Patents by Inventor Reginald C.X. Brys

Reginald C.X. Brys has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Adenoviral library assay for E2F regulatory genes and methods and compositions for screening compounds
    Publication number: 20030166167
    Abstract: Abstract The invention relates to the field of molecular genetics and medicine. In particular the present invention relates to the field of functional genomics. The present invention provides the methods and means for the identification of nucleic acids and the polypeptides encoded by these nucleic acids that have a function related to the E2F pathway, which were isolated in a high-throughput screening assay using the E2F transcription factor activity as a read-out. The identified compounds are suitable drug-targets to treat human diseases.
    Type: Application
    Filed: May 1, 2002
    Publication date: September 4, 2003
    Inventors: Helmuth van Es, Rene Bernards, Godefridus A.M. Michiels, Reginald C.X. Brys, Peter H. M. Tomme
  • Adenoviral library assay for E2F regulatory genes and methods and compositions for screening compounds
    Publication number: 20030059794
    Abstract: The invention relates to the field of molecular genetics and medicine. In particular the present invention relates to the field of functional genomics. The present invention provides the methods and means for the identification of nucleic acids and the polypeptides encoded by these nucleic acids that have a function related to the E2F pathway, which were isolated in a high-throughput screening assay using the E2F transcription factor activity as a read-out. The identified compounds are suitable drug-targets to treat human diseases.
    Type: Application
    Filed: March 5, 2002
    Publication date: March 27, 2003
    Inventors: Ronald Vogels, Abraham Bout, Helmuth van Es, Govert Schouten, Rene Bernards, Godefridus A.M. Michiels, Reginald C.X. Brys, Peter Herwig Maria Tomme