Patents by Inventor Rene Braeckman

Rene Braeckman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of reducing apolipoprotein C-III
    Patent number: 10166209
    Abstract: In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
    Type: Grant
    Filed: December 23, 2015
    Date of Patent: January 1, 2019
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventors: Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Joseph S. Zakrzewski
  • STABLE PHARMACEUTICAL COMPOSITION AND METHODS OF USING SAME
    Publication number: 20180280334
    Abstract: The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
    Type: Application
    Filed: June 4, 2018
    Publication date: October 4, 2018
    Inventors: Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
  • METHODS OF TREATING HYPERTRIGLYCERIDEMIA
    Publication number: 20180185320
    Abstract: In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
    Type: Application
    Filed: February 28, 2018
    Publication date: July 5, 2018
    Inventors: Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
  • Stable pharmaceutical composition and methods of using same
    Patent number: 10010517
    Abstract: The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
    Type: Grant
    Filed: January 25, 2017
    Date of Patent: July 3, 2018
    Assignee: AMARIN PHARMACEUTICALS IRELAND LIMITED
    Inventors: Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
  • COMPOSITIONS AND METHODS FOR LOWERING LEVELS OF HIGH-SENSITIVITY C-REACTIVE PROTEIN (HS-CRP) IN A SUBJECT
    Publication number: 20180042883
    Abstract: The present disclosure provides methods for treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof. In some embodiments, the method comprises lowering high sensitivity CRP (hs-CRP) levels in a subject including, for example, a subject with a HbA1c value of about 5.00%-8.50% or at least about 6.8%.
    Type: Application
    Filed: October 24, 2017
    Publication date: February 15, 2018
    Inventors: Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
  • METHODS OF TREATING MIXED DYSLIPIDEMIA
    Publication number: 20180042880
    Abstract: The present disclosure relates to, inter alia, methods of treating mixed dyslipidemia with ethyl eicosapentaenoate.
    Type: Application
    Filed: October 5, 2017
    Publication date: February 15, 2018
    Inventors: Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
  • CO-ADMINISTRATION OF ATORVASTATIN AND ETHYL EICOSAPENTAENOIC ACID OR A DERIVATIVE THEREOF
    Publication number: 20180015071
    Abstract: In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of reducing triglycerides in a subject on atorvastatin therapy, the method comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof
    Type: Application
    Filed: September 27, 2017
    Publication date: January 18, 2018
    Inventors: Rene Braeckman, William Stirtan, Paresh Soni
  • Methods of treating mixed dyslipidemia
    Patent number: 9855237
    Abstract: The present disclosure relates to, inter alia, methods of treating mixed dyslipidemia with ethyl eicosapentaenoate.
    Type: Grant
    Filed: May 5, 2015
    Date of Patent: January 2, 2018
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventors: Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
  • Compositions and methods for lowering levels of high-sensitivity C-reactive protein (HS-CRP) in a subject
    Patent number: 9827219
    Abstract: The present disclosure provides methods for treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof. In some embodiments, the method comprises lowering high sensitivity CRP (hs-CRP) levels in a subject including, for example, a subject with a HbA1c value of about 5.00 %-8.50 % or at least about 6.8 %.
    Type: Grant
    Filed: January 7, 2013
    Date of Patent: November 28, 2017
    Assignee: AMARIN PHARMACEUTICALS IRELAND LIMITED
    Inventors: Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
  • COMPOSITIONS AND METHODS FOR REDUCING A FATTY ACID DESATURATION INDEX IN A SUBJECT IN NEED THEREOF
    Publication number: 20170143657
    Abstract: In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
    Type: Application
    Filed: February 6, 2017
    Publication date: May 25, 2017
    Inventors: Rene Braeckman, William Stirtan, Paresh Soni
  • STABLE PHARMACEUTICAL COMPOSITION AND METHODS OF USING SAME
    Publication number: 20170128402
    Abstract: The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
    Type: Application
    Filed: January 25, 2017
    Publication date: May 11, 2017
    Inventors: Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
  • Compositions and Methods for Lowering Triglycerides Without Raising LDL-C Levels in a Subject on Concomitant Statin Therapy
    Publication number: 20170128405
    Abstract: In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
    Type: Application
    Filed: January 20, 2017
    Publication date: May 11, 2017
    Inventors: Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
  • METHODS OF TREATING HYPERTRIGLYCERIDEMIA
    Publication number: 20170119722
    Abstract: In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
    Type: Application
    Filed: January 17, 2017
    Publication date: May 4, 2017
    Inventors: Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
  • Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy
    Patent number: 9585859
    Abstract: In various embodiments, the present invention provides methods of lowering triglycerides in subject on statin therapy and having baseline fasting triglycerides of about 200 mg/dl to less than 500 mg/dl, the methods comprising administering to the subject a composition comprising ethyl eicosapentaenoate.
    Type: Grant
    Filed: September 25, 2014
    Date of Patent: March 7, 2017
    Assignee: AMARIN PHARMACEUTICALS IRELAND LIMITED
    Inventors: Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
  • Stable pharmaceutical composition and methods of using same
    Patent number: 9585856
    Abstract: The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
    Type: Grant
    Filed: April 6, 2016
    Date of Patent: March 7, 2017
    Assignee: AMARIN PHARMACEUTICALS IRELAND LIMITED
    Inventors: Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
  • METHODS OF TREATING MIXED DYSLIPIDEMIA
    Publication number: 20170014366
    Abstract: The present disclosure relates to, inter alia, methods of treating mixed dyslipidemia with ethyl eicosapentaenoate.
    Type: Application
    Filed: September 22, 2016
    Publication date: January 19, 2017
    Inventors: Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
  • COMPOSITIONS AND METHODS FOR LOWERING TRIGLYCERIDES
    Publication number: 20160287546
    Abstract: In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
    Type: Application
    Filed: June 15, 2016
    Publication date: October 6, 2016
    Inventors: Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
  • Methods of reducing apolipoprotein C-III
    Patent number: 9452151
    Abstract: In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
    Type: Grant
    Filed: February 5, 2014
    Date of Patent: September 27, 2016
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventors: Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Joseph S. Zakrzewski
  • COMPOSITIONS AND METHODS FOR LOWERING TRIGLYCERIDES
    Publication number: 20160220522
    Abstract: In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
    Type: Application
    Filed: April 11, 2016
    Publication date: August 4, 2016
    Inventors: Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
  • STABLE PHARMACEUTICAL COMPOSITION AND METHODS OF USING SAME
    Publication number: 20160213636
    Abstract: The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
    Type: Application
    Filed: April 6, 2016
    Publication date: July 28, 2016
    Inventors: Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni