Patents by Inventor Reiji TANAKA

Reiji TANAKA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF TREATMENT USING 4-DEOXY-L-ERYTHRO-5-HEXOSEUROSE URONIC ACID
    Publication number: 20230404938
    Abstract: A method of treating a patient in need thereof includes administering a therapeutically effective amount of 4-deoxy-L-erythro-5-hexoseulose uronic acid (DEH) to serve or function as a nerve growth factor (NGF) activity promoter, preferably to treat and/or prevent a neurodegenerative disease, such as PolyQ disease, Parkinson's disease, Parkinson's syndrome, spinocerebellar degeneration, spastic paraplegia, amyotrophic lateral sclerosis, Alzheimer's disease, dementia with Lewy bodies or corticobasal degeneration.
    Type: Application
    Filed: March 16, 2023
    Publication date: December 21, 2023
    Applicant: MIE UNIVERSITY
    Inventors: Toshiyuki SHIBATA, Hideo MIYAKE, Reiji TANAKA, Fumino OKUDA, Mano HASEGAWA
  • DNA sequence and expression vector for alginate lyase
    Patent number: 10927363
    Abstract: Alginate lyase activity is exhibited by the amino acid sequences (polypeptides) shown in SEQ ID No:1 and SEQ ID No:2. These polypeptides and their homology equivalents are used to produce 4-deoxy-L-erythro-5-hexoseulose uronic acid (DEH) by contacting the polypeptide(s) with an alginate containing a uronic acid moiety and holding the mixture of the alginate and the polypeptide(s) at a temperature at which alginate lyase activity is exhibited.
    Type: Grant
    Filed: April 3, 2017
    Date of Patent: February 23, 2021
    Assignee: MIE UNIVERSITY
    Inventors: Toshiyuki Shibata, Hideo Miyake, Yoshihiro Murase, Reiji Tanaka, Tetsushi Mori, Haruko Takeyama, Mami Takahashi
  • ALGINATE LYASES AND A METHOD FOR PRODUCING UNSATURATED URONIC ACID MONOSACCHARIDE USING THE ENZYMES
    Publication number: 20190127722
    Abstract: Alginate lyase activity is exhibited by the amino acid sequences (polypeptides) shown in SEQ ID No:1 and SEQ ID No:2. These polypeptides and their homology equivalents are used to produce 4-deoxy-L-erythro-5-hexoseulose uronic acid (DEH) by contacting the polypeptide(s) with an alginate containing a uronic acid moiety and holding the mixture of the alginate and the polypeptide(s) at a temperature at which alginate lyase activity is exhibited.
    Type: Application
    Filed: April 3, 2017
    Publication date: May 2, 2019
    Inventors: Toshiyuki SHIBATA, Hideo MIYAKE, Yoshihiro MURASE, Reiji TANAKA, Tetsushi MORI, Haruko TAKEYAMA, Mami TAKAHASHI