Patents by Inventor Rene J. Trabanino

Rene J. Trabanino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • System and methods for predicting transmembrane domains in membrane proteins and mining the genome for recognizing G-protein coupled receptors
    Patent number: 8370074
    Abstract: The invention provides computer-implemented methods and apparatus implementing a hierarchical protocol using multiscale molecular dynamics and molecular modeling methods to predict the presence of transmembrane regions in proteins, such as G-Protein Coupled Receptors (GPCR), and protein structural models generated according to the protocol. The protocol features a coarse grain sampling method, such as hydrophobicity analysis, to provide a fast and accurate procedure for predicting transmembrane regions. Methods and apparatus of the invention are useful to screen protein or polynucleotide databases for encoded proteins with transmembrane regions, such as GPCRs.
    Type: Grant
    Filed: October 27, 2009
    Date of Patent: February 5, 2013
    Assignee: California Institute of Technology
    Inventors: Rene J. Trabanino, Nagarajan Vaidehi, Spencer E. Hall, William A. Goddard, Wely Floriano
  • SYSTEM AND METHODS FOR PREDICTING TRANSMEMBRANE DOMAINS IN MEMBRANE PROTEINS AND MINING THE GENOME FOR RECOGNIZING G-PROTEIN COUPLED RECEPTORS
    Publication number: 20100299127
    Abstract: The invention provides computer-implemented methods and apparatus implementing a hierarchical protocol using multiscale molecular dynamics and molecular modeling methods to predict the presence of transmembrane regions in proteins, such as G-Protein Coupled Receptors (GPCR), and protein structural models generated according to the protocol. The protocol features a coarse grain sampling method, such as hydrophobicity analysis, to provide a fast and accurate procedure for predicting transmembrane regions. Methods and apparatus of the invention are useful to screen protein or polynucleotide databases for encoded proteins with transmembrane regions, such as GPCRs.
    Type: Application
    Filed: October 27, 2009
    Publication date: November 25, 2010
    Inventors: Rene J. TRABANINO, Nagarajan VAIDEHI, Spencer E. HALL, William A. Goddard, Wely FLORIANO