Patents by Inventor Reinhold E. Gerber

Reinhold E. Gerber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of detecting sequence variations in macromolecules by thermal gradiant
    Patent number: 6486309
    Abstract: The present invention describes a method for separating macromolecules, particularly heteroduplex from homoduplex DNA molecules. The macromolecules undergo a temperature sensitive structural denaturation which, when it occurs, results in a difference in the mobilities of the denatured components on a solid support. A polar to non-polar solvent gradient or modified solid support particular to each sample is not required, since the difference in mobility is achieved on conventional solid supports using a single mobile phase composition.
    Type: Grant
    Filed: August 1, 2001
    Date of Patent: November 26, 2002
    Assignee: Varian, Inc.
    Inventors: Reinhold E. Gerber, Richard G. Hatch