Patents by Inventor René Mönnikes

René Mönnikes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3-(5-fluoroindolyl)-4-arylmaleimide compounds and their use in tumor treatment
    Patent number: 11045449
    Abstract: The present invention relates to 3-(5-fluoroindolyl)-4-arylmaleimide compounds and pharmaceutical compositions containing them. The compounds of the present invention are protein kinases (GSK-3beta, VEGFR-2 and FLT-3) with antineoplastic activity. They can therefore be used for the treatment or prevention of tumors, in particular solid tumors.
    Type: Grant
    Filed: December 28, 2016
    Date of Patent: June 29, 2021
    Assignees: JOHANNES GUTENBERG-UNIVERSITÄT MAINZ, UNIVERSITÄTSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAT MAINZ
    Inventors: Markus Möhler, Annett Maderer, Gerd Dannhardt, Christopher Ganser, Eva Lauermann, René Mönnikes
  • 3-(5-Fluoroindolyl)-4-arylmaleimide Compounds and their Use in Tumor Treatment
    Publication number: 20200253930
    Abstract: The present invention relates to 3-(5-fluoroindolyl)-4-arylmaleimide compounds and pharmaceutical compositions containing them. The compounds of the present invention are protein kinases (GSK-3beta, VEGFR-2 and FLT-3) with antineoplastic activity. They can therefore be used for the treatment or prevention of tumors, in particular solid tumors.
    Type: Application
    Filed: December 28, 2016
    Publication date: August 13, 2020
    Inventors: Markus Möhler, Annett Maderer, Gerd Dannhardt, Christopher Ganser, Eva Lauermann, René Mönnikes