Patents by Inventor Reinhard Luehrmann

Reinhard Luehrmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RNA-interference by single-stranded RNA molecules
    Patent number: 10023865
    Abstract: The present invention relates to sequence and structural features of single-stranded (ss)RNA molecules required to mediate target-specific nucleic acid modifications by RNA-interference (RNAi), such as target mRNA degradation and/or DNA methylation.
    Type: Grant
    Filed: September 7, 2016
    Date of Patent: July 17, 2018
    Assignee: Max-Planck-Gesellschaft zur Förderung de Wissenschaften e.V.
    Inventors: Thomas Tuschl, Javier Martinez, Agnieszka Patkaniowska, Henning Urlaub, Reinhard Luehrmann
  • RNA-INTERFERENCE BY SINGLE-STRANDED RNA MOLECULES
    Publication number: 20170067050
    Abstract: The present invention relates to sequence and structural features of single-stranded (ss)RNA molecules required to mediate target-specific nucleic acid modifications by RNA-interference (RNAi), such as target mRNA degradation and/or DNA methylation.
    Type: Application
    Filed: September 7, 2016
    Publication date: March 9, 2017
    Applicant: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Thomas TUSCHL, Javier MARTINEZ, Agnieszka PATKANIOWSKA, Henning URLAUB, Reinhard LUEHRMANN
  • RNA-interference by single-stranded RNA molecules
    Patent number: 9476044
    Abstract: The present invention relates to sequence and structural features of single-stranded (ss)RNA molecules required to mediate target-specific nucleic acid modifications by RNA-interference (RNAi), such as target mRNA degradation and/or DNA methylation.
    Type: Grant
    Filed: July 22, 2014
    Date of Patent: October 25, 2016
    Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Thomas Tuschl, Javier Martinez, Agnieszka Patkaniowska, Henning Urlaub, Reinhard Luehrmann
  • RNA-INTERFERENCE BY SINGLE-STRANDED RNA MOLECULES
    Publication number: 20150096064
    Abstract: The present invention relates to sequence and structural features of single-stranded (ss)RNA molecules required to mediate target-specific nucleic acid modifications by RNA-interference (RNAi), such as target mRNA degradation and/or DNA methylation.
    Type: Application
    Filed: July 22, 2014
    Publication date: April 2, 2015
    Applicant: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Thomas TUSCHL, Javier MARTINEZ, Agnieszka PATKANIOWSKA, Henning URLAUB, Reinhard LUEHRMANN
  • Inducible small RNA expression constructs for targeted gene silencing
    Patent number: 8470797
    Abstract: The invention relates to vectors for the inducible expression of RNA molecules in eukaryotic, particularly mammalian cells and transgenic animals.
    Type: Grant
    Filed: April 3, 2012
    Date of Patent: June 25, 2013
    Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Thomas Tuschl, Tilmann Achsel, Reinhard Luehrmann, Jutta Myer
  • INDUCIBLE SMALL RNA EXPRESSION CONSTRUCTS FOR TARGETED GENE SILENCING
    Publication number: 20120255045
    Abstract: The invention relates to vectors for the inducible expression of RNA molecules in eukaryotic, particularly mam
    Type: Application
    Filed: April 3, 2012
    Publication date: October 4, 2012
    Applicant: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Thomas Tuschl, Tilmann Achsel, Reinhard Lührmann, Jutta Meyer
  • RNA-INTERFERENCE BY SINGLE-STRANDED RNA MOLECULES
    Publication number: 20120246747
    Abstract: The present invention relates to sequence and structural features of single-stranded (ss)RNA molecules required to mediate target-specific nucleic acid modifications by RNA-interference (RNAi), such as target mRNA degradation and/or DNA methylation.
    Type: Application
    Filed: December 19, 2011
    Publication date: September 27, 2012
    Applicant: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Thomas TUSCHL, Javier Martinez, Agnieszka Patkaniowska, Henning Urlaub, Reinhard Lührmann
  • Inducible small RNA expression constructs for targeted gene silencing
    Patent number: 8198077
    Abstract: The invention relates to vectors for the inducible expression of RNA molecules in eukaryotic, particularly mammalian cells and transgenic animals.
    Type: Grant
    Filed: January 15, 2004
    Date of Patent: June 12, 2012
    Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Thomas Tuschl, Tilmann Achsel, Reinhard Lührmann, Jutta Meyer
  • RNA-interference by single-stranded RNA molecules
    Patent number: 8101348
    Abstract: The present invention relates to sequence and structural features of single-stranded (ss) RNA molecules required to mediate target-specific nucleic acid modifications by RNA-interference (RNAi), such as target mRNA degradation and/or DNA methylation.
    Type: Grant
    Filed: July 10, 2003
    Date of Patent: January 24, 2012
    Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Thomas Tuschl, Javier Martinez, Agnieszka Patkaniowska, Henning Urlaub, Reinhard Luehrmann
  • Test system for detecting a splicing reaction and use thereof
    Patent number: 6579681
    Abstract: The present invention relates to a test system comprising (a) one or more identical or different immobilized nucleic acid(s) having at least one spliceable nucleic acid, (b) at least one gel-free detection system for detecting a splicing reaction, where appropriate (c) at least one composition comprising splicing components, and preferably (d) suitable detection probes, and, where appropriate, (e) further aids.
    Type: Grant
    Filed: November 27, 2001
    Date of Patent: June 17, 2003
    Assignee: Aventis Research and Technologies GmbH & Co. KG
    Inventors: Christoph Hüls, Bettina Bauer, Claus Simandi, Reinhard Lührmann, Tilmann Achsel, Hans-Peter Vornlocher
  • Nucleic acid constructs containing genes encoding transport signals
    Patent number: 6235526
    Abstract: Nucleic acid constructs are disclosed which possess a nuclear retention signal which is linked, downstream in the reading direction, to a transgene. The nuclear retention signal can regulate the presence of the transcription product in the cell nucleus or else the intracellular transport of the transcription product.
    Type: Grant
    Filed: May 2, 1997
    Date of Patent: May 22, 2001
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Hans-Harald Sedlacek, Rolf Mueller, Reinhard Luehrmann