Patents by Inventor Rene Chen

Rene Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HETEROCYCLIC COMPOUNDS AND METHODS OF USE
    Publication number: 20250122222
    Abstract: The present disclosure provides compounds useful for the inhibition of KRAS. The compounds have a general Formula I: wherein the variables of Formula I are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, cancer.
    Type: Application
    Filed: August 10, 2022
    Publication date: April 17, 2025
    Applicant: AMGEN INC.
    Inventors: Michael M. YAMANO, Yunxiao LI, Primali Vasundera NAVARATNE, Jose M. MEDINA, Ning CHEN, Liping PETTUS, Rene RAHIMOFF, Xiaofen LI, John STELLWAGEN, Francesco MANONI, Kexue LI, Brian Alan LANMAN, Ryan Paul Wurz, Wei ZHAO, Huan RUI, Josephine ESHON
  • Heterocyclic Compounds and Methods of Use
    Publication number: 20250059205
    Abstract: The present disclosure provides compounds useful for the inhibition of KRAS G12D. The compounds have a general Formula I: (I) wherein the variables of Formula I are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, cancer.
    Type: Application
    Filed: April 28, 2022
    Publication date: February 20, 2025
    Applicant: AMGEN INC.
    Inventors: Brian Alan Lanman, Ryan Paul Wurz, Wei Zhao, Xiaofen Li, Michael M. Yamano, Yunxiao Li, Ning Chen, Birgitte Weinreich Husemoen, Sebastian Leth-Petersen, Jose M. Medina, Kexue Li, Liping Pettus, Rene Rahimoff, Primali Vasundera Navaratne, Huan Rui, Christopher P. Mohr
  • Heterocyclic Compounds and Methods of Use
    Publication number: 20250059179
    Abstract: The present disclosure provides compounds useful for the inhibition of KRAS G12D. The compounds have a general Formula I: (I) wherein the variables of Formula I are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, cancer.
    Type: Application
    Filed: April 28, 2022
    Publication date: February 20, 2025
    Applicant: AMGEN INC.
    Inventors: Brian Alan Lanman, Ryan Paul Wurz, Wei Zhao, Xiaofen Li, Michael M. Yamano, Yunxiao Li, Ning Chen, Sebastian Leth-Petersen, Kexue Li, Liping Pettus, Rene Rahimoff, Primali Vasundera Navaratne, Huan Rui
  • Compositions and methods for inhibiting expression of transthyretin
    Patent number: 12227744
    Abstract: The invention relates to a double-stranded ribonucleic acid (dsRNA) targeting a transthyretin (TTR) gene, and methods of using the dsRNA to inhibit expression of TTR.
    Type: Grant
    Filed: April 15, 2022
    Date of Patent: February 18, 2025
    Assignee: Alnylam Pharmaceuticals, Inc.
    Inventors: Dinah Wen-Yee Sah, Gregory Hinkle, Rene Alvarez, Stuart Milstein, Qingmin Chen
  • HETEROCYCLIC COMPOUNDS AND METHODS OF USE
    Publication number: 20250034167
    Abstract: The present disclosure provides compounds useful for the inhibition of KRAS G12D. The compounds have a general Formula (I): wherein the variables of Formula I are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, cancer.
    Type: Application
    Filed: August 10, 2022
    Publication date: January 30, 2025
    Applicant: AMGEN INC.
    Inventors: Michael M. YAMANO, Yunxiao LI, Primali Vasundera NAVARATNE, Jose M. MEDINA, Ning CHEN, Liping PETTUS, Rene RAHIMOFF, Xiaofen LI, John STELLWAGEN, Francesco MANONI, Kexue LI, Brian Alan LANMAN, Ryan Paul Wurz, Wei ZHAO, Huan RUI, Josephine ESHON
  • Control hub
    Patent number: D780605
    Type: Grant
    Filed: October 9, 2015
    Date of Patent: March 7, 2017
    Assignee: ecoVent Corp.
    Inventors: Rene Chen, Thomas Frey, Jordan B. Nollman, Matthew Reis Bettencourt, Benjamin G. Lenart, Alex Calachan, Nicholaus Ray Lancaster
  • Room sensor
    Patent number: D781725
    Type: Grant
    Filed: October 9, 2015
    Date of Patent: March 21, 2017
    Assignee: ecoVent Corp.
    Inventors: Rene Chen, Thomas Frey, Jordan B. Nollman, Matthew Reis Bettencourt, Benjamin G. Lenart, Alex Calachan, Nicholaus Ray Lancaster