Abstract: A system and method are provided for normalizing range in an optoacoustic imaging system. In an embodiment, the system includes adjustable amplifiers and a probe having an array of transducer elements, each of the adjustable amplifiers being associated with one or more of the transducer elements. The transducer elements are acoustically coupled with a surface of a volume. The gain on the adjustable amplifiers is changed as a function of the passage of time during a predetermined period of time after a pulse of light. A sinogram is recorded by sampling the adjustably amplified plurality of transducer elements for the predetermined period of time. The sinogram is processed by substantially reversing the changing step mathematically, and storing the results in an expanded dynamic range sinogram. The expanded dynamic range sinogram provides sufficient numeric precision to permit the reversal of the changing step without materially decreasing the dynamic range of the information in the sinogram.

Abstract: An optoacoustic system includes first and second light sources capable of generating pulse of light at first and second wavelengths, optical output control, first and second light sync detectors, and a combiner. A power meter that is calibrated to determine power at the first and second predominant wavelength measures power at the first wavelength after the first light sync is detected and measures power at the second wavelength after the second light sync is detected. The system includes a calibration mode wherein it reduces optical output of the first light source when the power measured by the power meter at the first wavelength after the first light sync is detected is above a first level, and reduces optical output of the second light source when the power measured by the power meter at the second wavelength after the second light sync is detected is above a second level.

Abstract: An optoacoustic system includes first and second light sources capable of generating pulse of light at first and second wavelengths, optical output control, first and second light sync detectors, and a combiner. A power meter that is calibrated to determine power at the first and second predominant wavelength measures power at the first wavelength after the first light sync is detected and measures power at the second wavelength after the second light sync is detected. The system includes a calibration mode wherein it reduces optical output of the first light source when the power measured by the power meter at the first wavelength after the first light sync is detected is above a first level, and reduces optical output of the second light source when the power measured by the power meter at the second wavelength after the second light sync is detected is above a second level.

Abstract: An optoacoustic system includes first and second light sources capable of generating pulse of light at first and second wavelengths, first and second electrically controlled optical attenuators, first and second light sync detectors, and a combiner. A power meter that is calibrated to determine power at the first and second predominant wavelength measures power at the first wavelength after the first light sync is detected and measures power at the second wavelength after the second light sync is detected. The system includes a calibration mode wherein it electrically attenuates the first optical attenuator when the power measured by the power meter at the first wavelength after the first light sync is detected is above a first level, and electrically attenuated the second optical attenuator when the power measured by the power meter at the second wavelength after the second light sync is detected is above a second level.

Abstract: A system and method are provided for normalizing range in an optoacoustic imaging system. In an embodiment, the system includes adjustable amplifiers and a probe having an array of transducer elements, each of the adjustable amplifiers being associated with one or more of the transducer elements. The transducer elements are acoustically coupled with a surface of a volume. The gain on the adjustable amplifiers is changed as a function of the passage of time during a predetermined period of time after a pulse of light. A sinogram is recorded by sampling the adjustably amplified plurality of transducer elements for the predetermined period of time. The sinogram is processed by substantially reversing the changing step mathematically, and storing the results in an expanded dynamic range sinogram. The expanded dynamic range sinogram provides sufficient numeric precision to permit the reversal of the changing step without materially decreasing the dynamic range of the information in the sinogram.

Abstract: An optoacoustic system includes first and second light sources capable of generating pulse of light at first and second wavelengths, first and second electrically controlled optical attenuators, first and second light sync detectors, and a combiner. A power meter that is calibrated to determine power at the first and second predominant wavelength measures power at the first wavelength after the first light sync is detected and measures power at the second wavelength after the second light sync is detected. The system includes a calibration mode wherein it electrically attenuates the first optical attenuator when the power measured by the power meter at the first wavelength after the first light sync is detected is above a first level, and electrically attenuated the second optical attenuator when the power measured by the power meter at the second wavelength after the second light sync is detected is above a second level.

Abstract: The present invention is a personal health monitoring system which interactively delivers treatment stimuli and compiles a chronological history of a patient's health. The invention includes personal health diaries for direct measurement of physiological measurement as well as collection subjective responses. The personal health diaries also deliver educational content and health related reminders. The personal health diaries are remotely configured to deliver patient specific display of the treatment information. Patient response information, timing signals are routinely transmitted to the central monitoring system. The central monitoring system is programmed to automatically alert caregivers and family members when responses fall outside patient defined normal ranges. Caregivers and family members can interactive with the central monitoring system to provide updated treatment information as well as personal inspirational content.