Abstract: A dome-shaped chemical sensing probe comprises an optical fiber or may be mounted on an optical fiber. The probe has a chemically sensitive measuring material which exhibits a change in volume and/or a change in refractive index in the presence of a given chemical. The change in volume and/or refractive index gives a change in an optical path length through the probe which can be measured interferometrically.

Abstract: A method of fabricating a sensor probe comprises: placing the end of an optical fiber 10 in a polymerization space 2; applying a drop of hydrogel pre-gel solution 30 to the end of the fiber; exposing said pre-gel solution to an ultra-violet light source 24 to cause polymerization therein; and monitoring a light signal that has passed down said optical fiber 10 in order to monitor said polymerization.

Abstract: A dome-shaped chemical sensing probe comprises an optical fiber or may be mounted on an optical fiber. The probe has a chemically sensitive measuring material which exhibits a change in volume and/or a change in refractive index in the presence of a given chemical. The change in volume and/or refractive index gives a change in an optical path length through the probe which can be measured interferometrically.

Abstract: A method of fabricating a sensor probe comprises: placing the end of an optical fiber 10 in a polymerization space 2; applying a drop of hydrogel pre-gel solution 30 to the end of the fiber; exposing said pre-gel solution to an ultra-violet light source 24 to cause polymerization therein; and monitoring a light signal that has passed down said optical fiber 10 in order to monitor said polymerization.

Abstract: A chemical sensing probe comprises an optical fiber or may be mounted on an optical fiber. The probe has a chemically sensitive measuring material which exhibits a change in volume and/or a change in refractive index in the presence of a given chemical. The change in volume and/or refractive index gives a change in an optical path length through the probe which can be measured interferometrically.

Abstract: The invention relates to a method of diagnosing prostate cancer in a subject, which method comprises determining the concentration of a relevant biochemical marker in the periprostatic tissue or lymph nodes of said subject, also to methods which categorise a prostate tumour and/or identify a prostate tumour which has extended beyond the prostatic capsule; as well as to apparatus which is suitable for use in such methods.

Abstract: A dome-shaped chemical sensing probe comprises an optical fiber or may be mounted on an optical fiber. The probe has a chemically sensitive measuring material which exhibits a change in volume and/or a change in refractive index in the presence of a given chemical. The change in volume and/or refractive index gives a change in an optical path length through the probe which can be measured interferometrically.

Abstract: An apparatus for controlling the temperature of a part of a human or animal body 2 during a cryosurgical procedure is disclosed. The apparatus comprises a radiative energy transmitter 26 for radiating energy to a zone of the body 2 to be protected from excessive cooling. There is also provided a means 12 for controlling the energy radiated by said radiative energy transmitter 26. Preferably the radiative energy transmitter comprises an infra-red laser diode coupled to a diffuser 34 by an optical fibre 40.

Abstract: The invention relates to an insertion probe for sensing distributed temperature comprising a tube containing at least one optical fiber being inscribed with at least one Bragg grating, the tube being sealed at its distal end. The probe is characterized in that it consists of materials having low magnetic susceptibility. The invention also relates to the use of such a probe in cryosurgery to allow the use of magnetic resonance imaging.

Abstract: A body compatible fiber optic sensor probe for invasive medical use is provided. The probe includes at least one sensing location at which the fiber is configured to provide at least one detectable changeable optical property responsive to strain within the fiber, and at least one sensing element which undergoes a volumetric change in response to an in body parameter to be sensed. The sensing element is coupled to the fiber in such a way that the volumetric change induces strain within the fiber so as to vary the detectable optical property or properties.

Abstract: A chemical sensing probe comprises an optical fiber or may be mounted on an optical fiber. The probe has a chemically sensitive measuring material which exhibits a change in volume and/or a change in refractive index in the presence of a given chemical. The change in volume and/or refractive index gives a change in an optical path length through the probe which can be measured interferometrically.

Abstract: An apparatus for controlling the temperature of a part of a human or animal body 2 during a cryosurgical procedure is disclosed. The apparatus comprises a radiative energy transmitter 26 for radiating energy to a zone of the body 2 to be protected from excessive cooling. There is also provided a means 12 for controlling the energy radiated by said radiative energy transmitter 26. Preferably the radiative energy transmitter comprises an infra-red laser diode coupled to a diffuser 34 by an optical fibre 40.

Abstract: The invention relates to an insertion probe for sensing distributed temperature comprising a tube containing at least one optical fiber being inscribed with at least one Bragg grating, the tube being sealed at its distal end. The probe is characterized in that it consists of materials having low magnetic susceptibility. The invention also relates to the use of such a probe in cryosurgery to allow the use of magnetic resonance imaging.

Abstract: A body compatible fiber optic sensor probe for invasive medical use is provided. The probe includes at least one sensing location at which the fiber is configured to provide at least one detectable changeable optical property responsive to strain within the fiber, and at least one sensing element which undergoes a volumetric change in response to an in body parameter to be sensed. The sensing element is coupled to the fiber in such a way that the volumetric change induces strain within the fiber so as to vary the detectable optical property or properties.