Abstract: Rapid antimicrobial susceptibility testing (AST) can be an integral tool to mitigate the unnecessary use of powerful and broad spectrum antibiotics that leads to the proliferation of multi-drug resistant bacteria. Methods and systems for a sensor platform composed of surface enhanced Raman scattering (SERS) sensors with surfaces having molecular control of nano architecture and surface chemistry and machine learning processes for analyzing SERS data, are described to detect metabolic profiles from susceptible antibiotic resistant bacteria strains for rapid AST.

Abstract: Nanoarchitectures comprised of subwavelength metal nanosphere oligomers with uniform narrow gap spacings for plasmonic and metamaterial devices are described, as well as methods of fabrication thereof, a biosensor system based thereon, and methods of detection of pathogenic or other organisms (e.g., bacteria) using the same.

Abstract: Nanoarchitectures comprised of subwavelength metal nanosphere oligomers with uniform narrow gap spacings for plasmonic and metamaterial devices are described, as well as methods of fabrication thereof, a biosensor system based thereon, and methods of detection of pathogenic or other organisms (e.g., bacteria) using the same.

Abstract: A method for generating layered structures is disclosed. The method comprises reacting an azide-functionalized material with an alkyne-functionalized material, one of which can be a nanoparticle or a microparticle and the other can be a substrate or another nanoparticle or microparticle. The method also includes generating layered structures having multiple layers which can be built up in multiple azide-alkyne reaction steps.