Patents by Inventor Rene Bruno

Rene Bruno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FIXED DOSING OF HER ANTIBODIES
    Publication number: 20230212311
    Abstract: The present invention concerns fixed dosing of HER antibodies, such as Pertuzumab.
    Type: Application
    Filed: June 15, 2022
    Publication date: July 6, 2023
    Applicant: Genentech, Inc.
    Inventors: DAVID E. ALLISON, RENE BRUNO, JIAN-FENG LU, CHEE M. NG
  • Pan-Indication Gradient Boosting Model Using Tumor Kinetics for Survival Prediction
    Publication number: 20220076836
    Abstract: A method for predicting a clinical outcome for a subject. Input data for a group of features is formed using baseline data and tumor kinetic data derived from longitudinal data for a set of variables for the subject, the set of variables including tumor size. A clinical outcome output that provides an indication of the clinical outcome for the subject is generated using a pan-indication model and the input data. The pan-indication model includes a gradient boosting decision tree-based ensemble machine learning algorithm.
    Type: Application
    Filed: September 8, 2021
    Publication date: March 10, 2022
    Inventors: James Lu, Jin Yan Lin, Hui Min Phillis Chan, Rene Bruno
  • Reinforced exhaust casing and manufacturing method
    Patent number: 10746056
    Abstract: An exhaust casing of a turbine engine for an aircraft which extends along an axis and includes: a central hub, an annular outer shroud and arms which connect the central hub to the outer shroud, at least one yoke for attaching the exhaust casing to the turbine engine being located on the outer shroud and forming at least one lug extending in a plane perpendicular to the axis and protruding toward the exterior of the outer shroud. The outer shroud includes ribs which form a constant excess of the outer shroud, which are located on either side of the at least one lug of the at least one yoke, and which are aligned with the at least one lug.
    Type: Grant
    Filed: September 20, 2017
    Date of Patent: August 18, 2020
    Assignee: Safran Aircraft Engines
    Inventors: Benoit Argemiro Matthieu Debray, Jeremie Sylvain Bonnaudet, Gregory Ghosarossian-Prillieux, Nicolas Rene Bruno Michelidakis, Guillaume Sevi
  • FIXED DOSING OF HER ANTIBODIES
    Publication number: 20200239595
    Abstract: The present invention concerns fixed dosing of HER antibodies, such as Pertuzumab.
    Type: Application
    Filed: December 10, 2019
    Publication date: July 30, 2020
    Applicant: Genentech, Inc.
    Inventors: DAVID E. ALLISON, RENE BRUNO, JIAN-FENG LU, CHEE M. NG
  • FIXED DOSING OF HER ANTIBODIES
    Publication number: 20180327510
    Abstract: The present invention concerns fixed dosing of HER antibodies, such as Pertuzumab.
    Type: Application
    Filed: March 2, 2018
    Publication date: November 15, 2018
    Applicant: Genentech, Inc.
    Inventors: DAVID E. ALLISON, RENE BRUNO, JIAN-FENG LU, CHEE M. NG
  • REINFORCED EXHAUST CASING AND MANUFACTURING METHOD
    Publication number: 20180080345
    Abstract: The invention relates to an exhaust casing (10) of a turbine engine for an aircraft which extends along an axis and which comprises a central hub (20), an annular outer shroud (30) and arms (40) which connect the central hub (20) to the outer shroud (30), at least one yoke (50) for attaching the exhaust casing (10) to the turbine engine being located on the outer shroud (30) and forming at least one lug (51) extending in a plane perpendicular to the axis and protruding toward the exterior of said outer shroud (30), characterized in that the outer shroud (30) comprises ribs (60) which form a constant excess of said outer shroud (30), which are located on either side of said at least one lug (51) of said at least one yoke (50), and which are aligned with said at least one lug (51).
    Type: Application
    Filed: September 20, 2017
    Publication date: March 22, 2018
    Applicant: Safran Aircraft Engines
    Inventors: Benoit Argemiro Matthieu DEBRAY, Jeremie Sylvain BONNAUDET, Gregory GHOSAROSSIAN-PRILLIEUX, Nicolas Rene Bruno MICHELIDAKIS, Guillaume SEVI
  • FIXED DOSING OF HER ANTIBODIES
    Publication number: 20170037147
    Abstract: The present invention concerns fixed dosing of HER antibodies, such as Pertuzumab.
    Type: Application
    Filed: October 21, 2016
    Publication date: February 9, 2017
    Applicant: Genentech, Inc.
    Inventors: David E. Allison, Rene Bruno, Jian-Feng Lu, Chee M. Ng
  • FIXED DOSING OF HER ANTIBODIES
    Publication number: 20150093381
    Abstract: The present invention concerns fixed dosing of HER antibodies, such as Pertuzumab.
    Type: Application
    Filed: November 26, 2014
    Publication date: April 2, 2015
    Applicant: GENENTECH, INC.
    Inventors: David E. Allison, Rene Bruno, Jian-Feng Lu, Chee M. Ng
  • Fixed dosing of HER antibodies
    Patent number: 8404234
    Abstract: The present invention concerns fixed dosing of HER antibodies, such as Pertuzumab.
    Type: Grant
    Filed: October 9, 2008
    Date of Patent: March 26, 2013
    Assignee: Genentech, Inc.
    Inventors: David E. Allison, Rene Bruno, Jian-Feng Lu, Chee M. Ng
  • FIXED DOSING OF HER ANTIBODIES
    Publication number: 20090081223
    Abstract: The present invention concerns fixed dosing of HER antibodies, such as Pertuzumab.
    Type: Application
    Filed: October 9, 2008
    Publication date: March 26, 2009
    Applicant: Genentech, Inc.
    Inventors: David E. Allison, Rene Bruno, Jian-Feng Lu, Chee M. Ng
  • Fixed dosing of HER antibodies
    Patent number: 7449184
    Abstract: The present invention concerns fixed dosing of HER antibodies, such as Pertuzumab.
    Type: Grant
    Filed: June 15, 2005
    Date of Patent: November 11, 2008
    Assignee: Genentech, Inc.
    Inventors: David E. Allison, Rene Bruno, Jian-Feng Lu, Chee M. Ng
  • Fixed dosing of HER antibodies
    Publication number: 20060165702
    Abstract: The present invention concerns fixed dosing of HER antibodies, such as Pertuzumab.
    Type: Application
    Filed: June 15, 2005
    Publication date: July 27, 2006
    Inventors: David Allison, Rene Bruno, Jian-Feng Lu, Chee Ng