Patents by Inventor Ren-Ke Li

Ren-Ke Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210268152
    Abstract: The present disclosure relates to a biocompatible, electrically conductive membrane capable of carrying the electrical potential of a cardiac impulse. The present disclosure also relates to treatments using the electrically conductive polymer, such as for atrial fibrillation.
    Type: Application
    Filed: May 20, 2021
    Publication date: September 2, 2021
    Inventor: Ren-Ke LI
  • Patent number: 11052173
    Abstract: The present disclosure relates to a biocompatible, electrically conductive polymer capable of carrying the electrical potential of a cardiac impulse. The present disclosure also relates to treatments using the electrically conductive polymer, such as for atrial fibrillation.
    Type: Grant
    Filed: May 22, 2019
    Date of Patent: July 6, 2021
    Assignee: University Health Network
    Inventor: Ren-Ke Li
  • Publication number: 20210087336
    Abstract: The present disclosure relates to a biocompatible, electrically conductive biomaterial capable of carrying the electrical potential of a cardiac impulse. The biomaterial comprises a conductive polymer and a biocompatible component. The conductive polymer comprising an aminomethoxybenzoic acid (AMBA) polymer. The present disclosure also relates to treatments, uses and devices using the biocompatible, electrically conductive biomaterial.
    Type: Application
    Filed: July 27, 2018
    Publication date: March 25, 2021
    Inventor: Ren-Ke Li
  • Publication number: 20190336644
    Abstract: The present disclosure relates to a biocompatible, electrically conductive polymer capable of carrying the electrical potential of a cardiac impulse. The present disclosure also relates to treatments using the electrically conductive polymer, such as for atrial fibrillation.
    Type: Application
    Filed: May 22, 2019
    Publication date: November 7, 2019
    Inventor: Ren-Ke LI
  • Patent number: 10350237
    Abstract: A biocompatible, electrically conductive biomaterial capable of earn carrying the electrical potential of a cardiac impulse and comprising (1) a conductive polymer such as polyaniline, polypyrrole or polythiophene, and (ii) a biocompatible component such as a polysaccharide, a protein, or a polypeptide, in particular chitosan or gelatin, is described. The material can take the form of a hydrogel, membrane, sheet or mesh. It can be used to restore or improve electrical impulse propagation across damaged tissue or scar region of the myocardium, in particular in the ti treatment of myocardial infarction and arrhythmia.
    Type: Grant
    Filed: February 4, 2014
    Date of Patent: July 16, 2019
    Assignee: University Health Network
    Inventor: Ren-Ke Li
  • Publication number: 20150366900
    Abstract: A biocompatible, electrically conductive biomaterial capable of earn carrying the electrical potential of a cardiac impulse and comprising (1) a conductive polymer such as polyaniline, polypyrrole or polythiophene, and (ii) a biocompatible component such as a polysaccharide, a protein, or a polypeptide, in particular chitosan or gelatin, is described. The material can take the form of a hydrogel, membrane, sheet or mesh. It can be used to restore or improve electrical impulse propagation across damaged tissue or scar region of the myocardium, in particular in the ti treatment of myocardial infarction and arrhythmia.
    Type: Application
    Filed: February 4, 2014
    Publication date: December 24, 2015
    Inventor: Ren-Ke Li
  • Publication number: 20120164100
    Abstract: The present disclosure provides temperature sensitive hydrogels and block copolymers, processes for the production thereof, and therapeutic and research compositions employing these copolymers.
    Type: Application
    Filed: November 2, 2011
    Publication date: June 28, 2012
    Inventors: Ren-Ke Li, Faquan Zeng
  • Publication number: 20080159997
    Abstract: A method is provided for forming a graft in heart tissue which comprises the transplantation of cells chosen from cardiomyocytes, fibroblasts, smooth muscle cells, endothelial cells and skeletal myoblasts. The grafts are especially useful in treating scar tissue on the heart.
    Type: Application
    Filed: August 10, 2007
    Publication date: July 3, 2008
    Applicant: Genzyme Corporation
    Inventors: Donald A. G. Mickle, Ren-Ke Li, Richard D. Weisel
  • Publication number: 20070031389
    Abstract: A method is provided for forming a graft in heart tissue which comprises the transplantation of cells chosen from cardiomyocytes, fibroblasts, smooth muscle cells, endothelial cells and skeletal myoblasts. The grafts are especially useful in treating scar tissue on the heart.
    Type: Application
    Filed: October 13, 2006
    Publication date: February 8, 2007
    Applicant: Genzyme Corporation
    Inventors: Donald Mickle, Ren-Ke Li, Richard Weisel
  • Patent number: 7067121
    Abstract: A method is provided for forming a graft in heart tissue which comprises the transplantation of cells chosen from cardiomyocytes, fibroblasts, smooth muscle cells, endothelial cells and skeletal myoblasts. The grafts are especially useful in treating scar tissue on the heart.
    Type: Grant
    Filed: August 23, 2004
    Date of Patent: June 27, 2006
    Assignee: Genzyme Corporation
    Inventors: Donald A. G. Mickle, Ren-Ke Li, Richard D. Weisel
  • Publication number: 20060093587
    Abstract: A method is provided for forming a graft in heart tissue which comprises the transplantation of cells chosen from cardiomyocytes, fibroblasts, smooth muscle cells, endothelial cells and skeletal myoblasts. The grafts are especially useful in treating scar tissue on the heart.
    Type: Application
    Filed: December 6, 2005
    Publication date: May 4, 2006
    Applicant: Genzyme Corporation
    Inventors: Donald Mickle, Ren-Ke Li, Richard Weisel
  • Publication number: 20050031600
    Abstract: The invention features methods and compositions for treating damaged or scarred myocardial tissue, by transplanting mesenchymal stem cells into the damaged or scarred tissue.
    Type: Application
    Filed: September 15, 2004
    Publication date: February 10, 2005
    Applicant: Genzyme Corporation
    Inventors: Donald Mickle, Ren-Ke Li, Richard Weisel
  • Publication number: 20050025749
    Abstract: A method is provided for forming a graft in heart tissue which comprises the transplantation of cells chosen from cardiomyocytes, fibroblasts, smooth muscle cells, endothelial cells and skeletal myoblasts. The grafts are especially useful in treating scar tissue on the heart.
    Type: Application
    Filed: August 23, 2004
    Publication date: February 3, 2005
    Applicant: Genzyme Corporation
    Inventors: Donald Mickle, Ren-Ke Li, Richard Weisel
  • Publication number: 20040071669
    Abstract: A method is provided for forming a graft in heart tissue which comprises the transplantation of cells chosen from cardiomyocytes, fibroblasts, smooth muscle cells, endothelial cells and skeletal myoblasts. The grafts are especially useful in treating scar tissue on the heart.
    Type: Application
    Filed: November 17, 2003
    Publication date: April 15, 2004
    Applicant: Genzyme Corporation
    Inventors: Donald A.G. Mickle, Ren-Ke Li, Richard D. Weisel
  • Patent number: 6682730
    Abstract: A method is provided for forming a graft in heart tissue which comprises the transplantation of cells chosen from cardiomyocytes, fibroblasts, smooth muscle cells, endothelial cells and skeletal myoblasts. The grafts are especially useful in treating scar tissue on the heart.
    Type: Grant
    Filed: January 29, 2002
    Date of Patent: January 27, 2004
    Assignee: Genzyme Corporation
    Inventors: Donald A. G. Mickle, Ren-Ke Li, Richard D. Weisel
  • Patent number: 6579523
    Abstract: A method is provided for forming a graft in heart tissue which comprises the transplantation of cells chosen from cardiomyocytes, fibroblasts, smooth muscle cells, endothelial cells and skeletal myoblasts. The grafts are especially useful in treating scar tissue on the heart.
    Type: Grant
    Filed: August 8, 2000
    Date of Patent: June 17, 2003
    Assignee: Genzyme Corporation
    Inventors: Donald A. G. Mickle, Ren-Ke Li, Richard D. Weisel
  • Publication number: 20020127210
    Abstract: A method is provided for forming a graft in heart tissue which comprises the transplantation of cells chosen from cardiomyocytes, fibroblasts, smooth muscle cells, endothelial cells and skeletal myoblasts. The grafts are especially useful in treating scar tissue on the heart.
    Type: Application
    Filed: January 29, 2002
    Publication date: September 12, 2002
    Inventors: Donald A. G. Mickle, Ren-Ke Li, Richard D. Weisel
  • Patent number: 6110459
    Abstract: A method is provided for forming a graft in heart tissue which comprises the transplantation of cells chosen from cardiomyocytes, fibroblasts, smooth muscle cells, endothelial cells and skeletal myoblasts. The grafts are especially useful in treating scar tissue on the heart. Also provided is a method of isolating and culturing cardiomyocytes for use in such grafts.
    Type: Grant
    Filed: May 28, 1997
    Date of Patent: August 29, 2000
    Inventors: Donald A. G. Mickle, Ren-Ke Li, Richard D. Weisel
  • Patent number: 6099832
    Abstract: A method is provided for forming a graft in heart tissue which comprises the transplantation of cells chosen from cardiomyocytes, fibroblasts, smooth muscle cells, endothelial cells and skeletal myoblasts. The grafts are especially useful in treating scar tissue on the heart.
    Type: Grant
    Filed: June 19, 1998
    Date of Patent: August 8, 2000
    Assignee: Genzyme Corporation
    Inventors: Donald A. G. Mickle, Ren-Ke Li, Richard D. Weisel