Abstract: Methods of improving recombinant protein titer and cell titer in cell culture using cell culture media having reduced impurities are provided, and well as cell culture media having reduced impurities that can used for the production of a recombinant protein and cells with improved titer. The cell culture media having reduced impurities comprises a HEPES buffer, and the reduced impurities are HEPES related impurities. In certain aspects, methods and media improve protein titer, cell growth, and/or viable cell density.

Abstract: Provided are techniques that may include a disposable magnetic cell isolation holder having one or more passages that accommodate a magnetic retention material to facilitate magnetic cell isolation without adjustment of magnetic field parameters between isolation procedures using different magnetic particle sizes. When the magnetic cell isolation holder is coupled to a magnetic field generator, a first passage corresponding to a smaller particle size is positioned in a magnetic field where the magnetic field characteristics are different relative to a second passage, of a second holder or in the same holder, for use with another bead size.

Abstract: Provided are techniques that may include a disposable magnetic cell isolation holder having one or more passages that accommodate a magnetic retention material to facilitate magnetic cell isolation without adjustment of magnetic field parameters between isolation procedures using different magnetic particle sizes. When the magnetic cell isolation holder is coupled to a magnetic field generator, a first passage corresponding to a smaller particle size is positioned in a magnetic field where the magnetic field characteristics are different relative to a second passage, of a second holder or in the same holder, for use with another bead size.

Abstract: Provided are techniques that may include a disposable magnetic cell isolation holder having one or more passages that accommodate a magnetic retention material to facilitate magnetic cell isolation without adjustment of magnetic field parameters between isolation procedures using different magnetic particle sizes. When the magnetic cell isolation holder is coupled to a magnetic field generator, a first passage corresponding to a smaller particle size is positioned in a magnetic field where the magnetic field characteristics are different relative to a second passage, of a second holder or in the same holder, for use with another bead size.

Abstract: Provided are techniques that may include a disposable magnetic cell isolation holder having one or more passages that accommodate a magnetic retention material to facilitate magnetic cell isolation without adjustment of magnetic field parameters between isolation procedures using different magnetic particle sizes. When the magnetic cell isolation holder is coupled to a magnetic field generator, a first passage corresponding to a smaller particle size is positioned in a magnetic field where the magnetic field characteristics are different relative to a second passage, of a second holder or in the same holder, for use with another bead size.

Abstract: An instrument stand that is collapsible, portable, and stable. The instrument stand includes a first support and a second support. The first support and the second support each include a wing-shaped body and an instrument-receiving cavity. The wing-shaped body includes a fixed end, a free end, a top edge portion, a bottom edge portion, an inner surface, and an outer surface. The fixed end of the first support is adjacently and hingedly connected to the fixed end of the second support, creating a V-shaped structure. The instrument-receiving cavity receives a held instrument and traverses through the top edge portion. Additionally, the instrument-receiving cavity traverses through the wing-shaped body from the outer surface to the inner surface, adjacent to the free end. The first support and the second support are identical and are mirrored through a sagittal plane to ensure adequate support and stability for the held instrument.

Abstract: A nonwoven composite and a method of making a nonwoven composite including lightly bonding and hydroentangling a continuous filament nonwoven web to improve its integrity and fiber mobility for subsequent processing steps, such as adding a first layer to the continuous filament nonwoven web and hydroentangling the first layer and the continuous filament nonwoven web together.

Abstract: The present invention provides a nonwoven web prepared from multicomponent fibers which are partially split. The partially split multicomponent fibers have at least one component of the multicomponent fiber separated from the remaining components of the multicomponent fiber along a first section of the longitudinal length of the multicomponent fibers. Along a second section of the longitudinal length of the multicomponent fibers the components of the multicomponent fibers remain together as a unitary fiber structure. In addition, part of the second section of the multicomponent fibers is bonded to part of a second section of an adjacent multicomponent fiber.

Abstract: The present invention provides a nonwoven web prepared from multicomponent fibers which are partially split. The partially split multicomponent fibers have at least one component of the multicomponent fiber separated from the remaining components of the multicomponent fiber along a first section of the longitudinal length of the multicomponent fibers. Along a second section of the longitudinal length of the multicomponent fibers the components of the multicomponent fibers remain together as a unitary fiber structure. In addition, part of the second section of the multicomponent fibers is bonded to part of a second section of an adjacent multicomponent fiber.

Abstract: A nonwoven composite and a method of making a nonwoven composite including lightly bonding and hydroentangling a continuous filament nonwoven web to improve its integrity for subsequent processing steps, such as adding a first layer to the continuous filament nonwoven web and hydroentangling the first layer and the continuous filament nonwoven web together.

Abstract: A nonwoven composite and a method of making a nonwoven composite including lightly bonding and hydroentangling a continuous filament nonwoven web to improve its integrity and fiber mobility for subsequent processing steps, such as adding a first layer to the continuous filament nonwoven web and hydroentangling the first layer and the continuous filament nonwoven web together.

Abstract: Agents and methods for qualitative and quantitative analysis a protein complex or protein complexes using isotope-labeled symmetrical bifunctional crosslinkers and mass spectrometry are provided. Targeting moieties, cell permeability moieties, or affinity moieties, may be appended to the bifunctional crosslinkers. The isotope-labeled symmetrical bifunctional crosslinkers may be used in a kit or as a library.

Abstract: A multifunctional device that has a three-part design that will give the user outstanding capabilities. One part that will be mentioned is a one-part system that will be intergraded with a plasma screen or a PLC monitor. The system includes a built-in computer, video processor. The video processor part of the system will have Hyper Thread technology along with MP-3 capabilities. The second part that will be mentioned is a two-part system that will have the previously mentioned functions. This systems base unit is compact and has the ability of a full-scale computer. This unit has a built in video processor that is the control center of the system. This part of the unit has a programmable chip. This part of the system will allow the user to control all incoming and outgoing signals. This unit will allow the user to use many different infotainment devices simultaneously. The third part that will be mentioned is a unit the size of a CD player that fits in a vehicle.

Abstract: The present invention is generally directed to base webs that are creped after a bonding material has been applied to at least one side of the web according to a predetermined pattern. According to the present invention, the bonding material contains a creping adhesive mixed with composite particles. The composite particles generally have a median particle size of less than about 5 microns and a particle size distribution of less than about 10 microns.

Abstract: There is provided a resilient, three dimensional material having fibrous texture and appearance and capable of fluid handling. It consists of a top surface and a bottom surface wherein fiber-like elements typically extend from one surface to the other forming flat to undulating surfaces characterized by a multiplicity of interconnected fluid passageways. Deformed, discontinuous film-like or encapsulated regions connect fiber-like elements and stabilize the material. The material of this invention is unique based on the three principle characteristics which are communicated in this application: 1) ff(?)<0.87, 2) SA/VV<186 cm2/cm3, and 3) caliper<0.150 inches. This material is useful for a number of purposes, such as for use as a liner for personal care products like diapers, absorbent underpants, swim wear, feminine hygiene products, adult incontinence products and the like.

Abstract: The present invention is generally directed to base webs that are creped after a bonding material has been applied to at least one side of the web according to a predetermined pattern. According to the present invention, the bonding material contains a creping adhesive mixed with composite particles. The composite particles generally have a median particle size of less than about 5 microns and a particle size distribution of less than about 10 microns.

Abstract: The present invention is generally directed to base webs that are creped after a bonding material has been applied to at least one side of the web according to a predetermined pattern. According to the present invention, the bonding material contains a creping adhesive mixed with composite particles. The composite particles generally have a median particle size of less than about 5 microns and a particle size distribution of less than about 10 microns.

Abstract: A biaxially extendible, breathable laminate having liquid barrier properties and low retractive force. The laminate includes a nonwoven web neck-stretched in a first direction to impart extendibility of the web in a second direction mutually perpendicular with the first direction, and a film that is extendible in the second direction. The film can be a breathable, microporous film, and can either be an inelastic film stretched to form rugosities in the second direction, or can be made of an extendible polymer that is extendible in the second direction. Using an appropriate elastomeric lamination and/or creping adhesive, the laminate is creped to produce extendibility in the first direction with some retractive force. The biaxial extendible laminate is particularly useful as an outer cover for diapers and other personal care products.

Abstract: The present invention is generally directed to base webs that are creped after a bonding material has been applied to at least one side of the web according to a predetermined pattern. According to the present invention, the bonding material contains a creping adhesive mixed with composite particles. The composite particles generally have a median particle size of less than about 5 microns and a particle size distribution of less than about 10 microns.

Abstract: A biaxially extendible, breathable laminate having liquid barrier properties and low retractive force. The laminate includes a nonwoven web neck-stretched in a first direction to impart extendibility of the web in a second direction mutually perpendicular with the first direction, and a film that is extendible in the second direction. The film can be a breathable, microporous film, and can either be an inelastic film stretched to form rugosities in the second direction, or can be made of an extendible polymer that is extendible in the second direction. Using an appropriate elastomeric lamination and/or creping adhesive, the laminate is creped to produce extendibility in the first direction with some retractive force. The biaxial extendible laminate is particularly useful as an outer cover for diapers and other personal care products.