Patents by Inventor Reinhold Schirmbeck

Reinhold Schirmbeck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Delivery of immunogenic molecules vis HBsAg particles
    Patent number: 7029680
    Abstract: Compositions of HBsAg particles having biologically active molecules contained in the particles, and methods of their use, e.g. in stimulating enhanced immune responses, are described. Antigenic peptides contained in HBsAg particles were found to produce a CTL response where none was elicited by the peptide alone. Encapsulation of immunostimulating molecules, such as cytokines, greatly enhanced the CTL response evoked by the HBsAg particles themselves.
    Type: Grant
    Filed: February 2, 1999
    Date of Patent: April 18, 2006
    Assignees: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Jörg Reimann, Yechezkel Barenholz, Dvorah Diminsky, Reinhold Schirmbeck
  • Combined dna/protein vaccine compositions
    Publication number: 20050129712
    Abstract: The present invention relates to a combined DNA/Protein antigen vaccine composition which includes nucleic acid molecules and a mineral-based, negatively charged adjuvant, so as to enhance the immunogenicity of the DNA vaccine efficiently, enhancing not only plasmid DNA vaccines but also providing a novel strategy for immunogenic, multivalent combined protein/DNA vaccine delivery. Preferred adjuvants are aluminum or calcium salts, in particular aluminum phosphate.
    Type: Application
    Filed: March 28, 2003
    Publication date: June 16, 2005
    Inventors: Hansjorg Reimann, Reinhold Schirmbeck, Erik Lindblad