Patents by Inventor Reid Kowallis

Reid Kowallis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20070134710
    Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. The device includes a substrate which defines a sample-distribution network having (i) a sample inlet, (ii) one or more detection chambers, and (iii) channel means providing a dead-end fluid connection between each of the chambers and the inlet Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
    Type: Application
    Filed: January 9, 2007
    Publication date: June 14, 2007
    Applicant: Applera Corporation
    Inventors: Timothy Woudenberg, Michael Albin, Reid Kowallis, Yefim Raysberg, Robert Ragusa, Emily Winn-Deen
  • Publication number: 20070128652
    Abstract: The present invention provides, in one aspect, an apparatus that comprises a disc-shaped substrate defining (1) a central reservoir region, (2) a plurality of channels in fluid communication with, and emanating substantially radially from, the central reservoir region, the channels being coplanar with each other, and each channel having (i) a proximal end which is linked to the reservoir region, and (ii) a distal end, and preferably (3) for each channel, at least one chamber, and preferably three chambers, linked by a passageway in fluid communication with the distal end of that channel.
    Type: Application
    Filed: December 29, 2006
    Publication date: June 7, 2007
    Applicant: Applera Corporation
    Inventors: Timothy Woudenberg, Reid Kowallis
  • Publication number: 20070111300
    Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. The device includes a substrate which defines a sample-distribution network having (i) a sample inlet, (ii) one or more detection chambers, and (iii) channel means providing a dead-end fluid connection between each of the chambers and the inlet. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
    Type: Application
    Filed: January 9, 2007
    Publication date: May 17, 2007
    Applicant: Applera Corporation
    Inventors: Timothy Woudenberg, Michael Albin, Reid Kowallis, Yefim Raysberg, Robert Ragusa, Emily Winn-Deen
  • Publication number: 20070111299
    Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. The device includes a substrate which defines a sample-distribution network having (i) a sample inlet, (ii) one or more detection chambers, and (iii) channel means providing a dead-end fluid connection between each of the chambers and the inlet. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
    Type: Application
    Filed: January 9, 2007
    Publication date: May 17, 2007
    Applicant: Applera Corporation
    Inventors: Timothy Woudenberg, Michael Albin, Reid Kowallis, Yefim Raysberg, Robert Ragusa, Emily Winn-Deen
  • Publication number: 20060210439
    Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. The device can comprise wells and each well can comprise an analyte-specific reagent effective to react with a selected analyte that may be present in the sample. Also disclosed are methods utilizing the device.
    Type: Application
    Filed: May 16, 2006
    Publication date: September 21, 2006
    Applicant: Applera Corporation
    Inventors: Timothy Woudenberg, Michael Albin, Reid Kowallis, Yefim Raysberg, Robert Ragusa, Emily Winn-Deen
  • Patent number: 7108775
    Abstract: The present teachings provide a microfluidic apparatus comprising a body defining at least one channel that extends through said body, the channel including an inlet and an outlet; and an electrode positioned in proximity to the body and configured to provide an electrical field near the outlet of the channel to at least partially confine an eluted sample component passing from the channel. The present teachings also provide an electrophoresis system, comprising a microfluidic chip defining a plurality of channels passing therethrough, each of the channels having an inlet and an outlet; a first electrode in electrical communication with the inlet of each of the channels; a second electrode in electrical communication with the outlet of each of the channels; and a third electrode in electrical communication with the outlet of each of the channels, wherein the third electrode is positioned to provide an electrical field to at least partially confine an eluted sample component passing from any of the channels.
    Type: Grant
    Filed: November 8, 2002
    Date of Patent: September 19, 2006
    Assignee: Applera Corporation
    Inventors: Dar Bahatt, Reid Kowallis
  • Publication number: 20060204401
    Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
    Type: Application
    Filed: May 10, 2006
    Publication date: September 14, 2006
    Applicant: Applera Corporation
    Inventors: Timothy Woudenberg, Michael Albin, Reid Kowallis, Yefim Raysberg, Robert Ragusa, Emily Winn-Deen
  • Publication number: 20060188917
    Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
    Type: Application
    Filed: April 7, 2006
    Publication date: August 24, 2006
    Applicant: Applera Corporation
    Inventors: Timothy Woudenberg, Michael Albin, Reid Kowallis, Yefim Raysberg, Robert Ragusa, Emily Winn-Deen
  • Publication number: 20060183151
    Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
    Type: Application
    Filed: April 7, 2006
    Publication date: August 17, 2006
    Applicant: Applera Corporation
    Inventors: Timothy Woudenberg, Michael Albin, Reid Kowallis, Yefim Raysberg, Robert Ragusa, Emily Winn-Deen
  • Publication number: 20060166352
    Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
    Type: Application
    Filed: February 24, 2006
    Publication date: July 27, 2006
    Applicant: Applera Corporation
    Inventors: Timothy Woudenberg, Michael Albin, Reid Kowallis, Yefim Raysberg, Robert Ragusa, Emily Winn-Deen
  • Publication number: 20060127939
    Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
    Type: Application
    Filed: January 27, 2006
    Publication date: June 15, 2006
    Applicant: Applera Corporation
    Inventors: Timothy Woudenberg, Michael Albin, Reid Kowallis, Yefim Raysberg, Robert Raqusa, Emily Winn-Deen
  • Publication number: 20060128007
    Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
    Type: Application
    Filed: February 8, 2006
    Publication date: June 15, 2006
    Applicant: Applera Corporation
    Inventors: Timothy Woudenberg, Michael Albin, Reid Kowallis, Yefim Raysberg, Robert Ragusa, Emily Winn-Deen
  • Publication number: 20050186684
    Abstract: A method for making a test device is provided. The method can comprise providing (a) a substrate comprising a plurality of wells, wherein each well comprises at least one dimension no greater than 1 mm; (ii) a robotic dispensing system comprising at least one piezoelectric dispenser; and (iii) a liquid solution comprising at least one analyte-specific reagent. The method further comprises delivering a volume of the liquid solution into at least some of the wells using the at least one piezoelectric dispenser. The volume can be no greater than about 1 microliter. The method can further comprise placing a cover over the wells.
    Type: Application
    Filed: April 12, 2005
    Publication date: August 25, 2005
    Applicant: Applera Corporation
    Inventors: Timothy Woudenberg, Michael Albin, Reid Kowallis, Yefim Raysberg, Robert Ragusa, Emily Winn-Deen
  • Publication number: 20050158781
    Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
    Type: Application
    Filed: January 5, 2005
    Publication date: July 21, 2005
    Applicant: Applera Corporation
    Inventors: Timothy Woudenberg, Michael Albin, Reid Kowallis, Yefim Raysberg, Robert Raqusa, Emily Winn-Deen
  • Publication number: 20050152810
    Abstract: Generally, the present invention provides a device and method for accurately locating a multi-well plate at a plate-support location, e.g., a work surface, of an automated laboratory machine, such that one or more acting members of the machine, such as an array of pipette tips, optical sensors, or the like, can accurately address and operate on the individual wells. Interior and/or exterior surface regions of one or more wells of a multi-well plate are used as the primary plate features engaged by locating structure of the machine. In one particular embodiment one or more upwardly tapered projections extend from a plate-support surface of a plate-handling machine for mating engagement with the exterior surface regions of one or more wells. In another embodiment, the exterior surface regions along one or more well bottoms are engagingly received within bores, or other receiving structure, formed on the plate-support surface of a machine.
    Type: Application
    Filed: February 28, 2005
    Publication date: July 14, 2005
    Applicant: Applera Corporation
    Inventors: Reid Kowallis, David Cox
  • Publication number: 20050061669
    Abstract: Bubble-free electrodes, electrochemical cells including bubble-free electrodes, analytical devices, and methods for preparing and using them are provided. The analytical devices each include at least one bubble-free electrode. Analytical devices that include an electrochemical cell and a sample containment device are also provided, wherein the electrochemical cell includes an anodic reservoir, a cathodic reservoir, an electrical connection between the anodic reservoir and the cathodic reservoir, and a first bubble-free electrode disposed within one of the anodic reservoir and the cathodic reservoir. A second electrode is disposed within the other reservoir and a power source is provided having a positive terminal that is normally in electrical contact with the first electrode, and a negative terminal that is normally in electrical contact with the second electrode.
    Type: Application
    Filed: November 9, 2004
    Publication date: March 24, 2005
    Applicant: Applera Corporation
    Inventors: Timothy Woudenberg, Zbigniew Bryning, Reid Kowallis
  • Publication number: 20040089546
    Abstract: The present teachings provide a microfluidic apparatus comprising a body defining at least one channel that extends through said body, the channel including an inlet and an outlet; and an electrode positioned in proximity to the body and configured to provide an electrical field near the outlet of the channel to at least partially confine an eluted sample component passing from the channel. The present teachings also provide an electrophoresis system, comprising a microfluidic chip defining a plurality of channels passing therethrough, each of the channels having an inlet and an outlet; a first electrode in electrical communication with the inlet of each of the channels; a second electrode in electrical communication with the outlet of each of the channels; and a third electrode in electrical communication with the outlet of each of the channels, wherein the third electrode is positioned to provide an electrical field to at least partially confine an eluted sample component passing from any of the channels.
    Type: Application
    Filed: November 8, 2002
    Publication date: May 13, 2004
    Inventors: Dar Bahatt, Reid Kowallis