Abstract: There are many techniques for determining the route of a mobile terminal. Among these techniques, some can be used to estimate this route along roads in a transport network using signalling data. Regarding the cross-referencing of this information with transport network graphs to determine this route, it is known to use hidden Markov models (HMMs). When the position of the mobile terminal is obtained using data collected from the radio communication network to which the mobile terminal is attached, the routes taken by a mobile terminal determined using a HMM on the basis of this information are uncertain. The present method and device helps to overcome this limitation by using a likelihood map of support by a base station to calculate a probability of connection of the mobile terminal to a given base station.

Abstract: The present invention is directed to compositions and methods for the transdermal delivery of a pharmaceutically active compound. In some embodiments, the addition of inert pharmaceutical ingredients in place of a portion of adhesive in a transdermal patch formulation increases the rate of skin permeation of a pharmaceutical compound.

Abstract: The present invention is directed to compositions for the sustained delivery of an antibiotic, for example vancomycin, to achieve desirable release profiles. This application is also directed to methods of using the compositions and processes for manufacturing the compositions.