Abstract: The use of .alpha.,.alpha.-diphenylacetic acid-4-(N-methyl-piperidyl) ester for the treatment of painful muscular cramp conditions in the region of the abdominal cavity or for the production of drugs for the treatment of painful muscular cramp conditions in the region of the abdominal cavity.

Abstract: 4-(Hydroxydiphenylmethyl)-1-piperidylphenylalkane derivatives as antihistamines of the formula ##STR1## and pharmaceutically acceptable salts of such derivatives are disclosed in whichn is an integer between 0 and 2,R.sup.1 -R.sup.5 represent, independently of one another, hydrogen and at least one of them represents a linear or branched alkyl radical with 1-4 carbon atoms, a C.sub.1 -C.sub.3 -alkoxy radical or a hydroxyl radical. A method of treatment of allergic response in mammals is also disclosed.

Abstract: Certain acylated benzilic acid derivatives are useful for influencing therapeutically the tone of the urinary bladder in humans and animals. These derivatives are N-alkyl-4-piperidyl .alpha.,.alpha.-diphenyl-.alpha.-acyloxyacetates having the formula ##STR1## wherein R is H, CH.sub.3, C.sub.2 H.sub.5 or C.sub.3 H.sub.7 ; R' is H, NH.sub.2, phenyl, carboxyphenyl, (C.sub.1 -C.sub.6)alkyl, hydroxy(C.sub.1 -C.sub.6)alkyl, methoxy, ethoxy, methoxymethyl, ethoxymethyl, amino(C.sub.1 -C.sub.6)alkyl which can be substituted in the alkyl radical by one or more of a --NH.sub.2, --COOH or --SCH.sub.3 group, N-acetylamino(C.sub.1 -C.sub.6)alkyl, or a group having the formula--CH.dbd.CH--COOR"or--(CH.sub.2).sub.n --COOR"where n is an integer from 0 to 8, and R" is H, CH.sub.3, C.sub.2 H.sub.5, C.sub.3 H.sub.7, or a pharmacologically acceptable cation; or a salt thereof with a pharmaceutically acceptable acid.

Abstract: Certain acylated benzilic acid derivatives are useful for influencing therapeutically the tone of the urinary bladder in humans and animals. These derivatives are N-alkyl-4-piperidyl .alpha.,.alpha.-diphenyl-.alpha.-acyloxyacetates having the formula ##STR1## wherein R is H, CH.sub.3, C.sub.2 H.sub.5 or C.sub.3 H.sub.7 ; R' is H, NH.sub.2, phenyl, carboxyphenyl, (C.sub.1 -C.sub.6)alkyl, hydroxy(C.sub.1 -C.sub.6)alkyl, methoxy, ethoxy, methoxymethyl, ethoxymethyl, amino (C.sub.1 -C.sub.6)alkyl which can be substituted in the alkyl radical by one or more of a --NH.sub.2, --COOH or --SCH.sub.3 group, N-acetylamino (C.sub.1 -C.sub.6)alkyl, or a group having the formula--CH.dbd.CH--COOR" or --(CH.sub.2).sub.n --COOR"where n is an integer from 0 to 8, and R" is H, CH.sub.3, C.sub.2 H.sub.5, C.sub.3 H.sub.7, or a pharmacologically acceptable cation; or a salt thereof with a pharmaceutically acceptable acid.