Patents by Inventor Reevis S. Alphin

Reevis S. Alphin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of using 2-alkoxy-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamide-N-oxides to control emesis caused by anticancer drugs
    Patent number: 4722834
    Abstract: A method of controlling emesis caused by anticancer drugs with 2-alkoxy-N-(1-azabicyclo[2.2.2]oct-3-yl) benzamide-N-oxides having the formula: ##STR1## wherein R.sub.1 is loweralkyl, and R.sub.2 is selected from the group consisting of hydrogen, halo, 4,5-benzo, methylsulfonyl, loweralkoxy or Am and n is 1 or 2, and the pharmaceutically acceptable acid addition salts thereof is disclosed.
    Type: Grant
    Filed: March 5, 1986
    Date of Patent: February 2, 1988
    Assignee: A. H. Robins Company, Incorporated
    Inventors: Lina C. Teng, Stephen C. Bearekman, Lennox B. Turnbull, Reevis S. Alphin, William L. Smith
  • 2-alkoxy-N-(1-azabicyclo(2.2.2)oct-3-yl) benzamides and thiobenzamides in a method for alleviating emesis caused by non-platinum anticancer drugs
    Patent number: 4717563
    Abstract: A method of controlling emesis caused by non-platinum anti-cancer drugs with 2-alkoxy-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamides and thiobenzamides having the formula ##STR1## wherein X is oxygen or sulfur; R.sub.1 is loweralkyl; and R.sub.2 is selected from the group consisting of hydrogen, halo, 4,5-benzo, methylsulfonyl, loweralkoxy or Am and n is 1 or 2, and the pharmaceutically acceptable acid addition salts thereof is disclosed.
    Type: Grant
    Filed: March 5, 1986
    Date of Patent: January 5, 1988
    Assignee: A. H. Robins Company, Inc.
    Inventors: Reevis S. Alphin, William L. Smith, Harry R. Munson, Jr., Robert F. Boswell
  • 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds
    Patent number: 4343804
    Abstract: A method of reducing gastric acidity and treating peptic ulcers and pharmaceutical compositions therefor with certain 4-amino-3-quinolinecarboxylic acids and esters are disclosed.
    Type: Grant
    Filed: March 4, 1980
    Date of Patent: August 10, 1982
    Assignee: A. H. Robins Company, Inc.
    Inventors: Harry R. Munson, Jr., Reevis S. Alphin
  • Method of increasing rate of gastric emptying with pyrrolidinylbenzamides
    Patent number: 4109005
    Abstract: Pyrrolidinyl benzamides represented by the formula: ##STR1## wherein R is methyl or cycloalkyl having 3 to 12 carbon atoms; R.sup.1 is hydrogen or methyl and the pharmaceutically acceptable salts thereof are disclosed in methods which increase the rate of gastric emptying in mammals.
    Type: Grant
    Filed: May 11, 1977
    Date of Patent: August 22, 1978
    Assignee: A. H. Robins Company, Inc.
    Inventors: Carl D. Lunsford, Reevis S. Alphin