Patents by Inventor Reinhard Wähler

Reinhard Wähler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DELIVERY SYSTEM AND CONJUGATES FOR COMPOUND DELIVERY VIA NATURALLY OCCURRING INTRACELLULAR TRANSPORT ROUTES
    Publication number: 20140065172
    Abstract: The present invention relates to a delivery system that comprises a conjugate that facilitates the delivery of a compound such as a biologically-active macromolecule, a nucleic acid or a peptide in particular, into a cell. The present invention also relates to said conjugate for delivery of a compound, such as a biologically-active macromolecule, a nucleic acid or a peptide, into a cell. The present invention further relates to a pharmaceutical composition comprising said conjugate and to its use. The present invention also relates to a method of delivering a compound to a cell or an organism, preferably a patient.
    Type: Application
    Filed: January 26, 2012
    Publication date: March 6, 2014
    Inventors: Christophe J. Echeverri, Birte Sönnichsen, Reinhard Wähler, Mike Werner Helms, Brian S. Sproat
  • Delivery System and Conjugates For Compound Delivery Via Naturally Occurring Intracellular Transport Routes
    Publication number: 20120258104
    Abstract: The present invention relates to a delivery system that comprises a conjugate that facilitates the delivery of a compound such as a biologically-active macromolecule, a nucleic acid or a peptide in particular, into a cell. The present invention also relates to said conjugate for delivery of a compound, such as a biologically-active macromolecule, a nucleic acid or a peptide, into a cell. The present invention further relates to a pharmaceutical composition comprising said conjugate and to its use. The present invention also relates to a method of delivering a compound to a cell or an organism, preferably a patient.
    Type: Application
    Filed: July 22, 2010
    Publication date: October 11, 2012
    Applicant: Cenix Bioscience GMBH
    Inventors: Christophe J. Echeverri, Birte Sonnichsen, Reinhard Wähler, Mike Werner Helms
  • Viral vectors and the use of the same for gene therapy
    Patent number: 8067227
    Abstract: The invention relates to viral vectors comprising nucleic acid sequences coding for single chain interleukin-12 (single chain IL-12 or scIL12) and a costimulator protein, and to the use of vectors for gene therapy, especially for the treatment of tumors. The invention further relates to adenoviral vectors containing nucleic acid sequences having a sequence homology of at least 90% in relation to the sequence displayed in FIGS. 19 and 20 (IL-12), in FIG. 21 (4-1BB ligand) and in FIG. 22 (IL-2) and optionally also one of the sequences displayed in FIG. 23A (B7-1) or 23B (B7-2).
    Type: Grant
    Filed: October 10, 2003
    Date of Patent: November 29, 2011
    Assignee: Universitätsklinikum Hamburg-Eppendorf
    Inventors: Reinhard Wähler, Frank Schnieders