Patents by Inventor Renata WATANABE DA COSTA

Renata WATANABE DA COSTA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds, process for obtaining the compounds, pharmaceutical composition, use of the compounds and method for treating psychiatric disorders and/or sleep disorders
    Patent number: 11091445
    Abstract: The present disclosure relates to novel and inventive pharmacologically active benzimidazole derivative compounds, which surprisingly have high affinity for melatonin MT1 and MT2 receptors and low affinity for CYP450 complex enzymes, specially CYP1A2. The present invention also relates to novel and inventive routes of synthesis of these compounds, pharmaceutical compositions comprising the compounds and the use of these compounds in the treatment of individuals affected by psychiatric disorders and/or sleep disorders related to these receptors (specially depression, anxiety, circadian cycle disorders), in addition to a process for producing the composition.
    Type: Grant
    Filed: May 13, 2020
    Date of Patent: August 17, 2021
    Assignee: ACHÉ LABORATÓRIOS FARMACÊUTICOS S.A.
    Inventors: Cristiano Ruch Werneck Guimarães, Hatylas Felype Zaneti De Azevedo, Alessandra Mascarello, Renata Watanabe Da Costa, Valter Freire Torres Russo, Elisa Mannochio De Souza Russo
  • Compounds, process for obtaining the compounds, pharmaceutical composition, use of the compounds and method for treating psychiatric disorders and/or sleep disorders
    Patent number: 10781182
    Abstract: The present invention relates to novel and inventive pharmacologically active benzimidazole derivative compounds, which surprisingly have high affinity for melatonin MT1 and MT2 receptors and low affinity for CYP450 complex enzymes, specially CYP1A2. The present invention also relates to novel and inventive routes of synthesis of these compounds, pharmaceutical compositions comprising the compounds and the use of these compounds in the treatment of individuals affected by psychiatric disorders and/or sleep disorders related to these receptors (specially depression, anxiety, circadian cycle disorders), in addition to process for producing the composition.
    Type: Grant
    Filed: October 23, 2017
    Date of Patent: September 22, 2020
    Assignee: ACHÉ LABORATÓRIOS FARMACÊUTICOS S.A.
    Inventors: Cristiano Ruch Werneck Guimarães, Hatylas Felype Zaneti De Azevedo, Alessandra Mascarello, Renata Watanabe Da Costa, Valter Freire Torres Russo, Elisa Mannochio De Souza Russo
  • COMPOUNDS, PROCESS FOR OBTAINING THE COMPOUNDS, PHARMACEUTICAL COMPOSITION, USE OF THE COMPOUNDS AND METHOD FOR TREATING PSYCHIATRIC DISORDERS AND/OR SLEEP DISORDERS
    Publication number: 20200277265
    Abstract: The present disclosure relates to novel and inventive pharmacologically active benzimidazole derivative compounds, which surprisingly have high affinity for melatonin MT1 and MT2 receptors and low affinity for CYP450 complex enzymes, specially CYP1A2. The present invention also relates to novel and inventive routes of synthesis of these compounds, pharmaceutical compositions comprising the compounds and the use of these compounds in the treatment of individuals affected by psychiatric disorders and/or sleep disorders related to these receptors (specially depression, anxiety, circadian cycle disorders), in addition to a process for producing the composition.
    Type: Application
    Filed: May 13, 2020
    Publication date: September 3, 2020
    Inventors: Cristiano RUCH WERNECK GUIMARÃES, Hatylas FELYPE ZANETI DE AZEVEDO, Alessandra MASCARELLO, Renata WATANABE DA COSTA, Valter FREIRE TORRES RUSSO, Elisa MANNOCHIO DE SOUZA RUSSO
  • COMPOUNDS, PROCESS FOR OBTAINING THE COMPOUNDS, PHARMACEUTICAL COMPOSITION, USE OF THE COMPOUNDS AND METHOD FOR TREATING PSYCHIATRIC DISORDERS AND/OR SLEEP DISORDERS
    Publication number: 20190270711
    Abstract: The present invention relates to novel and inventive pharmacologically active benzimidazole derivative compounds, which surprisingly have high affinity for melatonin MT1 and MT2 receptors and low affinity for CYP450 complex enzymes, specially CYP1A2. The present invention also relates to novel and inventive routes of synthesis of these compounds, pharmaceutical compositions comprising the compounds and the use of these compounds in the treatment of individuals affected by psychiatric disorders and/or sleep disorders related to these receptors (specially depression, anxiety, circadian cycle disorders), in addition to process for producing the composition.
    Type: Application
    Filed: October 23, 2017
    Publication date: September 5, 2019
    Inventors: Cristiano RUCH WERNECK GUIMARÃES, Hatylas FELYPE ZANETI DE AZEVEDO, Alessandra MASCARELLO, Renata WATANABE DA COSTA, Valter FREIRE TORRES RUSSO, Elisa MANNOCHIO DE SOUZA RUSSO