Patents by Inventor Reidar Wallin

Reidar Wallin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHOD FOR INCREASING PRODUCTION OF RECOMBINANT GAMMA-CARBOXYLATED PROTEINS
    Publication number: 20140227248
    Abstract: Methods and cell lines for overexpressing functional gamma-carboxylated proteins are disclosed.
    Type: Application
    Filed: February 6, 2014
    Publication date: August 14, 2014
    Inventor: Reidar Wallin
  • Compositions and methods for increasing production of recombinant gamma-carboxylated proteins
    Patent number: 8647868
    Abstract: Methods and cell lines for overexpressing functional gamma-carboxylated proteins are disclosed by way of genetically engineered cell lines which over-express VKORC1. Also disclosed is the antisense inhibition of expression of calumenin in conjunction with overexpression of VKORC1 which also increases expression of functional gamma-carboxylated proteins. Gamma-carboxylated proteins of interest may include blood coagulation factors such as human clotting factors IX and VII.
    Type: Grant
    Filed: December 4, 2006
    Date of Patent: February 11, 2014
    Assignee: Wake Forest University Health Sciences
    Inventor: Reidar Wallin
  • Compositions and Methods for Increasing Production of Recombinant Gamma-Carboxylated Proteins
    Publication number: 20100331255
    Abstract: Methods and cell lines for overexpressing functional gamma-carboxylated proteins are disclosed by way of genetically engineered cell lines which over-express VKORC1. Also disclosed is the antisense inhibition of expression of calumenin in conjunction with overexpression of VKORC1 which also increases expression of functional gamma-carboxylated proteins. Gamma-carboxylated proteins of interest may include blood coagulation factors such as human clotting factors IX and VII.
    Type: Application
    Filed: December 4, 2006
    Publication date: December 30, 2010
    Inventor: Reidar Wallin