Patents by Inventor Renate Zwijsen

Renate Zwijsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Interaction between cyclin D1 and steroid receptor co-activators and uses thereof in assays
    Patent number: 7012128
    Abstract: The present invention relates to the finding that cyclin D1 interacts in a ligand-independent fashion with coactivators of the SRC-1 family. The direct interaction of cyclin D1 enhances estrogen receptor (ER) mediated transcription and provides a novel target for the development of assays for substances which modulate the cell cycle. The invention provides assay methods for the prevention of growth of tumors, for assays for compounds useful in the prevention of tumors and compounds obtainable by such assays.
    Type: Grant
    Filed: September 14, 2001
    Date of Patent: March 14, 2006
    Assignee: TopoTarget UK Limited
    Inventors: René Bernards, Renate Zwijsen
  • Interaction between cyclin D1 and steroid receptor co-activators and uses thereof in assays
    Publication number: 20020177177
    Abstract: The present invention relates to the finding that cyclin D1 interacts in a ligand-independent fashion with coactivators of the SRC-1 family. The direct interaction of cyclin D1 enhances estrogen receptor (ER) mediated transcription and provides a novel target for the development of assays for substances which modulate the cell cycle. The invention provides assay methods for the prevention of growth of tumors, for assays for compounds useful in the prevention of tumors and compounds obtainable by such assays.
    Type: Application
    Filed: September 14, 2001
    Publication date: November 28, 2002
    Applicant: Prolifix Limited
    Inventors: Rene Bernards, Renate Zwijsen
  • Interaction between cyclin D1 and steroid receptor coactivators and users thereof in assays
    Patent number: 6350572
    Abstract: The present invention relates to the finding that cyclin D1 interacts in a ligand-independent fashion with coactivators of the SRC-1 family. The direct interaction of cyclin D1 enhances estrogen receptor (ER) mediated transcription and provides a novel target for the development of assays for substances which modulate the cell cycle. The invention provides assay methods for the prevention of growth of tumours, for assays for compounds useful in the prevention of tumours and compounds obtainable by such assays.
    Type: Grant
    Filed: April 30, 1999
    Date of Patent: February 26, 2002
    Assignee: Prolifix Limited
    Inventors: René Bernards, Renate Zwijsen