Patents by Inventor Rene Zurfluh

Rene Zurfluh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100048546
    Abstract: The present invention relates to a method of combating phytopathogenic disease on crop plants by applying to the crop plants and/or the locus thereof an effective amount of a combination of a) 2-[?-{[(?-methyl-3-trifluoromethyl-benzyl)imino]-oxy}-o-tolyl]-glyoxalic acid methyl ester-O methyloxime (I) and b) one or more other plant fungicides. These combinations exhibit synergistic fungicidal activity and are particularly effective in combating and/or preventing diseases of crop plants.
    Type: Application
    Filed: August 19, 2009
    Publication date: February 25, 2010
    Inventors: Renè Zurflüh, Neil Leadbitter
  • Publication number: 20090306061
    Abstract: A method of combating phytopathogenic diseases on crop plants which comprises applying to the crop plants or the locus thereof being infested with said phytopathogenic disease an effective amount of a combination of a) 2-[?-{[(?-methyl-3-trifluoromethyl-benzyl)imino]-oxy}-o-tolyl]-glyoxalic acid methyl ester-O methyloxime (I) in association with b) a broad variety of other plant fungicides is particularly effective in combating or preventing diseases of crop plants. These combinations exhibit synergistic fungicidal activity.
    Type: Application
    Filed: August 19, 2009
    Publication date: December 10, 2009
    Inventors: René Zurflüh, Neil Leadbitter
  • Publication number: 20060128698
    Abstract: The present invention relates to a method of combating phytopathogenic disease on crop plants by applying to the crop plants and/or the locus thereof an effective amount of a combination of a) 2-[?-{[(?-methyl-3-trifluoromethyl-benzyl)imino]-oxy}-o-tolyl]-glyoxalic acid methyl ester-O methyloxime (I) and b) one or more other plant fungicides. These combinations exhibit synergistic fungicidal activity and are particularly effective in combating and/or preventing diseases of crop plants.
    Type: Application
    Filed: February 7, 2006
    Publication date: June 15, 2006
    Inventors: Rene Zurfluh, Neil Leadbitter
  • Publication number: 20040077895
    Abstract: The present invention relates to a novel improved process and intermediates for the process of preparing the oxime intermediates of formula (II) wherein R1 is hydrogen, fluoro or chloro, and R2 is methyl, ethyl, methoxy, ethoxy, trifluoromethyl, trifluoromethoxy, cyano, fluoro, chloro or bromo. The novel process comprises diazotizing an aniline of formula (VI) reacting the resulting diazonium salt with isopropenylacetate of formula (X) and reacting the resulting ketone of formula (XI) with an organic nitrite in the presence of hydrogene chloride, and methylating the resulting ketooxime of formula (VIII) with a methylating agent and reacting the resulting O-methyl ketooxime of formula (IX) with hydroxylamine. The compounds of formula (II) are intermediates for highly active fungicides from the class of the atrobilurins.
    Type: Application
    Filed: October 15, 2003
    Publication date: April 22, 2004
    Inventors: Rudolf Waditschatka, Rene Zurfluh, Edward Kelsall, Hugo Ziegler, Linhua Wang
  • Publication number: 20040039220
    Abstract: The invention relates to a process for the preparation of compounds of the formula 1
    Type: Application
    Filed: August 19, 2003
    Publication date: February 26, 2004
    Inventors: Saleem Farooq, Stephan Trah, Hugo Ziegler, Rene Zurfluh
  • Patent number: 6664422
    Abstract: The present invention relates to a novel improved process and intermediates for the process of preparing the oxime intermediates of formula (II) wherein R1 is hydrogen, fluoro or chloro, and R2 is methyl, ethyl, methoxy, ethoxy, trifluoromethyl, trifluoromethoxy, cyano, fluoro, chloro or bromo. The novel process comprises diazotizing an aniline of formula (VI) reacting the resulting diazonium salt with isopropenylacetate of formula (X) and reacting the resulting ketone of formula (XI) with an organic nitrite in the presence of hydrogene chloride, and methylating the resulting ketooxime of formula (VIII) with a methylating agent and reacting the resulting O-methyl ketooxime of formula (IX) with hydroxylamine. The compounds of formula (II) are intermediates for highly active fungicides from the class of the strobilurins.
    Type: Grant
    Filed: August 13, 2001
    Date of Patent: December 16, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Rudolf Waditschatka, René Zurflüh, Edward Kelsall, Hugo Ziegler, Linhua Wang
  • Patent number: 6646151
    Abstract: The invention relates to a process for the preparation of compounds of the formula or, if appropriate, a tautomer thereof, in each case in the free form or in salt form, in which A, X, Y, Z, R2, R3, R4, R5, R7, R9 and n are as defined in claim 1 and the C═N double bond marked with E has the E configuration, which comprises a1) reacting either a compound of the formula (II) mentioned above with a compound of the formula (III) mentioned above, in which X1 is a leaving group, or a2) a compound of the formula (IV) mentioned above, if appropriate in the presence of a base, with a compound of the formula (V) mentioned above, or b1) reacting a compound of the formula (VI) mentioned above with a compound of the formula R7—A—X2 (VII), in which X2 is a leaving group, and either further reacting the compound thus obtainable, of the formula (IV), for example according to method a2), or b2) reacting it with hydroxylamine or a salt thereof, if appropriate in the presence of a basic or
    Type: Grant
    Filed: September 26, 2000
    Date of Patent: November 11, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Saleem Farooq, Stephan Trah, Hugo Ziegler, René Zurflüh
  • Publication number: 20020198181
    Abstract: A method of combating phytopathogenic diseases on crop plants which comprises applying to the crop plants or the locus thereof being infested with said phytopathogenic disease an effective amount of a combination of
    Type: Application
    Filed: July 24, 2002
    Publication date: December 26, 2002
    Inventor: Rene Zurfluh
  • Patent number: 6451855
    Abstract: The present invention provides a method of combating phytopathogenic disease on a crop plant which comprises applying to the crop plant and/or its locus an effective amount of a combination of 2-[&agr;-{[(&agr;-methyl-3-trifluoromethyl-benzyl)imino]-oxy}-o-tolyl]-glyoxalic acid methyl ester-O methyloxime (I) and at least one compound selected from a broad variety of other plant fungicides. The combinations exhibit synergistic fungicidal activity and are particularly effective in combating or preventing diseases of crop plants.
    Type: Grant
    Filed: January 28, 2002
    Date of Patent: September 17, 2002
    Assignee: Bayer AKtiengesellschaft
    Inventors: René Zurflüh, Neil Leadbitter
  • Publication number: 20020094982
    Abstract: A method of combating phytopathogenic diseases on crop plants which comprises applying to the crop plants or the locus thereof being infested with said phytopathogenic disease an effective amount of a combination of
    Type: Application
    Filed: January 28, 2002
    Publication date: July 18, 2002
    Inventors: Rene Zurfluh, Neil Leadbitter
  • Patent number: 6420423
    Abstract: Compounds of the formula: in which n, q, A, X, G, Y, Z, R, R2, R3, R4, R5, R7 and R9 are as defined in claim 1, and, where appropriate, E/Z isomers, E/Z isomer mixtures and/or tautomers thereof, in each case in the free form or in an agrochemically suitable salt form, can be used as agrochemical active compounds and can be prepared in a manner known per se.
    Type: Grant
    Filed: June 29, 1999
    Date of Patent: July 16, 2002
    Assignee: Bayer Aktiengesellschaft
    Inventors: Saleem Farooq, Stephan Trah, Hugo Ziegler, René Zurflüh, Alfons Pascual, Henry Szczepanski, Roger Graham Hall
  • Patent number: 6395761
    Abstract: A method of combating phytopathogenic diseases on crop plants which comprises applying to the crop plants or the locus thereof being infested with said phytopathogenic disease an effective amount of a combination of a) 2-[&agr;-{[(&agr;-methyl-3-trifluoromethyl-benzyl)imino]-oxy}-o-tolyl]-glyoxalic acid methyl ester-O methyloxime (I) in association with b) a broad variety of other plant fungicides is particularly effective in combating or preventing diseases of crop plants. These combinations exhibit synergistic fungicidal activity.
    Type: Grant
    Filed: December 2, 2000
    Date of Patent: May 28, 2002
    Assignee: Bayer Aktiengesellschaft
    Inventors: René Zurflüh, Neil Leadbitter
  • Patent number: 6372787
    Abstract: Compounds of formula I wherein A is a group OCHR4 or N═CR4; Y is O or NH, R1 is C1-C6-alkyl; R2 is C1-C6-alkyl or C1-C6-alkyl substituted by 1 to 5 fluorine atoms; R3 is C1-C6-alkyl, C1-C6-alkoxy, C3-C6-cycloalkyl, C3-C6-cycloalkoxy, C2-C6-alkenyl, C2-C6-alkenyloxy, C2-C6-alkinyl, C2-C6-alkinyloxy, C1-C6-alkoxycarbonyl, CN or halogen, aryl, hetaryl, heterocyclyl, aryloxy, hetaryloxy or heterocyclyloxy, whereby the above-mentioned groups, with the exception of CN and halogen, may be substituted by the same or different substituents; R4 is methyl, ethyl or cyclopropyl; R6 is hydrogen or methyl; have microbicidal, insecticidal and acaricidal activity, and may be used to control plant-pathogenic fungi, acarids and insects in agriculture and in the field of hygiene.
    Type: Grant
    Filed: September 27, 2000
    Date of Patent: April 16, 2002
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hugo Ziegler, René Zurflüh
  • Patent number: 6342633
    Abstract: Compounds of the formula I in which Y is hydrogen, C1-C4alkyl, C1-C4alkoxy, OH, CN, NO2, Si(CH3)3, CF3 or halogen, Z is a group a) R1 is hydrogen, C1-C4alkyl, C2-C4alkenyl, C2-C4alkynyl, C3-C6cycloalkyl, phenyl which is unsubstituted or at most trisubstituted by halogen, C1-C4alkyl, C1-C4alkoxy, C1-C4alkylthio, or benzyl which is unsubstituted or at most trisubstituted in the aromatic ring in the same manner, or is cyclopropylmethyl, C1-C4haloalkyl, C2-C5alkoxyalkyl, cyanomethyl, CO—R6, OH, NH2, C1-C4alkylamine or C1-C4alkoxycarbonyl-C1-C2alkyl; X is oxygen, sulfur or NR5; R2 is hydrogen, C1-C4alkyl, C2-C4alkenyl, C2-C4alkynyl, C3-C6cycloalkyl, C(O)R6, OH or C1-C4alkoxy, NH2 or C1-C4alkylamine; R5 is hydrogen, C1-C4alkyl, C2-C4alkenyl or C2-C4alkynyl; R6 is hydrogen, C114 C4alkyl, C1-C4haloalkyl, C1-C4alkoxy, C3-C6cycloalkyl, C1-C4alkoxycarbonyl or phenyl which is unsubstituted or at most trisubstituted; and in which R3 and R4 independently of one another are hy
    Type: Grant
    Filed: September 27, 2000
    Date of Patent: January 29, 2002
    Assignee: Bayer Aktiengesellschaft
    Inventor: René Zurflüh
  • Patent number: 6313166
    Abstract: Compounds of the formula I and the isomers thereof, in which either a) X is an N atom and Y is OR11 or N(R12)R13, or b) X is CH and Y is OR11, and in which furthermore: R11 is C1-C4alkyl; R12 and R13, independenty, are hydrogen or C1-C4alkyl; A is an O atom or the group NR4; and wherein R1, R2 and R3 are as defined herein, are pesticidal active ingredients. They can be used for pest control, in particular as microbicides, insecticides and acaricides in agriculture, horticulture and in the hygiene sector.
    Type: Grant
    Filed: June 22, 1999
    Date of Patent: November 6, 2001
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hugo Ziegler, Stephan Trah, Saleem Farooq, René Zurflüh
  • Patent number: 6235684
    Abstract: A method of combating phytopathogenic diseases on crop plants which comprises applying to the crop plants or the locus thereof being infested with said phytopathogenic disease an effective amount of a combination of a) a 2-(5-phenyl-3,6-diaza-2,7-dioxa-octa-3,5-dienyl)phenylacrylamide of formula I wherein R1 is hydrogen, fluoro or chloro, R2 is methyl, ethyl, trifluoromethyl, trifluoromethoxy, cyano, fluoro, chloro or bromo, with the proviso that R2 cannot be fluoro, chloro or bromo, when R1 is hydrogen; in association with b) a broad variety of otherplant fungicides is particularly effective in combating or preventing fungal diseases of crop plants. These combinations exhibit synergistic fungicidal activity.
    Type: Grant
    Filed: February 28, 2000
    Date of Patent: May 22, 2001
    Assignee: Novartis Crop Protection, Inc.
    Inventors: Gertrude Knauf-Beiter, René Zurflüh, Bettina Gsell
  • Publication number: 20010000339
    Abstract: A method of combating phytopathogenic diseases on crop plants which comprises applying to the crop plants or the locus thereof being infested with said phytopathogenic disease an effective amount of a combination of
    Type: Application
    Filed: December 2, 2000
    Publication date: April 19, 2001
    Inventors: Rene Zurfluh, Neil Leadbitter
  • Patent number: 6211240
    Abstract: Compounds of the formula I in which Y is hydrogen, C1-C4alkyl, C1-C4alkoxy, OH, CN, NO2, Si(CH3)3, CF3 or halogen, Z is a group a) R1 is hydrogen, C1-C4alkyl, C2-C4alkenyl, C2-C4-alkynyl, C3-C6cycloalkyl, phenyl which is unsubstituted or at most trisubstituted by halogen, C1-C4alkyl, C1-C4alkoxy, C1-C4alkylthio, or benzyl which is unsubstituted or at most trisubstituted in the aromatic ring in the same manner; or is cyclopropylmethyl, C1-C4haloalkyl, C2-C5alkoxyalkyl, cyanomethyl, CO—R6, OH, NH2, C1-C4alkylamine or C1-C4alkoxycarbonyl-C1-C2alkyl; X is oxygen, sulfur or NR5; R2 is hydrogen, C1-C4alkyl, C2-C4alkenyl, C2-C4alkynyl, C3-C6cycloalkyl, C(O)R6, OH or C1-C4alkoxy, NH2 or C1-C4alkylamine; R5 is hydrogen, C1-C4alkyl, C2-C4alkenyl or C2-C4alkynyl; R6 is hydrogen, C114 C4alkyl, C1-C4haloalkyl, C1-C4alkoxy, C3-C6cycloalkyl, C1-C4alkoxycarbonyl or phenyl which is unsubstituted or at most trisubstituted; and in which R3 and R4 independently of one another are h
    Type: Grant
    Filed: October 29, 1996
    Date of Patent: April 3, 2001
    Assignee: Novartis Corporation
    Inventor: René Zurflüh
  • Patent number: 6156923
    Abstract: The invention relates to a process for the preparation of compounds of the formula ##STR1## or, if appropriate, a tautomer thereof, in each case in the free form or in salt form, in whichA, X, Y, Z, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.7, R.sub.9 and n are as defined in claim 1 and the C.dbd.N double bond marked with E has the E configuration, which comprisesa1) reacting either a compound of the formula (II) mentioned above with a compound of the formula (III) mentioned above, in which X.sub.1 is a leaving group, ora2) a compound of the formula (IV) mentioned above, if appropriate in the presence of a base, with a compound of the formula (V) mentioned above, orb1) reacting a compound of the formula (VI) mentioned above with a compound of the formula R.sub.7 --A--X.sub.2 (VII), in which X.sub.
    Type: Grant
    Filed: December 6, 1996
    Date of Patent: December 5, 2000
    Assignee: Novartis Corporation
    Inventors: Saleem Farooq, Stephan Trah, Hugo Ziegler, Rene Zurfluh
  • Patent number: 6150386
    Abstract: Compounds of formula (I) and their possible isomers and isomer mixtures, in which (Z) is a group (a), (b), (c) or (d) and in which the other substituents are as defined herein.
    Type: Grant
    Filed: December 22, 1997
    Date of Patent: November 21, 2000
    Assignee: Novartis Crop Protection, Inc.
    Inventors: Stephan Trah, Rene Zurfluh