Patents by Inventor Reinhold Rose
Reinhold Rose has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20140293734Abstract: The invention relates to a reactor driven in an oscillatory-rotary manner about its fixed, preferably vertical, axis, for preferably biotechnological and pharmaceutical applications. By means of its process-intensifying properties for mixing, suspension, gaseous material transport, heat transfer, irradiation and particle retention, the applicability on the industrial scale is ensured. The reactor which succeeds without a shaft seal permits particularly robust production with respect to sterile technique with avoidance of cleaning and cleaning validation required when the reactor is constructed as a single-use reactor.Type: ApplicationFiled: May 15, 2014Publication date: October 2, 2014Inventors: Jörg KAULING, Helmut BROD, Sebastian SCHMIDT, Martin POGGEL, Björn FRAHM, Reinhold ROSE
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Publication number: 20140080213Abstract: The invention relates to a reactor driven in an oscillatory-rotary manner about its fixed, preferably vertical, axis, for preferably biotechnological and pharmaceutical applications. By means of its process-intensifying properties for mixing, suspension, gaseous material transport, heat transfer, irradiation and particle retention, the applicability on the industrial scale is ensured. The reactor which succeeds without a shaft seal permits particularly robust production with respect to sterile technique with avoidance of cleaning and cleaning validation required when the reactor is constructed as a single-use reactor.Type: ApplicationFiled: October 7, 2013Publication date: March 20, 2014Inventors: Jörg KAULING, Helmut BROD, Sebastian SCHMIDT, Martin POGGEL, Björn FRAHM, Reinhold ROSE
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Patent number: 8602636Abstract: The invention relates to a reactor driven in an oscillatory-rotary manner about its fixed, preferably vertical, axis, for preferably biotechnological and pharmaceutical applications. By means of its process-intensifying properties for mixing, suspension, gaseous material transport, heat transfer, irradiation and particle retention, the applicability on the industrial scale is ensured. The reactor which succeeds without a shaft seal permits particularly robust production with respect to sterile technique with avoidance of cleaning and cleaning validation required when the reactor is constructed as a single-use reactor.Type: GrantFiled: April 23, 2007Date of Patent: December 10, 2013Assignee: Bayer Intellectual Property GmbHInventors: Jörg Kauling, Helmut Brod, Sebastian Schmidt, Martin Poggel, Björn Frahm, Reinhold Rose
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Patent number: 7871193Abstract: A mixer having improved axial and radial mixing which retains good mixing time even during large viscosity changes, comprising a housing with at least one helical or anchor agitator located centrally in the housing in combination with at least one eccentrically arranged screw or blade agitator, preferably in mutual engagement, the combination of a helical agitator and a screw agitator enabling a much shorter mixing time as compared to a mixer having only a helical agitator without a screw agitator.Type: GrantFiled: July 2, 2005Date of Patent: January 18, 2011Assignee: Bayer Technology Services GmbHInventors: Helmut Brod, Stefanie Köhler, Reinhold Rose
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Publication number: 20090272683Abstract: The invention relates to a device (1) for the treatment of substance mixtures conveyed under high pressure, with a casing (3) surrounding a high-pressure space (2), with at least one sealing means (12) in order to seal off the high-pressure space (2) with respect to the surroundings, and with an inlet (4) and an outlet (5) in order respectively to supply the substance mixture to be treated to the high-pressure space (2) and to discharge it from the high-pressure space (2). The high-pressure space (2) is closed, via at least one cover for mounting and demounting, by a processing module arranged in the high-pressure space (2), the cover having a central fastening means (6) which can be locked, oriented coaxially with respect to the casing (3).Type: ApplicationFiled: February 12, 2007Publication date: November 5, 2009Applicant: BAYER TECHNOLOGY SERVICES GMBHInventors: Reinhold Rose, Olaf Behrend, Martin Poggel, Lars Obendorf
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Publication number: 20090180933Abstract: The invention relates to a reactor driven in an oscillatory-rotary manner about its fixed, preferably vertical, axis, for preferably biotechnological and pharmaceutical applications. By means of its process-intensifying properties for mixing, suspension, gaseous material transport, heat transfer, irradiation and particle retention, the applicability on the industrial scale is ensured. The reactor which succeeds without a shaft seal permits particularly robust production with respect to sterile technique with avoidance of cleaning and cleaning validation required when the reactor is constructed as a single-use reactor.Type: ApplicationFiled: April 23, 2007Publication date: July 16, 2009Applicant: Bayer Technology Services GmbHInventors: Jörg Kauling, Helmut Brod, Sebastian Schmidt, Martin Poggel, Björn Frahm, Reinhold Rose
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Publication number: 20090034358Abstract: A process and an apparatus for the bubble-free production of gas into liquids, in particular in biotechnology and especially of cell cultures, with gas exchange via one or more immersed membrane surfaces of any type (tubes, cylinders, etc.), with the membrane surfaces in rotary oscillating motion in the liquid.Type: ApplicationFiled: February 12, 2007Publication date: February 5, 2009Applicant: Bayer Technology Services GMBHInventors: Helmut Brod, Jorg Kauling, Bjorn Frahm, Reinhold Rose
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Publication number: 20070237024Abstract: Dynamic mixer having at least a housing, at least two rotating agitators, at least one of the agitators being a helical or anchor agitator arranged centrally in the housing, and at least one of the other agitators being an eccentrically arranged screw or blade agitator.Type: ApplicationFiled: July 2, 2005Publication date: October 11, 2007Applicant: Bayer Technology Services GmbHInventors: Helmut Brod, Stefanie Kohler, Reinhold Rose
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Patent number: 7074364Abstract: Modular device and method for carrying out experiments in parallel on process substances to develop technical methods, comprising at least a multiplicity of individual reactors which are controllable independently of one another said reactors being comprised of pressure-tight chambers having separable sample vessels, and optionally, stirring devices, heating instruments, cooling instruments, or both, a monitoring unit for monitoring or controlling at least the pressure and the temperature in the individual reactors, pressure-tight lids having independent feed lines and optionally independent discharge lines for individual process substances; a plurality of the lids being simultaneously sealable upon the rectors by a common sealing means (11).Type: GrantFiled: April 30, 2002Date of Patent: July 11, 2006Assignee: Bayer AktiengesellschaftInventors: Peter Jähn, Georg Wiessmeier, Bernhard Krumbach, Reinhold Rose, Thomas Siebert, Rainer Krautkrämer
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Publication number: 20050083782Abstract: A straight-arm paddle agitator is described for processing viscous reaction mixtures in vessels with a low filling level. The straight-arm paddle agitator is made from at least one shaft with a drive means for the rotation of the shaft and with an agitating beam fitted terminally to the shaft and is characterized in that the ends of the agitating beam are each provided with a helical segment which is positioned at an angle of 25° to 65°, preferably 30° to 60°, in relation to the shaft axis.Type: ApplicationFiled: October 13, 2004Publication date: April 21, 2005Inventors: Reinhold Gronau, Reinhold Rose, Thomas Herweg
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Patent number: 6627174Abstract: An axial conveyor is described, in particular for conveying gas/liquid dispersions, wherein the conveying elements comprise a wall-sweeping edge pointing in the direction of the pressure side of the conveying elements. The axial conveyor is particularly suitable as a circulating member in loop reactors. A process comprising conveying gas/liquid dispersions as well as a process for carrying out chemical reactions directly reacting gas with gases not completely dissolved in a liquid medium, or optionally in the presence of finely divided solids, through the use of an axial conveyor, is also disclosed.Type: GrantFiled: January 22, 1998Date of Patent: September 30, 2003Assignee: Bayer AktiengesellschaftInventors: Helmut Judat, Wolfgang Hemmerle, Reinhold Rose
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Publication number: 20020172629Abstract: Modular device and method for carrying out experiments in parallel on process substances to develop technical methods, comprising at least a multiplicity of individual reactors which are controllable independently of one another said reactors being comprised of pressure-tight chambers having separable sample vessels, and optionally, stirring devices, heating instruments, cooling instruments, or both, a monitoring unit for monitoring or controlling at least the pressure and the temperature in the individual reactors, pressure-tight lids having independent feed lines and optionally independent discharge lines for individual process substances; a plurality of the lids being simultaneously sealable upon the rectors by a common sealing means (11).Type: ApplicationFiled: April 30, 2002Publication date: November 21, 2002Inventors: Peter Jahn, Georg Wiessmeier, Bernhard Krumbach, Reinhold Rose, Thomas Siebert, Rainer Krautkramer