Patents by Inventor Reinhard Brossmer

Reinhard Brossmer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sialic acid derivatives
    Patent number: 10472381
    Abstract: Sialic acid derivatives of the formula (I)
    Type: Grant
    Filed: February 25, 2015
    Date of Patent: November 12, 2019
    Assignees: Reinhard Brossmer, Horst Prescher
    Inventors: Reinhard Brossmer, Horst Prescher
  • Sialic acid derivatives
    Patent number: 9539336
    Abstract: A sialic acid derivative of the formula (I), where the symbols are as defined in the description, is suitable for linking with a cargo for regulating metabolic processes, immune reactions, immunizations or desensitizations of the target organism.
    Type: Grant
    Filed: June 21, 2013
    Date of Patent: January 10, 2017
    Inventors: Reinhard Brossmer, Horst Prescher
  • SIALIC ACID DERIVATIVES
    Publication number: 20160362436
    Abstract: Sialic acid derivatives of the formula (I)
    Type: Application
    Filed: February 25, 2015
    Publication date: December 15, 2016
    Inventors: Reinhard BROSSMER, Horst PRESCHER
  • Sialic acid dimers
    Patent number: 9260467
    Abstract: Sialic acid derivatives of the formula (I) in which the symbols have the definitions stated in the description are suitable as medicaments, more particularly for diseases whose course is influenced by Siglec ligands.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: February 16, 2016
    Inventors: Reinhard Brossmer, Horst Prescher
  • Sialic Acid Derivatives
    Publication number: 20150174262
    Abstract: A sialic acid derivative of the formula (I), where the symbols are as defined in the description, is suitable for linking with a cargo for regulating metabolic processes, immune reactions, immunizations or desensitizations of the target organism.
    Type: Application
    Filed: June 21, 2013
    Publication date: June 25, 2015
    Inventors: Reinhard Brossmer, Horst Prescher
  • Sialic Acid Dimers
    Publication number: 20150005245
    Abstract: Sialic acid derivatives of the formula (I) in which the symbols have the definitions stated in the description are suitable as medicaments, more particularly for diseases whose course is influenced by Siglec ligands.
    Type: Application
    Filed: December 21, 2012
    Publication date: January 1, 2015
    Inventors: Reinhard Brossmer, Horst Prescher
  • Siglec inhibitors
    Patent number: 7820714
    Abstract: The invention relates to Siglec inhibitors that have an increased affinity for the receptor molecule. The Siglec inhibitors provided by the invention are preferably selective of a given Siglec molecule. The invention further relates to a method for producing Siglec inhibitors and to a method for increasing the binding selectivity for a given Siglec molecule. The invention also relates to pharmaceutical compositions that contain the Siglec inhibitors and to medical indications for the Siglec inhibitors.
    Type: Grant
    Filed: June 7, 2002
    Date of Patent: October 26, 2010
    Inventors: Sorge Kelm, Reinhard Brossmer
  • Glycoconjugates of sialic acid derivates, methods for their production and use thereof
    Publication number: 20050042714
    Abstract: The present invention relates to glycoconjugates containing a sialic acid derivate of general formula (I) and wherein the sialic acid derivate of general formula (I) is conjugated to a mono-, di- or oligosaccharide with up to 40 glycosidically linked, optionally branched sugar residues representing furanose and/or pyranose rings, which are linked N- or O-glycosidically to the polypeptide. The sialic derivatives of general formula (I) are useful for producing pharmaceutical compositions for immunosuppression, cell protection, stimulation of hematopoesis regulation of hormonal secretion and hormonal activation.
    Type: Application
    Filed: August 17, 2002
    Publication date: February 24, 2005
    Inventors: Michael Pawlita, Cornelia Oetke, Oliver Keppler, Reinhard Brossmer, Stephan Hinderlich, Werner Reutter
  • Siglec inhibitors
    Publication number: 20040176309
    Abstract: The invention relates to Siglec inhibitors that have an increased affinity for the receptor molecule. The Siglec inhibitors provided by the invention are preferably selective of a given Siglec molecule. The invention further relates to a method for producing Siglec inhibitors and to a method for increasing the binding selectivity for a given Siglec molecule. The invention also relates to pharmaceutical compositions that contain the Siglec inhibitors and to medical indications for the Siglec inhibitors.
    Type: Application
    Filed: February 13, 2004
    Publication date: September 9, 2004
    Inventors: Sorge Kelm, Reinhard Brossmer
  • CMP-activated, fluorescing sialic acids, as well as processes for their preparation
    Patent number: 5405753
    Abstract: A process for preparing CMP-activated fluorescence indicator-labelled sialic acids is disclosed. According to the process, a 5-acylamido-9-amino-3,5,9-tridesoxy-.beta.-D-glycero-D-galactonoulosonic acid or 5-aminoacylamido-3,5-didesoxy-.beta.-D-glycero-D-galactonoulosonic acid is reacted with cytidine phosphate in the presence of a CMP-sialic acid synthase which is then reacted with a fluorescing compound to give a CMP-activated fluorescing sialic acid. Also disclosed are novel CMP-activated fluorescing sialic acids.
    Type: Grant
    Filed: September 28, 1992
    Date of Patent: April 11, 1995
    Inventors: Reinhard Brossmer, Hans J. Gross