Abstract: A non-contact system for sorting monodisperse water-in-oil emulsion droplets in a microfluidic device based on the droplet's contents and their interaction with an applied electromagnetic field or by identification and sorting.

Abstract: A system for analyzing a sample including providing a microchannel flow channel; associating the sample with magnetic nanoparticles or magnetic polystyrene-coated beads; moving the sample with said magnetic nanoparticles or magnetic polystyrene-coated beads in the microchannel flow channel; holding the sample with the magnetic nanoparticles or magnetic polystyrene-coated beads in a magnetic trap in the microchannel flow channel; and analyzing the sample obtaining an enhanced analysis signal. An apparatus for analysis of a sample includes magnetic particles connected to the sample, a microchip, a flow channel in the microchip, a source of carrier fluid connected to the flow channel for moving the sample in the flow channel, an electromagnet trap connected to the flow line for selectively magnetically trapping the sample and the magnetic particles, and an analyzer for analyzing the sample.

Abstract: An apparatus for passive sorting of microdroplets including a main flow channel, a flow stream of microdroplets in the main flow channel wherein the microdroplets have substantially the same diameter and wherein the flow stream of microdroplets includes first microdroplets having a first degree of stiffness and second microdroplets having a second degree of stiffness wherein the second degree of stiffness is different than the first degree of stiffness. A second flow channel is connected to the main flow channel for the second microdroplets having a second degree of stiffness. A separator separates the second microdroplets having a second degree of stiffness from the first microdroplets and directs the second microdroplets having a second degree of stiffness into the second flow channel.

Abstract: An apparatus for penetrating a cover over a multi-well sample plate containing at least one individual sample well includes a cutting head, a cutter extending from the cutting head, and a robot. The cutting head is connected to the robot wherein the robot moves the cutting head and cutter so that the cutter penetrates the cover over the multi-well sample plate providing access to the individual sample well. When the cutting head is moved downward the foil is pierced by the cutter that splits, opens, and folds the foil inward toward the well. The well is then open for sample aspiration but has been protected from cross contamination.

Abstract: A system for analyzing a sample including providing a microchannel flow channel; associating the sample with magnetic nanoparticles or magnetic polystyrene-coated beads; moving the sample with said magnetic nanoparticles or magnetic polystyrene-coated beads in the microchannel flow channel; holding the sample with the magnetic nanoparticles or magnetic polystyrene-coated beads in a magnetic trap in the microchannel flow channel; and analyzing the sample obtaining an enhanced analysis signal. An apparatus for analysis of a sample includes magnetic particles connected to the sample, a microchip, a flow channel in the microchip, a source of carrier fluid connected to the flow channel for moving the sample in the flow channel, an electromagnet trap connected to the flow line for selectively magnetically trapping the sample and the magnetic particles, and an analyzer for analyzing the sample.

Abstract: A method and system is presented for introducing functional polynucleotides into a target polynucleotide using transposons.

Abstract: A method and apparatus for relating a device name to a physical location of a device (202) on a network is provided. The network may be a serial loop network, for example a Fibre Channel Arbitrated Loop network. The network includes a plurality of devices (202) on or connected to the network (201) and a control device (205) with control over at least one of the devices (202). Each device (202) has a check output (204) independent of the network (201) with connection means (206) to a control device (205). The method includes the step of sending a device name from the check output (204) of a device (202) to the control device (205). The check output (204) of a device (202) is also connected to an external indication means for indicating the failure of the device (202).

Abstract: A system for fast DNA sequencing by amplification of genetic material within microreactors, denaturing, demulsifying, and then sequencing the material, while retaining it in a PCR/sequencing zone by a magnetic field. One embodiment includes sequencing nucleic acids on a microchip that includes a microchannel flow channel in the microchip. The nucleic acids are isolated and hybridized to magnetic nanoparticles or to magnetic polystyrene-coated beads. Microreactor droplets are formed in the microchannel flow channel. The microreactor droplets containing the nucleic acids and the magnetic nanoparticles are retained in a magnetic trap in the microchannel flow channel and sequenced.

Abstract: A micro-electro-mechanical system for heating a sample including a substrate, a micro-channel flow channel in the substrate, a carrier fluid within the micro-channel flow channel for moving the sample in the micro-channel flow channel, and a microwave source that directs microwaves onto the sample in the micro-channel flow channel for heating the sample. The carrier fluid and the substrate are made of materials that are not appreciably heated by the microwaves. The microwave source includes conductive traces or strips and a microwave power source connected to the conductive traces or strips.

Abstract: A logic arrangement, method and computer program for reducing incidence of errors in a redundant path system during a process of attachment of a device to a running subsystem, comprises a control component for encapsulating the process of attachment of a device to a running subsystem; a disabling component for disabling a path interface; a testing component for testing for the presence of a usable data path across at least one further path interface; and an enabling component for enabling the at least one further path interface to accept communication with the device responsive to a positive outcome from the testing component; wherein the control component is adapted to permit operation after attachment of the device only if full redundancy is retained. A re-enabling component may re-enable any path interface or further path interface.

Abstract: An apparatus for chip-based sorting, amplification, detection, and identification of a sample having a planar substrate. The planar substrate is divided into cells. The cells are arranged on the planar substrate in rows and columns. Electrodes are located in the cells. A micro-reactor maker produces micro-reactors containing the sample. The micro-reactor maker is positioned to deliver the micro-reactors to the planar substrate. A microprocessor is connected to the electrodes for manipulating the micro-reactors on the planar substrate. A detector is positioned to interrogate the sample contained in the micro-reactors.

Abstract: A system of heating a sample on a microchip includes the steps of providing a microchannel flow channel in the microchip; positioning the sample within the microchannel flow channel, providing a laser that directs a laser beam onto the sample for heating the sample; providing the microchannel flow channel with a wall section that receives the laser beam and enables the laser beam to pass through wall section of the microchannel flow channel without being appreciably heated by the laser beam; and providing a carrier fluid in the microchannel flow channel that moves the sample in the microchannel flow channel wherein the carrier fluid is not appreciably heated by the laser beam.

Abstract: A system for monodispersed microdroplet generation and trapping including providing a flow channel in a microchip; producing microdroplets in the flow channel, the microdroplets movable in the flow channel; providing carrier fluid in the flow channel using a pump or pressure source; controlling movement of the microdroplets in the flow channel and trapping the microdroplets in a desired location in the flow channel. The system includes a microchip; a flow channel in the microchip; a droplet maker that generates microdroplets, the droplet maker connected to the flow channel; a carrier fluid in the flow channel, the carrier fluid introduced to the flow channel by a source of carrier fluid, the source of carrier fluid including a pump or pressure source; a valve connected to the carrier fluid that controls flow of the carrier fluid and enables trapping of the microdroplets.

Abstract: Apparatus for heating a sample includes a microchip; a microchannel flow channel in the microchip, the microchannel flow channel containing the sample; a microwave source that directs microwaves onto the sample for heating the sample; a wall section of the microchannel flow channel that receives the microwaves and enables the microwaves to pass through wall section of the microchannel flow channel, the wall section the microchannel flow channel being made of a material that is not appreciably heated by the microwaves; a carrier fluid within the microchannel flow channel for moving the sample in the microchannel flow channel, the carrier fluid being made of a material that is not appreciably heated by the microwaves; wherein the microwaves pass through wall section of the microchannel flow channel and heat the sample.

Abstract: A portable apparatus for thermal cycling a material to be thermal cycled includes a portable microfluidic-compatible platform, a microfluidic heat exchanger carried by the portable microfluidic-compatible platform; a porous medium in the microfluidic heat exchanger; a microfluidic thermal cycling chamber containing the material to be thermal cycled, the microfluidic thermal cycling chamber operatively connected to the microfluidic heat exchanger; a working fluid at first temperature, a first system for transmitting the working fluid at first temperature to the microfluidic heat exchanger; a working fluid at a second temperature, a second system for transmitting the working fluid at second temperature to the microfluidic heat exchanger; a pump for flowing the working fluid at the first temperature from the first system to the microfluidic heat exchanger and through the porous medium; and flowing the working fluid at the second temperature from the second system to the heat exchanger and through the porous medi

Abstract: A system for thermal cycling a material to be thermal cycled including a microfluidic heat exchanger; a porous medium in the microfluidic heat exchanger; a microfluidic thermal cycling chamber containing the material to be thermal cycled, the microfluidic thermal cycling chamber operatively connected to the microfluidic heat exchanger; a working fluid at first temperature; a first system for transmitting the working fluid at first temperature to the microfluidic heat exchanger; a working fluid at a second temperature, a second system for transmitting the working fluid at second temperature to the microfluidic heat exchanger; a pump for flowing the working fluid at the first temperature from the first system to the microfluidic heat exchanger and through the porous medium; and flowing the working fluid at the second temperature from the second system to the heat exchanger and through the porous medium.

Abstract: A method and apparatus for recovery from faults in a loop network (500) is provided. The loop network (500) has a plurality of ports (520, 530, 532, 534) serially connected with means for bypassing the ports (520, 530, 532, 534) from the loop network (500). A control device (522, 524) is provided with bypass control over at least one of the ports (530, 532, 534). A host means (502) sends a command to the control device (522, 524) at regular intervals and the control device (522, 524) has a counter which restarts a time period at the receipt of each command. If the time period expires, the control device (522, 524) activates the means for bypassing all the ports (530, 532, 534) under its control. The loop network (500) may have two loops (516, 518) with at least some of the ports (520, 530, 532, 534) common to both loops (516, 518).

Abstract: A method and apparatus for relating a device name to a physical location of a device (202) on a network is provided. The network may be a serial loop network, for example a Fibre Channel Arbitrated Loop network. The network includes a plurality of devices (202) on or connected to the network (201) and a control device (205) with control over at least one of the devices (202). Each device (202) has a check output (204) independent of the network (201) with connection means (206) to a control device (205). The method includes the step of sending a device name from the check output (204) of a device (202) to the control device (205). The check output (204) of a device (202) is also connected to an external indication means for indicating the failure of the device (202).

Abstract: A method and apparatus for relating a device name to a physical location of a device (202) on a network is provided. The network may be a serial loop network, for example a Fibre Channel Arbitrated Loop network. The network includes a plurality of devices (202) on or connected to the network (201) and a control device (205) with control over at least one of the devices (202). Each device (202) has a check output (204) independent of the network (201) with connection means (206) to a control device (205). The method includes the step of sending a device name from the check output (204) of a device (202) to the control device (205). The check output (204) of a device (202) is also connected to an external indication means for indicating the failure of the device (202).

Abstract: A method and apparatus for detection of a port name in a loop network is provided, particularly a loop network in the form of a Fibre Channel Arbitrated Loop (FC-AL). The loop network (100) has a plurality of devices (120) each device (120) having at least one port (211, 212) on the loop network (100). The method includes determining which ports (211, 212) are populated with devices (120) for which the unique port name (WWPN) is not known. The populated ports are then all bypassed and a mode is entered on the loop network (100) in which idle frames are transmitted around the loop network (100). One port is un-bypassed at a time and the port name from the un-bypassed port is received and recorded. The port name is received from the un-bypassed port in a Loop Initialisation Select Master (LISM) frame transmitted by the un-bypassed port.