Abstract: An apparatus comprising a monitor, a blood pressure measuring device, and a controller. The monitor is configured to estimate a blood pressure of a patient. The blood pressure measuring device is configured to measure a blood pressure of the patient. The controller is operatively coupled to the monitor and to the blood pressure measuring device. The controller is configured to cause the blood pressure measuring device to take a first blood pressure measurement of the patient in response to an estimated blood pressure deviating from a baseline. The controller is also configured to cause the blood pressure measuring device to take a second blood pressure measurement of the patient in response to an estimated blood pressure deviating from a second baseline different than the first baseline.

Abstract: A system for measuring ECG data and respiratory data for a patient. The system includes at least four ECG wires configured to communicate a first set of cardiac electrical activity from the patient. A respiratory wire distinct from the at least four ECG wires is configured to communicate respiratory electrical activity from the patient. An electronics device is electrically coupled to the at least four ECG wires and to the respiratory wire. The electronics device is configured to measure the ECG data based on the first set of cardiac electrical activity from the at least four ECG wires, and to measure the respiratory data based on the respiratory electrical activity from the respiratory wire.

Abstract: A method of measuring noninvasive blood pressure includes determining a window for pulse detection for a patient, receiving a pressure signal measured from a measure sensor in a blood pressure cuff, and setting a pulse detection period for each heart beat based on the window and a heart beat indicator indicating at least one heart beat time for the patient. The pressure signal is then examined within each pulse detection period to identify a pressure peak therein. A blood pressure for the patient is determined based on the pressure peaks detected in the pressure signal.

Abstract: A method, device, and computer program product for managing alarms during a care process are disclosed. Care is provided to a subject according to settings of at least one care device and physiological parameters obtained from the subject are monitored, wherein the monitoring comprises triggering an alarm in response to detection of an alarm event. To enable smooth transfer from an alarm event to normal monitoring state, at least one available control option is determined for recovering from the alarm event. A user is prompted to select one of the at least one available control option, thereby to obtain a user-selected control option and the settings of the at least one care device are adjusted according to the user-selected control option.

Abstract: A method, device, and computer program product for improving accuracy of a respiratory gas measurement from a subject ventilated at a predetermined respiration rate through a ventilator. A respiratory gas measurement value is acquired within a first expiration period of the subject, thereby to obtain a first measurement value. The ventilator is paused for a pause period within a second expiration period of the subject and a respiratory gas measurement is performed within the pause period, thereby to obtain a second measurement value. A correction factor is then determined based on the first measurement value and the second measurement value and the correction factor is employed to correct subsequent respiratory gas measurement values obtained from the subject at the predetermined respiration rate, thereby to improve the accuracy of the measurement.

Abstract: A method, device, and computer program product for monitoring clinical state of a subject are disclosed. To facilitate the manual adaptation of the care processes to the current state of a patient at least one input parameter is retrieved, wherein each input parameter is indicative of control applied to a respective physiological process of the subject. An output parameter is acquired for each of the at least one input parameter, thereby to obtain a parameter pair, wherein each input and output parameter is indicative of the respective physiological process. Each parameter pair is presented on a dedicated two-dimensional plot comprising a first axis representing respective input parameter and a second axis representing, respective output parameter, wherein the first axis is scaled according to the input operating range of the respective input parameter and the second axis is scaled according to the output operating range of the respective output parameter.

Abstract: A method, device, and computer program product for improving accuracy of a respiratory gas measurement from a subject ventilated at a predetermined respiration rate through a ventilator. A respiratory gas measurement value is acquired within a first expiration period of the subject, thereby to obtain a first measurement value. The ventilator is paused for a pause period within a second expiration period of the subject and a respiratory gas measurement is performed within the pause period, thereby to obtain a second measurement value. A correction factor is then determined based on the first measurement value and the second measurement value and the correction factor is employed to correct subsequent respiratory gas measurement values obtained from the subject at the predetermined respiration rate, thereby to improve the accuracy of the measurement.

Abstract: A method and apparatus for determining the presence or absence of a pulmonary embolism (PE) in a patient. The breathing gas CO2 partial pressure (PCO2) during the expiration of breathing gases by the patient, the end tidal (EtCO2), CO2 partial pressure, and the CO2 partial pressure (PaCO2) of the blood are measured. The volume (V) of breathing gases expired during the expiration of breathing gases by the patient is also measured and a relationship between changes in breathing gas CO2 partial pressure (PCO2) and changes in breathing gas volume (V) in an alveolar expiration phase of patient expiration is determined. The difference between the blood CO2 partial pressure (PaCO2) and the end expiration CO2 partial pressure is divided by the relationship between PCO2 and V produce a quantity which is compared to a threshold value. If the quantity is below the threshold value, the absence of a pulmonary embolism is indicated.

Abstract: A method, device, and computer program product for managing alarms during a care process are disclosed. Care is provided to a subject according to settings of at least one care device and physiological parameters obtained from the subject are monitored, wherein the monitoring comprises triggering an alarm in response to detection of an alarm event. To enable smooth transfer from an alarm event to normal monitoring state, at least one available control option is determined for recovering from the alarm event. A user is prompted to select one of the at least one available control option, thereby to obtain a user-selected control option and the settings of the at least one care device are adjusted according to the user-selected control option.

Abstract: The system and method includes a treatment device such as an anesthetic machine or IV, a monitor and a display configured to display real-time PK/PD data associated with an anesthetic agent administered to the patient. The system and method further includes a safety control means configured to control the display such that one of a basic display state, an interactive effects display state, and a display inhibited state is selected and displayed according to the anesthetic agents and levels of the same being administered to the patient.

Abstract: A system and method of modeling the pharmacodynamic effect of drugs delivered to a patient. The system includes a model database comprising a first drug interaction model and a second drug interaction model. A processing unit determines a first pharmacodynamic effect and a second pharmacodynamic effect and using a dominance rule to compare the first pharmacodynamic effect and a second pharmacodynamic effect to determine a dominant interaction model. A graphical display connected to the processing unit presents the determined dominant interaction model.

Abstract: The system and method includes a treatment device such as an anesthetic machine or IV, a monitor and a display configured to display real-time PK/PD data associated with an anesthetic agent administered to the patient. The system and method further includes a safety control means configured to control the display such that one of a basic display state, an interactive effects display state, and a display inhibited state is selected and displayed according to the anesthetic agents and levels of the same being administered to the patient.

Abstract: A graphical user interface for use by a clinician in the monitoring of the depth of the anesthesia of a patient. The graphical user interface comprising a drug library with data related to a plurality of anesthetic drugs, a drug administration window for displaying drug administration data, at least one window disposed for the display of a pharmacokinetic graph and a pharmacodynamic graph, and a scale selector comprising a first condition wherein the pharmacokinetic model and the pharmacodynamic models are displayed and a second condition where only the pharmacokinetic model is displayed.

Abstract: A graphical user interface for the documentation of an administered anesthetic drug and the display of an associated pharmacokinetic model and an associated pharmacodynamic model. The graphical user interface comprises a first window that displays the drug administration data, and a second window displaying a pharmacokinetic model and a pharmacodynamic model, the second window being separate and distinct from the first window. The pharmacokinetic model and the pharmacodynamic models are overlaid and displayed and the pharmacokinetic model and the pharmacodynamic model are based on the drug administration data displayed in the first window.

Abstract: A method and apparatus for determining the presence or absence of a pulmonary embolism (PE) in a patient. The breathing gas CO2 partial pressure (PCO2) during the expiration of breathing gases by the patient, the end tidal (EtCO2), CO2 partial pressure, and the CO2 partial pressure (PaCO2) of the blood are measured. The volume (V) of breathing gases expired during the expiration of breathing gases by the patient is also measured and a relationship between changes in breathing gas CO2 partial pressure (PCO2) and changes in breathing gas volume (V) in an alveolar expiration phase of patient expiration is determined. The difference between the blood CO2 partial pressure (PaCO2) and the end expiration CO2 partial pressure is divided by the relationship between PCO2 and V produce a quantity which is compared to a threshold value. If the quantity is below the threshold value, the absence of a pulmonary embolism is indicated.