Abstract: Pharmaceutical formulation in the form of a solid dispersion, wherein the solid dispersion comprises in admixture a cannabinoid, an amphiphilic block copolymer as a solubilizer and a water-soluble film former. A method for preparing a formulation as defined, wherein the method comprises the following steps: (i) preparing a liquid composition comprising the cannabinoid, the amphiphilic block copolymer and a solvent capable of at least partially dissolving the cannabinoid and the amphiphilic block copolymer; (ii) introducing the liquid composition into a fluid bed granulator; (iii) removing solvent to obtain a solid dispersion in particulate form; and (iv) recovering the solid dispersion in particulate form from the fluid bed granulator.

Abstract: A method, a repair device and a repair system for repairing a corrosion damage of a surface of an object exposed to weather. The method includes laserless pre-cleaning of the surface with the corrosion damage, laser cleaning of the surface with the corrosion damage and coating of the surface treated by laser cleaning with a protective layer.

Abstract: A method for monitoring a nozzle mouthpiece for placing on a nozzle for spraying materials, in particular dispersions, emulsions or suspensions.

Abstract: Compositions for the immediate release of one or more cannabinoids, in which the compositions comprise a population of particles. Each particle may comprise the one or more cannabinoids and one or more intra-granule excipients. Alternatively, each particle may comprise the one or more cannabinoids and a porous bead core. The composition may be prepared by a method that involves combining the one or more cannabinoids with the one or more intra-granule excipients, and then granulating the combination, such as through fluid bed granulation, shear-induced wet granulation, or spray granulation. The composition may also be prepared by a method that involves mixing the one or more cannabinoids with a population of porous bead cores.

Abstract: A filling unit for filling cavities in a tablet press with a feedstock to be pressed, particularly a powder, having a filling assembly including a fill chamber. The fill chamber is arranged in the installed condition between a die table containing the cavities and a punch support including at least one punch. The fill chamber has at least one inlet opening for filling the fill chamber with raw material and at least one outlet opening for filling the cavities of the tablet press with feedstock to be pressed. The filling chamber has at least one mixer for mixing the raw materials of the feedstock to be pressed arranged at least partially in the fill chamber and at least one delivery unit for filling the cavities of the tablet press with feedstock to be pressed.

Abstract: Described is a nozzle for spraying substances, in particular dispersions, emulsions or suspensions.

Abstract: A nozzle for spraying substances, more particularly dispersions, emulsions or suspensions, and to a method for the open-loop or closed-loop control of the volumetric flow rate of a substance to be sprayed and/or of a gas of a nozzle suitable for spraying substances, more particularly dispersions, emulsions or suspensions. The nozzle includes an inner tube discharge opening and a constriction in an inner tube channel carrying the substance to be sprayed at a distance from the inner tube discharge opening.

Abstract: Uses and formulations of cannabinoids, in particular of cannabidiol, are provided. The cannabinoids, in particular cannabidiol, are used for the treatment of patients suffering from inflammatory conditions associated with autoimmune diseases, chronic inflammatory diseases and inflammatory conditions in connection with infections, including cytokine release syndrome (CRS). Formulations are especially for oral administration of cannabinoids, in particular of cannabidiol. These formulations are useful for treating patients suffering from conditions as referred to above.

Abstract: Uses and formulations of cannabinoids, in particular of cannabidiol, are provided. The cannabinoids, in particular cannabidiol, are used for the treatment of patients suffering from COVID-19, a disease caused by the coronavirus SARS-Cov-2. Formulations are especially for oral administration of cannabinoids, in particular of cannabidiol. These formulations are useful for treating patients suffering from COVID-19.

Abstract: Uses and formulations of cannabinoids, in particular of cannabidiol, are provided. The cannabinoids, in particular cannabidiol, are used for the treatment of patients suffering from COVID-19, a disease caused by the coronavirus SARS-Cov-2. Formulations are especially for oral administration of cannabinoids, in particular of cannabidiol. These formulations are useful for treating patients suffering from COVID-19.

Abstract: Uses and formulations of cannabinoids, in particular of cannabidiol, are provided. The cannabinoids, in particular cannabidiol, are used for the treatment of patients suffering from inflammatory conditions associated with autoimmune diseases, chronic inflammatory diseases and inflammatory conditions in connection with infections, including cytokine release syndrome (CRS). Formulations are especially for oral administration of cannabinoids, in particular of cannabidiol. These formulations are useful for treating patients suffering from conditions as referred to above.

Abstract: A sealing device for sealing a pipeline arrangement, a method for the production of a sealing device, and a pipeline system including a sealing device and a pipeline arrangement. The sealing device includes a seal and data medium assigned to the seal with electronic data memory to which seal specific information can be or is written.

Abstract: Provided is a device for granulating, agglomerating, pelletising, drying and/or coating, the device including a swirl chamber, a distribution chamber, wherein the swirl chamber is separated from the distribution chamber by a base and wherein a powder to be granulated or a powder mixture to be granulated is presented in the swirl chamber, the device further including at least one agitator for thoroughly mixing the powder to be granulated or the powder mixture to be granulated and at least one addition device for a liquid, wherein the base is designed in several parts and at least one base part is horizontally and/or vertically displaceable, with the result that that the base becomes a distributor plate. Also provided is a method for granulating, agglomerating, pelletising, drying and/or coating using such a device and a base suitable for use as a distributor plate in a convective drying apparatus.

Abstract: Compositions for the immediate release of one or more cannabinoids, in which the compositions comprise a population of particles. Each particle may comprise the one or more cannabinoids and one or more intra-granule excipients. Alternatively, each particle may comprise the one or more cannabinoids and a porous bead core. The composition may be prepared by a method that involves combining the one or more cannabinoids with the one or more intra-granule excipients, and then granulating the combination, such as through fluid bed granulation, shear-induced wet granulation, or spray granulation. The composition may also be prepared by a method that involves mixing the one or more cannabinoids with a population of porous bead cores.

Abstract: A method for manufacturing a pipe conduit arrangement including sticking a pipe stub onto a pipe conduit at least up to the flush state of the of the flange section end-face and the nips conduit end-face, fixing the pipe conduit in the pipe stub in a press fit which is produced by the radial widening of the pipe conduit, and axially clamping the arisen pipe conduit units by way of clamping the flange sections of the pine stubs into the nine conduit arrangement. Also described is a pipe conduit arrangement.

Abstract: A process for the continuous production of an active ingredient granulate is provided, which comprises the following steps: (a) preparing a spray composition by dissolving or dispersing an active ingredient and optionally one or more excipients in a liquid; (b) providing solid particles in a process space; (c) introducing droplets of the spray composition into an injection zone of the process space in which the liquid evaporates; (d) repeated guiding of the solid particles past the sprayed droplets in the process space with the aid of a process gas jet, so that at least a portion of the droplets, which may have already lost part of the liquid contained, comes into contact with solid particles and larger solid particles are formed through agglomeration; (e) removing the active ingredient granulate from the process space in the form of solid particles, wherein the active ingredient comprises metformin or an acid addition salt of metformin, in particular metformin hydrochloride.

Abstract: Compositions for the immediate release of one or more cannabinoids, in which the compositions comprise a population of particles. Each particle may comprise the one or more cannabinoids and one or more intra-granule excipients. Alternatively, each particle may comprise the one or more cannabinoids and a porous bead core. The composition may be prepared by a method that involves combining the one or more cannabinoids with the one or more intra-granule excipients, and then granulating the combination, such as through fluid bed granulation, shear-induced wet granulation, or spray granulation. The composition may also be prepared by a method that involves mixing the one or more cannabinoids with a population of porous bead cores.

Abstract: A method for the continuous production of an active ingredient granulate is provided, which comprises the following steps: (a) preparing a spray composition by dissolving or dispersing an active ingredient and optionally one or more excipients in a liquid; (b) providing solid particles in a process space; (c) introducing droplets of the spray composition into an injection zone of the process space in which the liquid evaporates; (d) repeatedly guiding the solid particles back past the sprayed droplets in the process space with the aid of a process gas jet, so that at least a portion of the droplets, which may have already lost part of the liquid contained, comes into contact with solid particles and larger solid particles are formed through agglomeration; (e) removing the active ingredient granulate from the process space in the form of solid particles, wherein the active ingredient in the form used has a Hausner factor of 1.19 or greater.

Abstract: An archiving system for archiving electronic data in memory of the archiving system in an audit-proof manner and a related method for archiving electronic data on the archiving system.

Abstract: A method for monitoring a nozzle mouthpiece for placing on a nozzle for spraying materials, in particular dispersions, emulsions or suspensions.