screening assays for identifying antimicrobial agents.
    Type: Grant
    Filed: September 4, 2013
    Date of Patent: May 16, 2017
    Assignees: University of Massachusetts, Worcester Polytechnic Institute
    Inventors: Paul Kaufman, Jessica Lopes Da Rosa-Spiegler, Reeta Prusty Rao, Ahmed Fazly
  • IDENTIFYING ANTIFUNGAL AGENTS THAT INHIBIT IAA OR A YAP FAMILY MEMBER
    Publication number: 20150168403
    Abstract: The present invention relates to methods of screening for antifungal agents by identifying agents that bind to or otherwise inhibit indole-3-acetic acid (IAA) or that bind to or otherwise inhibit the expression or activity of a protein within the Yap family or a gene encoding a protein within the Yap family.
    Type: Application
    Filed: December 18, 2014
    Publication date: June 18, 2015
    Inventor: Reeta Prusty Rao
  • ANTIFUNGAL AGENTS AND USES THEREOF
    Publication number: 20140142107
    Abstract: Antimicrobial agents, compositions that include the agent(s) and use(s) thereof are provided. Also disclosed are screening assays for identifying antimicrobial agents.
    Type: Application
    Filed: September 4, 2013
    Publication date: May 22, 2014
    Applicant: University of Massachusetts
    Inventors: Paul Kaufman, Jessica Lopes Da Rosa-Spiegler, Reeta Prusty Rao, Ahmed Fazly
  • COMPOSITIONS AND METHODS FOR IDENTIFYING VIRULENCE FACTORS AND ANTI-FUNGAL AGENTS
    Publication number: 20140041064
    Abstract: The present invention is based on the discovery of a two- or three-organism model system that can be used to identify virulence factors involved in fungal infection and to screen for agents that attenuate the activity of those factors. The system includes a model eukaryote, the nematode, Caenorhabditis elegans, and one or more species of Candida, a fungal pathogen that infects humans, e.g., Candida albicans, C. dubliniensis, C. krusei, C. tropicalis, C. parapsilosis, or C. glabrata. The system also includes a food source for the C. elegans; the food source can be a live or attenuated bacterium, e.g., Escherichia coli.
    Type: Application
    Filed: March 7, 2012
    Publication date: February 6, 2014
    Applicant: WORCESTER POLYTECHNIC INSTITUTE
    Inventor: Reeta Prusty Rao
  • Targets, including Yap1, for antifungal drug discovery and therapy
    Patent number: 8541197
    Abstract: The present invention is based on the discovery of a two organism model system that can be used to identify virulence factors. The system is also useful in the process of drug delivery. More specifically, we have established valid fungal infection in caenorhabditis elegans with an invading pathogen, the yeast Saccharomyces cerevisiae. Because both species are genetic model organisms, the assay can be used to identify host and virulence factors involved in such interactions.
    Type: Grant
    Filed: December 10, 2007
    Date of Patent: September 24, 2013
    Assignee: Worcester Polytechnic Institute
    Inventors: Reeta Prusty Rao, Samuel Michael Politz
  • INDENTIFYING ANTIFUNGAL AGENTS THAT INHIBIT IAA OR A YAP FAMILY
    Publication number: 20130130305
    Abstract: The present invention relates to methods of screening for antifungal agents by identifying agents that bind to or otherwise inhibit indole-3-acetic acid (IAA) or that bind to or otherwise inhibit the expression or activity of a protein within the Yap family or a gene encoding a protein within the Yap family.
    Type: Application
    Filed: May 17, 2011
    Publication date: May 23, 2013
    Inventor: Reeta Prusty Rao
  • TARGETS, INCLUDING YAP1, FOR ANTIFUNGAL DRUG DISCOVERY AND THERAPY
    Publication number: 20110033442
    Abstract: The present invention is based on the discovery of a two organism model system that can be used to identify virulence factors. The system is also useful in the process of drug delivery. More specifically, we have established valid fungal infection in caenorhabditis elegans with an invading pathogen, the yeast Saccharomyces cerevisiae. Because both species are genetic model organisms, the assay can be used to identify host and virulence factors involved in such interactions.
    Type: Application
    Filed: December 10, 2007
    Publication date: February 10, 2011
    Applicant: Worcester Polytechnic Institute
    Inventors: Reeta Prusty Rao, Samuel Michael Politz