Abstract: The present invention is directed to a system and method for installing seals on support frames. The system comprises, generally, a seal supply system, a guiding mechanism and a sealing mechanism. The supply system comprises two bobbins around which are disposed the sealing elements. The guiding mechanism comprises a plurality of guiding drive wheels adapted to guide the support frames towards the sealing mechanism which is adapted to seal the sealing element to the support frame. The sealing mechanism is adapted to exert continuously a constant pressure on the sealing element allowing it to fit to the correspondent support frame once being introduced to the sealing mechanism.

Abstract: The present invention is directed to a system and method for installing seals on support frames. The system comprises, generally, a seal supply system, a guiding mechanism and a sealing mechanism. The supply system comprises two bobbins around which are disposed the sealing elements. The guiding mechanism comprises a plurality of guiding drive wheels adapted to guide the support frames towards the sealing mechanism which is adapted to seal the sealing element to the support frame. The sealing mechanism is adapted to exert continuously a constant pressure on the sealing element allowing it to fit to the correspondent support frame once being introduced to the sealing mechanism.

Abstract: Disclosed is the use of a HIF-? potentiating agent and a mobilizer of hematopoietic stem cells and/or progenitor cells in methods and compositions for mobilizing hematopoietic stem cell and progenitor cells from the bone marrow into the peripheral blood. The compositions and methods are particularly useful for stem cell transplantation and for treating or preventing immune deficiencies.