Patents by Inventor Refael Barkan

Refael Barkan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • S-ALKYLISOTHIOURONIUM DERIVATIVES FOR TREATING UTERINE HYPERCONTRACTILITY DISORDERS
    Publication number: 20200360313
    Abstract: The present invention relates to methods for treating uterine hypercontractility disorders. in particular, the present invention relates to methods for treating abnormal uterine bleeding and dysmenorrhea comprising administering to women suffering from such disorders a pharmaceutical composition comprising an S-alkylisothiouronium derivative.
    Type: Application
    Filed: July 30, 2020
    Publication date: November 19, 2020
    Inventors: Refael BARKAN, Victor GHICAVII
  • COMPOSITIONS OF S-ALKYLISOTHIOURONIUM DERIVATIVES FOR TREATING UPPER RESPIRATORY CONGESTION
    Publication number: 20100311691
    Abstract: The present invention provides intranasal pharmaceutical compositions comprising an S-alkylisothiouronium derivative and methods of treating or alleviating upper respiratory and oral-pharyngeal congestions by pharmaceutical compositions comprising the S-alkylisothiouronium derivative.
    Type: Application
    Filed: November 6, 2008
    Publication date: December 9, 2010
    Inventors: Refael Barkan, Victor Ghicavii
  • S-ALKYLISOTHIOURONIUM DERIVATIVES FOR TREATING ABNORMAL UTERINE BLEEDING DISORDERS
    Publication number: 20100305210
    Abstract: The present invention relates to methods for treating uterine hypercontractility disorders. In particular, the present invention relates to methods for treating abnormal uterine bleeding and dysmenorrhea comprising administering to women suffering from such disorders a pharmaceutical composition comprising an S-alkylisothiouronium derivative.
    Type: Application
    Filed: November 6, 2008
    Publication date: December 2, 2010
    Applicant: Barkan-Farma S.R.L.
    Inventors: Refael Barkan, Victor Ghicavii
  • TASTE MASKED PHARMACEUTICAL COMPOSITIONS OF S-ALKYLISOTHIOURONIUM DERIVATIVES
    Publication number: 20100285127
    Abstract: The present invention relates to taste masked compositions of S-alkylisothiouronium derivatives, including, but not limited to, S-ethylisothiouronium diethylphosphate, in the form of a coated oral tablet having a desirable dissolution profile.
    Type: Application
    Filed: June 13, 2007
    Publication date: November 11, 2010
    Inventors: Refael Barkan, David Coffin-Beach, Victor Ghicavii
  • S-ALKYLISOTHIOURONIUM DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISEASES
    Publication number: 20090186854
    Abstract: The present invention relates to uses of S-alkylisothiouronium derivatives for treating inflammation. In particular, the present invention provides extended release pharmaceutical dosage forms of S-alkylisothiouronium derivatives and methods of use thereof for the treatment of various inflammatory diseases or conditions.
    Type: Application
    Filed: March 25, 2007
    Publication date: July 23, 2009
    Applicant: Meditor Pharmaceuticals Ltd.
    Inventors: Refael Barkan, Victor Ghicavii
  • ASSESSMENT OF DIAMOND COLOR
    Publication number: 20090182520
    Abstract: Disclosed are methods and devices for assessing the colors of diamonds. In embodiments, the color of finished diamonds cut from a given rough diamond is assessed by analyzing the effect on light interacting with the rough diamond to give a reasonable (that is to say commercially significant) assessment of the color quality of the finished diamond.
    Type: Application
    Filed: December 12, 2006
    Publication date: July 16, 2009
    Inventors: Yoav Luxembourg, Erez Avrahamov, Refael Barkan, Yehuda Shekel, Ira Hartman
  • PREVENTION OF HYPOTENSION AND STABILIZATION OF BLOOD PRESSURE IN HEMODIALYSIS PATIENTS
    Publication number: 20090018206
    Abstract: The present invention relates to the use of S-alkylisothiouronium derivatives, including S-ethylisothiouronium diethylphosphate, for stabilizing blood pressure in hemodialysis patients. The compositions of the invention are effective in preventing hypotension in hemodialysis patients.
    Type: Application
    Filed: September 6, 2006
    Publication date: January 15, 2009
    Inventors: Refael Barkan, Alexander Mirimsky, Ze've Katzir, Victor Ghicavii