Patents by Inventor Rei Shibata

Rei Shibata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MAGNETIC-FIELD GENERATOR FOR A CELL SHEET
    Publication number: 20230126629
    Abstract: A magnetic-field generator (10) is provided to be used in construction of a cell sheet (12), and include s a magnetic circuit assembly (24) configured to generate a magnetic field for the construction of the cell sheet (12) using magnetic force caused by the magnetic field wherein the magnetic force is substantially transverse to a plane defined by the cell sheet (12), and a power control system (44) configured to generate and control electric power to magnetically charge the magnetic circuit assembly (24) using the electric power.
    Type: Application
    Filed: April 13, 2021
    Publication date: April 27, 2023
    Inventors: Kotaro HIRAYAMA, Hotaka KAYANO, Shota TANOUE, Yuki WATANABE, Toshio KOKURYO, Rei SHIBATA, Akira ITO, Toyoaki MUROHARA
  • Therapeutic application of adiponectin in patients with ventricular fibrillation
    Patent number: 8883732
    Abstract: A therapeutic method for cardiac diseases such as angina, myocardial infarction, arrhythmia (ventricular tachycardia, ventricular fibrillation and atrial fibrillation) is provided. The method is characterized by intracoronary administration of adiponection to mammals.
    Type: Grant
    Filed: March 11, 2013
    Date of Patent: November 11, 2014
    Assignee: National University Corporation Nagoya University
    Inventors: Rei Shibata, Toyoaki Murohara
  • VASCULAR PROGENITOR CELL SHEET DERIVED FROM INDUCED PLURIPOTENT STEM CELLS, AND PRODUCTION METHOD THEREFOR
    Publication number: 20140301988
    Abstract: The present invention addresses the problem of providing a vascular progenitor cell sheet derived from induced pluripotent stem cells, which has the strength to tolerate practical applications and exhibits a high treatment effect. This vascular progenitor cell sheet derived from induced pluripotent stem cells is prepared by performing: (1) a step for preparing magnetically labeled Flk-1 positive cells derived from induced pluripotent stem cells; (2) a step for preparing a mixture of the Flk-1 positive cells and a gel material including type I collagen, laminin, type IV collagen and entactin as active ingredients, and then disseminating the mixture in a culture vessel; (3) a step for drawing the Flk-1 positive cells in the mixture to the culture surface of the culture vessel by application of a magnetic force to form a multi-layered cell layer; and (4) a step for gelling the gel material.
    Type: Application
    Filed: November 7, 2012
    Publication date: October 9, 2014
    Inventors: Toyoaki Murohara, Hiroyuki Honda, Rei Shibata, Masakazu Ishii, Tetsutaro Kito, Hirohiko Suzuki
  • THERAPEUTIC APPLICATION OF ADIPONECTIN IN PATIENTS WITH VENTRICULAR FIBRILLATION
    Publication number: 20130217627
    Abstract: A therapeutic method for cardiac diseases such as angina, myocardial infarction, arrhythmia (ventricular tachycardia, ventricular fibrillation and atrial fibrillation) is provided. The method is characterized by intracoronary administration of adiponection to mammals.
    Type: Application
    Filed: March 11, 2013
    Publication date: August 22, 2013
    Applicant: National University Corporation Nagoya University
    Inventors: Rei SHIBATA, Toyoaki MUROHARA
  • Therapeutic Application of Adiponectin in Patients with Acute Myocardial Infarction
    Publication number: 20120035111
    Abstract: A therapeutic method for cardiac diseases such as angina, myocardial infarction, arrhythmia (ventricular tachycardia, ventricular fibrillation and atrial fibrillation) is provided. The method is characterized by intracoronary administration of adiponection to mammals.
    Type: Application
    Filed: February 26, 2010
    Publication date: February 9, 2012
    Applicant: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventors: Rei Shibata, Toyoaki Murohama