Patents by Inventor Reham Mostafa El-Meligy

Reham Mostafa El-Meligy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190231841
    Abstract: Cenchrus ciliaris L. as an anticancer agent was obtained by separately extracting the aerial parts of the plant and the root part of the plants. Extractions were performed first in ethanol, and then a portion successively in water, chloroform, and aqueous butanol. All extracts were tested for cytotoxicity against six cancer cell lines. Generally, the root extracts exhibited greater cytotoxicity than the aerial extracts. The highest anticancer effects for both aerial and root extracts were shown against hepatocellular cancer, colorectal cancer, and lung cancer, compared to the other cell lines tested. The chloroform extracts showed greater anticancer effects, both for aerial and root extracts.
    Type: Application
    Filed: January 29, 2018
    Publication date: August 1, 2019
    Inventors: AMANI SHAFEEK AWAAD, NOURAH AHMED AL QURAIN, HAYA FAHD ALKANHAL, REHAM MOSTAFA EL-MELIGY, FATMAH ALI AL-ASAMARY
  • Patent number: 10137162
    Abstract: The gastroprotective extracts of S. oleraceus L. are ethanol extracts (including the initial ethanol extract and serial extractions of the marc in ethanol), which are concentrated at low temperature to obtain a gummy residue that is dissolved in water. Lipoidal compounds are removed from aqueous extracts by filtration, and serial extracts proceeding from the aqueous extracts using chloroform to obtain low polarity phenolic compounds and n-butanol to obtain high polarity compounds and any remaining compounds. These extracts may be used to treat conditions of the stomach and colon including preventing peptic ulcers and treating ulcerative colitis.
    Type: Grant
    Filed: January 26, 2018
    Date of Patent: November 27, 2018
    Assignee: King Saud University
    Inventors: Amani Shafeek Awaad, Shekhah Saud Almoqren, Amal Ahmed Safhi, Yara Mohamed Zain, Reham Mostafa El-Meligy, Fatmah Ali Al-Asamary
  • Patent number: 10098924
    Abstract: The anticancer extracts of Alpinia officinarum Hance are produced by percolation extraction of dried Alpinia officinarum Hance rhizomes in 95% ethanol. The extracts may then be concentrated, suspended in water, filtered, and lyophilized. The resulting anticancer extracts may be used to kill a variety of cancer cells, including lung cancer, colorectal cancer, colon cancer, cervical cancer, and prostate cancer.
    Type: Grant
    Filed: January 23, 2018
    Date of Patent: October 16, 2018
    Assignee: KING SAUD UNIVERSITY
    Inventors: Amani Shafeek Awaad, Menatallah Mohamed Allah, Lara Ayman El-Sawaf, Reham Mostafa El-Meligy, Fatmah Ali Al-Asamary
  • Patent number: 10016425
    Abstract: Anti-ulcerative colitis compounds include quinazoline derivatives having the following structural formula: wherein R is H, OH, or OCH3, R1 is OH or OCH3, and R2 is OCH3 or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: November 3, 2016
    Date of Patent: July 10, 2018
    Assignee: KING SAUD UNIVERSITY
    Inventors: Amani Shafeek Awaad, Ahmed Mahmoud Ahmed Alafify, Reham Mostafa El-Meligy
  • Publication number: 20180117046
    Abstract: Anti-ulcerative colitis compounds include quinazoline derivatives having the following structural formula: wherein R is H, OH, or OCH3, R1 is OH or OCH3, and R2 is OCH3, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: November 3, 2016
    Publication date: May 3, 2018
    Inventors: AMANI SHAFEEK AWAAD, AHMED MAHMOUD AHMED ALAFIFY, REHAM MOSTAFA EL-MELIGY
  • Patent number: 9629885
    Abstract: A method for treating candidiasis includes administering to a human or animal subject in need thereof, a therapeutically effective amount of an anti-candidiasis compound. The anti-candidiasis compound can include 3?-diglucoside-5, 12-28-oic acid. The anti-candidiasis can be isolated from an extract of Petriella setifera or other Petriella species.
    Type: Grant
    Filed: March 8, 2016
    Date of Patent: April 25, 2017
    Assignee: KING SAUD UNIVERSITY
    Inventors: Amani Shafeek Awaad, Mohamed El-Desouky Zain, Reham Mostafa El-Meligy, Nour Khaled Al-Anazi, Monerah Rashed Alothman
  • Patent number: 9598361
    Abstract: An amino substituted acetamide derivative can include a compound having the following general formula: wherein R represents (4-Cyano-4-phenyl)piperidinyl hydrochloride, (4-Hydroxy-4-phenyl)piperidine, (4-chlorophenyl)piperidine hydrochloride, 4-Piperidinopiperidine, 4-(Methoxyphenyl)piperidine, 1-(2,3-xylyl)piperazine monohydrochloride, 4-Aminoquinaldine or anthranilic acid, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: April 12, 2016
    Date of Patent: March 21, 2017
    Assignee: KING SAUD UNIVERSITY
    Inventors: Amani Shafeek Awaad, Ahmed Mahmoud Ahmed Alafeefy, Reham Mostafa El-Meligy