Patents by Inventor Reinhard Krämer

Reinhard Krämer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160244490
    Abstract: The invention relates to a microorganism which produces and/or secretes an organic-chemical compound, wherein the microorganism has increased expression, compared to the particular starting strain, of one or more protein subunits of the ABC transporter having the activity of a trehalose importer, said microorganism being capable of taking up trehalose from the medium; and to a method for the production of an organic-chemical compound, using the microorganism according to the invention, wherein accumulation of trehalose in the fermentation broth is reduced or avoided.
    Type: Application
    Filed: May 5, 2016
    Publication date: August 25, 2016
    Applicant: Evonik Degussa GmbH
    Inventors: Stephan Hans, Brigitte Bathe, Alexander Reth, Wilfried Claes, Reinhard Krämer, Gerd Seibold, Alexander Henrich
  • Patent number: 9359413
    Abstract: The invention relates to a microorganism which produces and/or secretes an organic-chemical compound, wherein the microorganism has increased expression, compared to the particular starting strain, of one or more protein subunits of the ABC transporter having the activity of a trehalose importer, said microorganism being capable of taking up trehalose from the medium; and to a method for the production of an organic-chemical compound, using the microorganism according to the invention, wherein accumulation of trehalose in the fermentation broth is reduced or avoided.
    Type: Grant
    Filed: April 3, 2012
    Date of Patent: June 7, 2016
    Assignee: Evonik Degussa GmbH
    Inventors: Stephan Hans, Brigitte Bathe, Alexander Reth, Wilfried Claes, Reinhard Krämer, Gerd Seibold, Alexander Henrich
  • Publication number: 20120252075
    Abstract: The invention relates to a microorganism which produces and/or secretes an organic-chemical compound, wherein the microorganism has increased expression, compared to the particular starting strain, of one or more protein subunits of the ABC transporter having the activity of a trehalose importer, said microorganism being capable of taking up trehalose from the medium; and to a method for the production of an organic-chemical compound, using the microorganism according to the invention, wherein accumulation of trehalose in the fermentation broth is reduced or avoided.
    Type: Application
    Filed: April 3, 2012
    Publication date: October 4, 2012
    Applicant: Evonik Degussa GmbH
    Inventors: Stephan Hans, Brigitte Bathe, Alexander Reth, Wilfried Claes, Reinhard Krämer, Gerd Seibold, Alexander Henrich
  • Publication number: 20050266536
    Abstract: A process for the preparation of L-amino acids, in which the following steps are carried out: (a) fermentation of the coryneform bacteria which produce the desired L-amino acid and in which at least the gene which codes for trehalose phosphatase and/or the gene which codes for maltooligosyl-trehalose synthase and/or the gene which codes for maltooligosyl-trehalose trehalohydrolase is or are attenuated, (b) concentration of the desired L-amino acid in the medium or in the cells of the bacteria, and (c) isolation of the L-amino acid, and optionally bacteria in which further genes of the biosynthesis pathway of the desired L-amino acid are addtionally enhanced are employed, or bacteria in which the metabolic pathways which reduce the formation of the desired L-amino acid are at least partly eliminated are employed.
    Type: Application
    Filed: May 9, 2005
    Publication date: December 1, 2005
    Applicant: Degussa AG
    Inventors: Andreas Wolf, Natalie Schischka, Thomas Hermann, Susanne Morbach, Reinhard Kraemer
  • Publication number: 20040229255
    Abstract: The present invention provides nucleotide sequences from Coryneform bacteria which code for the OtsA protein and processes for the fermentative preparation of amino acids using bacteria in which the otrA gene is attenuated.
    Type: Application
    Filed: March 17, 2004
    Publication date: November 18, 2004
    Applicant: DEGUSSA AG
    Inventors: Thomas Hermann, Andreas Wolf, Susanne Morbach, Reinhard Kraemer
  • Publication number: 20030092139
    Abstract: A process for the preparation of L-amino acids, in which the following steps are carried out:
    Type: Application
    Filed: August 6, 2002
    Publication date: May 15, 2003
    Applicant: Degussa AG
    Inventors: Andreas Wolf, Natalie Schischka, Thomas Hermann, Susanne Morbach, Reinhard Kraemer
  • Publication number: 20020192674
    Abstract: The present invention provides nucleotide sequences from Coryneform bacteria which code for the OtsA protein and processes for the fermentative preparation of amino acids using bacteria in which the otrA gene is attenuated.
    Type: Application
    Filed: January 30, 2002
    Publication date: December 19, 2002
    Applicant: Degussa AG
    Inventors: Thomas Hermann, Andreas Wolf, Susanne Morbach, Reinhard Kraemer