Abstract: The present disclosure relates to hollow fiber tangential flow filter units, including hollow fiber tangential flow depth filter units, for various applications, including bioprocessing and pharmaceutical applications, systems employing such filters, and methods of filtration using the same.

Abstract: The present disclosure relates to spectroscopy with light emitting components including, e.g., UV and/or visible wavelength light, for various applications, including, e.g., chromatography, and more particularly, for a sampling device that facilitates spectroscopic measurements with a variable pathlength and methods for such a device. In an aspect, a device for measuring light absorbance of a sample may include a fluid conduit comprising a first portion, a midportion substantially perpendicular to the first portion, and a second portion substantially perpendicular to the midportion. A first probe may be within the midportion and substantially parallel with the midportion. The first probe may comprise a distal end. A light source may be operably coupled to the first probe. A detector may be aligned with the distal end of the first probe substantially perpendicular to the first probe at a pathlength from the distal end of the first probe.

Abstract: The invention relates to a device (10) for linking at least two electronic apparatuses (60), the device (10) comprising a first power supply connector (12), a first DC link connector (16), a second power supply connector (14), a second DC link connector (18), and an electronic apparatus connector (20), wherein the electronic apparatus connector (20) comprises power supply lines (24) and DC lines (22), wherein the first power supply connector (12) is electrically connected to the second power supply connector (14) and the power supply lines (24), wherein the first DC link connector (16) is electrically connected to the second DC link connector (18) and the DC lines (22), wherein the first power supply connector (12) is pluggable to a second power supply connector (14) of a further device (10) for linking at least two electronic apparatuses (60), wherein the first DC link connector (16) is pluggable to a second DC link connector (18) of a further device (10) for linking at least two electronic apparatuses (60).

Abstract: A method for the validation of physiological data, acquired in two or more parts of the human body by sensors connected to a medical device, for the statistical validation of the relationship among the signals retrieved by the medical devices, in order to select information that increases the accuracy of the study being carried out, with a high statistical certainty. The purpose of the actual invention is to make this statistically validated data available for use by protocols or reference values, according to the field of application, which increase accuracy of the studies being carried out.

Abstract: A method for the validation of physiological data, acquired in two or more parts of the human body by sensors connected to a medical device, for the statistical validation of the relationship among the signals retrieved by the medical devices, in order to select information that increases the accuracy of the study being carried out, with a high statistical certainty. The purpose of the actual invention is to make this statistically validated data available for use by protocols or reference values, according to the field of application, which increase accuracy of the studies being carried out.

Abstract: Cellular targets for anti-retroviral drug development are disclosed. The cellular targets comprise ATR kinase and its relevant substrates, based on the identification of the ATR kinase as required for the final step of retroviral DNA integration. Assays for identifying modulators of retroviral integration via the ATR kinase pathway are disclosed, as well as modulators identified by such assays. Pharmaceutical preparations and methods of their use in treating retroviral infection are also disclosed.

Abstract: A fuel injector for a gas turbine engine combustion chamber is disclosed. The fuel injector includes a first fuel supply line for running at idle speed, a second, main, fuel supply line for running at speeds up to full throttle, and first and second injection orifices with which the two fuel supply lines respectively communicate. The injection orifices are arranged in a ring and the first orifices occupy a sector of the ring.

Abstract: Cellular targets for anti-retroviral drug development are disclosed. The cellular targets comprise ATR kinase and its relevant substrates, based on the identification of the ATR kinase as required for the final step of retroviral DNA integration. Assays for identifying modulators of retroviral integration via the ATR kinase pathway are disclosed, as well as modulators identified by such assays. Pharmaceutical preparations and methods of their use in treating retroviral infection are also disclosed.

Abstract: The present invention relates to a fuel injector (100) for a gas turbine engine combustion chamber, comprising a first fuel supply line for running at idle speed, and a second, main, fuel supply line for running at speeds up to full throttle and first (112) and second (113) injection orifices with which the two fuel supply lines respectively communicate. The injector is one wherein the injection orifices (112, 113) are arranged in a ring, the first orifices occupying a sector of said ring.

Abstract: Cellular targets for anti-retroviral drug development are disclosed. The cellular targets comprise ATR kinase and its relevant substrates, based on the identification of the ATR kinase as required for the final step of retroviral DNA integration. Assays for identifying modulators of retroviral integration via the ATR kinase pathway are disclosed, as well as modulators identified by such assays. Pharmaceutical preparations and methods of their use in treating retroviral infection are also disclosed.

Abstract: The present invention provides a process for the spin dyeing of acrylic fibre obtained by spinning a collodion of a homopolymer or copolymer of acrylonitrile, in which the coloring agent comprises at least one nitrate of a cationic dyestuff; it also provides textile fibres based on a homopolymer or copolymer of acrylonitrile which have been dyed in accordance with such a process.