Patents by Inventor Regina Graul

Regina Graul has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRTH2 MODULATORS AND PREPARATION THEREOF
    Publication number: 20140187795
    Abstract: The present invention relates to processes and intermediates for the preparation of compounds useful as CRTH2 antagonists. Compounds prepared by the processes of the invention are of Formula (AI), (All) and Compound (I).
    Type: Application
    Filed: June 17, 2011
    Publication date: July 3, 2014
    Applicant: Ironwood Pharmaceuticals, Inc.
    Inventors: James Jia, Regina Graul, Wayne C Schairer, Vishnu Karnati, Ray Forslund
  • CRTH2 modulators
    Patent number: 8674115
    Abstract: Modulators of CRTH2, particularly antagonists of CRTH2, that are useful for treating various disorders, including asthma and respiratory disorders are disclosed.
    Type: Grant
    Filed: December 16, 2010
    Date of Patent: March 18, 2014
    Assignee: Ironwood Pharmaceuticals, Inc.
    Inventors: Ara Mermerian, Bo Peng, Colleen Hudson, Charles Kim, Joel Moore, Jason Rohde, Kevin Sprott, Regina Graul, Takashi Nakai, James Jia, Wilmin Bartolini
  • CRTH2 MODULATORS
    Publication number: 20130259830
    Abstract: Modulators of CRTH2, particularly antagonists of CRTH2, that are useful for treating various disorders, including asthma and respiratory disorders are disclosed.
    Type: Application
    Filed: June 24, 2011
    Publication date: October 3, 2013
    Applicant: Ironwood Pharmaceuticals, Inc.
    Inventors: Timothy Barden, Colleen Hudson, James Jia, Charles Kim, Regina Graul, Ara Mermerian, Joel Moore, Kevin Sprott, Yueh-tyng Chien
  • CRTH2 MODULATORS
    Publication number: 20130216552
    Abstract: Modulators of CRTH2, particularly antagonists of CRTH2, that are useful for treating various disorders, including asthma and respiratory disorders are disclosed herein.
    Type: Application
    Filed: June 24, 2011
    Publication date: August 22, 2013
    Applicant: Ironwood Pharmaceuticals, Inc.
    Inventors: Takashi Nakai, James Jia, Jason Rohde, Regina Graul, Ara Mermerian
  • Selenophene and Selenazole Carboxylic Acid Derivatives
    Publication number: 20120149743
    Abstract: Derivatives of selenophene and selenazole heterocycles are disclosed. The compounds are useful as inhibitors of D-amino acid oxidase (DAO) and in the treatment of neurodegenerative and psychiatric diseases and disorders.
    Type: Application
    Filed: June 2, 2009
    Publication date: June 14, 2012
    Applicant: Ironwood Pharmaceuticals, Inc
    Inventor: Regina Graul
  • CRTH2 MODULATORS
    Publication number: 20110312945
    Abstract: Modulators of CRTH2, particularly antagonists of CRTH2, that are useful for treating various disorders, including asthma and respiratory disorders are disclosed.
    Type: Application
    Filed: October 1, 2009
    Publication date: December 22, 2011
    Inventors: James Jia, Ara Mermerian, Charles Kim, Regina Graul, Joel Moore
  • Pyrrolopyridine Carboxylic Acid Derivatives
    Publication number: 20110312938
    Abstract: Disclosed are compounds and pharmaceutically acceptable salts of Formula (I) wherein R1, R2, R3, and RN are as defined herein. Compounds of Formula (I) are useful in the prevention and/or treatment of neurological and psychiatric disorder, or the like. Also disclosed are pharmaceutical compositions comprising compounds of the disclosure and methods of treating the aforementioned conditions using such compounds.
    Type: Application
    Filed: June 30, 2009
    Publication date: December 22, 2011
    Applicant: Ironwood Pharmaceuticals, Inc.
    Inventors: Regina Graul, John Jeffrey Talley, Ara Mermerian
  • CRTH2 MODULATORS
    Publication number: 20110311483
    Abstract: Compounds of Formulae I-1 to I-9 are disclosed, which are modulators of CRTH2, particularly antagonists of CRTH2, that are useful for treating various disorders, including asthma and respiratory disorders.
    Type: Application
    Filed: March 29, 2011
    Publication date: December 22, 2011
    Applicant: IRONWOOD PHARMACEUTICALS, INC.
    Inventors: James JIA, Regina GRAUL, Bo PENG, Colleen HUDSON, Joel MOORE, Ara MERMERIAN
  • Selenophene and Selenazole Carboxylic Acid Derivatives
    Publication number: 20110275683
    Abstract: Derivatives of selenophene and selenazole heterocycles are disclosed. The compounds are useful as inhibitors of D-amino acid oxidase (DAO) and in the treatment of neurodegenerative and psychiatric diseases and disorders.
    Type: Application
    Filed: June 2, 2009
    Publication date: November 10, 2011
    Applicant: Ironwood Pharmaceuticals, Inc
    Inventor: Regina Graul
  • CRTH2 MODULATORS
    Publication number: 20110150834
    Abstract: Modulators of CRTH2, particularly antagonists of CRTH2, that are useful for treating various disorders, including asthma and respiratory disorders are disclosed.
    Type: Application
    Filed: December 16, 2010
    Publication date: June 23, 2011
    Inventors: Ara MERMERIAN, Bo Peng, Colleen Hudson, Charles Kim, Joel Moore, Jason Rohde, Kevin Sprott, Regina Graul, Takashi Nakai, James Jia, Wilmin Bartolini