Patents by Inventor Ren-Shiang Chen

Ren-Shiang Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptides and regulation of calcium channels
    Patent number: 8299211
    Abstract: Calcium channels can be regulated by natural gamma proteins. Herein we disclose embodiments of compositions and methods, particularly involving short peptides which are capable of regulating calcium channel function. Certain short peptides which can inhibit calcium current have structural features from the first transmembrane domain of gamma6 such as a GxxxA motif and adjoining aliphatic residues. In embodiments the peptide compositions and methods are capable of selective efficacy for low voltage-activated calcium channels, such as LVA channel Cav3.1, versus high voltage-activated channels.
    Type: Grant
    Filed: April 24, 2009
    Date of Patent: October 30, 2012
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Philip M. Best, Ren-Shiang Chen, Zuojun Lin, Thomas Garcia
  • PEPTIDES AND REGULATION OF CALCIUM CHANNELS
    Publication number: 20090325887
    Abstract: Calcium channels can be regulated by natural gamma proteins. Herein we disclose embodiments of compositions and methods, particularly involving short peptides which are capable of regulating calcium channel function. Certain short peptides which can inhibit calcium current have structural features from the first transmembrane domain of gamma6 such as a GxxxA motif and adjoining aliphatic residues. In embodiments the peptide compositions and methods are capable of selective efficacy for low voltage-activated calcium channels, such as LVA channel Cav3.1, versus high voltage-activated channels.
    Type: Application
    Filed: April 24, 2009
    Publication date: December 31, 2009
    Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
    Inventors: Philip M. BEST, Ren-Shiang Chen, Zuojun Lin, Thomas Garcia