Patents by Inventor Regan Memmott

Regan Memmott has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for regulating transcription by targeting quadruplex DNA
    Patent number: 7405041
    Abstract: Among the different intrastrand quadruplex structures that can arise from duplex DNA, it has been discovered that the nucleotide sequences (GGA)4 (SEQ ID NO: 1) and (GGA)3GG (SEQ ID NO: 2) form biologically significant quadruplex structures. Thus, provided herein are methods for identifying molecules that modulate the biological activity of quadruplex DNA comprising the nucleotide sequence (GGA)4 (SEQ ID NO: 1) or the nucleotide sequence (GGA)3GG (SEQ ID NO: 2), and specifically, methods for identifying molecules that bind such quadruplexes. Also provided herein are methods for modulating the biological activity of a biologically significant native quadruplex DNA with a molecule identified by the methods described herein.
    Type: Grant
    Filed: August 20, 2003
    Date of Patent: July 29, 2008
    Assignee: Arizona Board of Regents on behalf of the University of Arizona
    Inventors: Scot W. Ebbinghaus, Laurence H. Hurley, Adam Siddiqui-Jain, Regan Memmott
  • Methods for regulating transcription by targeting quadruplex DNA
    Publication number: 20040171022
    Abstract: Among the different intrastrand quadruplex structures that can arise from duplex DNA, it has been discovered that the nucleotide sequences (GGA)4 and (GGA)3GG form biologically significant quadruplex structures. Thus, provided herein are methods for identifying molecules that modulate the biological activity of quadruplex DNA comprising the nucleotide sequence (GGA)4 or the nucleotide sequence (GGA)3GG, and specifically, methods for identifying molecules that bind such quadruplexes. Also provided herein are methods for modulating the biological activity of a biologically significant native quadruplex DNA with a molecule identified by the methods described herein.
    Type: Application
    Filed: August 20, 2003
    Publication date: September 2, 2004
    Inventors: Scot W. Ebbinghaus, Laurence H. Hurley, Adam Siddiqui-Jain, Regan Memmott