Patents by Inventor René Alexandre GALIEN

René Alexandre GALIEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS
    Publication number: 20230310433
    Abstract: The present invention discloses compounds according to Formula I: Wherein R1, L1, R2, L2, R3, Cy, and the subscript n are as defined herein. The present invention relates to compounds, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of allergic diseases, inflammatory diseases, metabolic diseases, autoinflammatory diseases, autoimmune diseases, proliferative diseases, transplantation rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IFN?, IL12 and/or IL23 by administering the compound of the invention.
    Type: Application
    Filed: December 27, 2022
    Publication date: October 5, 2023
    Inventors: Steven Emiel VAN DER PLAS, Oscar MAMMOLITI, Sebastien Laurent Xavier MARTINA, Pieter Isabelle Roger CLAES, Ghjuvanni Petru Diunisu COTI, Denis Maurice ANNOOT, Miriam LÓPEZ RAMOS, René Alexandre GALIEN, David AMANTINI, Réginald Christophe Xavier BRYS
  • Compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders
    Patent number: 11564923
    Abstract: The present invention discloses compounds according to Formula I: Wherein R1, L1, R2, L2, R3, Cy, and the subscript n are as defined herein. The present invention relates to compounds, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of allergic diseases, inflammatory diseases, metabolic diseases, autoinflammatory diseases, autoimmune diseases, proliferative diseases, transplantation rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IFN?, IL12 and/or IL23 by administering the compound of the invention.
    Type: Grant
    Filed: October 11, 2018
    Date of Patent: January 31, 2023
    Assignee: GALAPAGOS NV
    Inventors: Steven Emiel Van Der Plas, Oscar Mammoliti, Sébastien Laurent Xavier Martina, Pieter Isabelle Roger Claes, Ghjuvanni Petru Diunisu Coti, Denis Maurice Annoot, Miriam López Ramos, René Alexandre Galien, David Amantini, Reginald Christophe Xavier Brys
  • NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS
    Publication number: 20210169879
    Abstract: The present invention discloses compounds according to Formula I: Wherein R1, L1, R2, L2, R3, Cy, and the subscript n are as defined herein. The present invention relates to compounds, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of allergic diseases, inflammatory diseases, metabolic diseases, autoinflammatory diseases, autoimmune diseases, proliferative diseases, transplantation rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IFN?, IL12 and/or IL23 by administering the compound of the invention.
    Type: Application
    Filed: October 11, 2018
    Publication date: June 10, 2021
    Inventors: Steven Emiel VAN DER PLAS, Oscar MAMMOLITI, Sébastien Laurent Xavier MARTINA, Pieter Isabelle Roger CLAES, Ghjuvanni Petru Diunisu COTI, Denis Maurice ANNOOT, Miriam LÓPEZ RAMOS, René Alexandre GALIEN, David AMANTINI, Reginald Christophe Xavier BRYS
  • COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISEASES
    Publication number: 20190314382
    Abstract: The present invention relates to the use of compounds or pharmaceutical compositions comprising the same, and methods of treatment using the same, in the prophylaxis and/or treatment of alopecia areata, vitiligo, cutaneous lupus, lupus nephritis, giant cell arteritis, sarcoïdosis and/or sarcoïdosis-related conditions. In particular the compounds are JAK inhibitors.
    Type: Application
    Filed: November 9, 2017
    Publication date: October 17, 2019
    Inventors: Chantal Thérèse TASSET, Pille HARRISON, René Alexandre GALIEN, John Sargent SUNDY, John G. MCHUTCHISON, Thomas O'RIORDAN, Neelufar MOZAFFARIAN, Uptal Dinesh PATEL, Timothy R. WATKINS, David L. GOSSAGE