Patents by Inventor Renaud Robert

Renaud Robert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of benzo[c]quinolizinium derivatives for the treatment of diseases that are linked to smooth muscle cell constriction
    Patent number: 7897610
    Abstract: The invention relates to the use of benzo[c]quinolizinium derivatives for treating diseases that are linked to smooth muscle cell constriction, such as hypertension and asthma.
    Type: Grant
    Filed: June 5, 2003
    Date of Patent: March 1, 2011
    Assignees: Centre National de la Recherche Scientifique, Universite de Poitiers
    Inventors: Frédéric Becq, Renaud Robert, Laurence Pignoux, Christian Rogier, Yvette Mettey, Jean Michel Vierfond, Michel Joffre, Cécile Marivingt-Mounir
  • SCREENING ASSAY TO IDENTIFY CORRECTORS OF PROTEIN TRAFFICKING DEFECTS
    Publication number: 20110009351
    Abstract: The present invention relates to a novel assay or screen for identifying compounds with potential therapeutic value for the treatment of protein trafficking diseases such as Cystic Fibrosis (CF) and nephrogenic diabetes insipidus (NDI). The usual approach involves expressing the mutant form of the gene in cells and assaying function in a multiwell format when cells are exposed to libraries of compounds. Although such functional assays are useful, they do not directly test the ability of a compound to correct defective trafficking of the protein. To address this a novel corrector screening assay for CF has been developed in which the appearance of the mutant protein at the cell surface is measured as the assay output. This assay was used to screen more than 3100 compounds. This novel screening approach to protein trafficking diseases is robust and general, and may enable the selection of molecules that can be translated rapidly to a clinical setting.
    Type: Application
    Filed: May 9, 2008
    Publication date: January 13, 2011
    Inventors: David Y. Thomas, John Hanrahan, Graeme Carlile, Renaud Robert
  • Use of benzo[c]quinolizinium derivatives for the treatment of diseases that are linked to smooth muscle cell constriction
    Publication number: 20050176747
    Abstract: The invention relates to the use of benzo[c]quinolizinium derivatives for treating diseases that are linked to smooth muscle cell constriction, such as hypertension and asthma.
    Type: Application
    Filed: June 5, 2003
    Publication date: August 11, 2005
    Inventors: Frederic Becq, Renaud Robert, Laurence Pignoux, Christian Rogier, Yvette Mettey, Jean Vierfond, Michel Joffre, Cecile Marivingt-Mounir