Patents by Inventor Rene Reinbigler
Rene Reinbigler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240010965Abstract: The present application relates to biotechnological fluid treating, such as biopharmaceutical liquids in order to obtain products such as monoclonal antibodies, vaccines or recombinant proteins, and particularly to a system for treating a biotechnical fluid, having a bioprocess machine and at least one bioprocess machine helper, configured to connect to each other and each comprising a controller, in turn comprising a machine-to-machine communication tool configured for connecting to a network.Type: ApplicationFiled: August 19, 2021Publication date: January 11, 2024Applicant: MERCK PATENT GMBHInventors: Rene REINBIGLER, Denis DUBRET, Steven MILLER
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Publication number: 20230340395Abstract: The present application relates to biotechnological fluid treating, such as biopharmaceutical liquids in order to obtain products such as monoclonal antibodies, vaccines or recombinant proteins, and particularly to a system for treating a biotechnical fluid, having a bioprocess machine and at least one bioprocess machine helper, configured to connect to each other and each comprising a controller, in turn comprising a machine-to-machine communication tool configured for connecting to a networkType: ApplicationFiled: August 19, 2021Publication date: October 26, 2023Applicant: MERCK PATENT GMBHInventors: Rene REINBIGLER, Denis DUBRET, Steven MILLER
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Publication number: 20230313114Abstract: The present application relates to biotechnological fluid treating, such as biopharmaceutical liquids in order to obtain products such as monoclonal antibodies, vaccines or recombinant proteins, and particularly to a system for treating a biotechnical fluid, having a bioprocess machine and at least one bioprocess machine helper, configured to connect to each other and each comprising a controller, in turn comprising a machine-to-machine communication tool configured for connecting to a network.Type: ApplicationFiled: August 19, 2021Publication date: October 5, 2023Applicant: MERCK PATENT GMBHInventors: Rene REINBIGLER, Denis DUBRET, Steve MILLER
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Patent number: 11511281Abstract: A fluid transfer device includes a syringe barrel having a chamber, a first plunger slidably movable inside the chamber, and a second plunger slidably movable inside the chamber. The distal end portion of the first plunger is engageable with the proximal end portion of the second plunger such that when the distal end portion of the first plunger and the proximal end portion of the second plunger are engaged, the second plunger is movable by the first plunger. A check valve may be incorporated into the distal end portion of the second plunger to allow a fluid to pass therethrough in a direction towards the proximal end portion of the second plunger and prevent a fluid to pass therethrough in a reverse direction. A fluid transfer assembly and a sampling method are also described.Type: GrantFiled: May 19, 2020Date of Patent: November 29, 2022Assignee: EMD Millipore CorporationInventors: Joseph Muldoon, Rene Reinbigler
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Patent number: 10766666Abstract: The invention concerns a device comprising a base (2) and a door (20), said device having a closed door position in which a circuit (8) of the device comprises a bag comprising two flexible films and connectors of the conveying network, and a press (9) comprising a first shell (16) disposed on a front face (5) of said base (2) and a second shell (17) disposed in said door (20); and a hinge system hinging said door (20) relative to said base (2), and disposed only on one side of said door (20) so as to form lateral clearances between said door (20) and said base (2) over the rest of a perimeter of said door (20).Type: GrantFiled: December 20, 2017Date of Patent: September 8, 2020Assignee: EMD Millipore CorporationInventors: Sebastien Cirou, Rene Reinbigler, Virginie Buisson, Jean-Louis Weissenbach
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Publication number: 20200276587Abstract: A fluid transfer device includes a syringe barrel having a chamber, a first plunger slidably movable inside the chamber, and a second plunger slidably movable inside the chamber. The distal end portion of the first plunger is engageable with the proximal end portion of the second plunger such that when the distal end portion of the first plunger and the proximal end portion of the second plunger are engaged, the second plunger is movable by the first plunger. A check valve may be incorporated into the distal end portion of the second plunger to allow a fluid to pass therethrough in a direction towards the proximal end portion of the second plunger and prevent a fluid to pass therethrough in a reverse direction. A fluid transfer assembly and a sampling method are also described.Type: ApplicationFiled: May 19, 2020Publication date: September 3, 2020Inventors: Joseph Muldoon, Rene Reinbigler
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Patent number: 10688495Abstract: A fluid transfer device includes a syringe barrel having a chamber, a first plunger slidably movable inside the chamber, and a second plunger slidably movable inside the chamber. The distal end portion of the first plunger is engageable with the proximal end portion of the second plunger such that when the distal end portion of the first plunger and the proximal end portion of the second plunger are engaged, the second plunger is movable by the first plunger. A check valve may be incorporated into the distal end portion of the second plunger to allow a fluid to pass therethrough in a direction towards the proximal end portion of the second plunger and prevent a fluid to pass therethrough in a reverse direction. A fluid transfer assembly and a sampling method are also described.Type: GrantFiled: October 14, 2015Date of Patent: June 23, 2020Assignee: EMD Millipore CorporationInventors: Joseph Muldoon, Rene Reinbigler
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Patent number: 10195605Abstract: The method comprises the step of forming pipes (12) by clamping a bag between shells (13, 14) and by injecting an inflating agent via an inflating connector. The circuit comprises a bag (126) and a press (10) comprising two shells (13, 14) clamping said bag in a state in which pipes (12) are formed between the films (25, 26) of the bag.Type: GrantFiled: May 23, 2016Date of Patent: February 5, 2019Assignee: EMD Millipore CorporationInventors: Rene Reinbigler, Jean-Louis Weissenbach
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Publication number: 20180214876Abstract: A fluid transfer device includes a syringe barrel having a chamber, a first plunger slidably movable inside the chamber, and a second plunger slidably movable inside the chamber. The distal end portion of the first plunger is engageable with the proximal end portion of the second plunger such that when the distal end portion of the first plunger and the proximal end portion of the second plunger are engaged, the second plunger is movable by the first plunger. A check valve may be incorporated into the distal end portion of the second plunger to allow a fluid to pass therethrough in a direction towards the proximal end portion of the second plunger and prevent a fluid to pass therethrough in a reverse direction. A fluid transfer assembly and a sampling method are also described.Type: ApplicationFiled: October 14, 2015Publication date: August 2, 2018Inventors: Joseph Muldoon, Rene Reinbigler
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Publication number: 20180111720Abstract: The invention concerns a device comprising a base (2) and a door (20), said device having a closed door position in which a circuit (8) of the device comprises a bag comprising two flexible films and connectors of the conveying network, and a press (9) comprising a first shell (16) disposed on a front face (5) of said base (2) and a second shell (17) disposed in said door (20); and a hinge system hinging said door (20) relative to said base (2), and disposed only on one side of said door (20) so as to form lateral clearances between said door (20) and said base (2) over the rest of a perimeter of said door (20).Type: ApplicationFiled: December 20, 2017Publication date: April 26, 2018Inventors: Sebastien Cirou, Rene Reinbigler, Virginie Buisson, Jean-Louis Weissenbach
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Patent number: 9744487Abstract: The invention concerns a device comprising a base (2) and a door (20), said device having a closed door position in which a circuit (8) of the device comprises a bag comprising two flexible films and connectors of the conveying network, and a press (9) comprising a first she (16) disposed on a front face (5) of said base (2) and a second shed (17) disposed in said door (20); and a hinge system hinging said door (20) relative to said base (2), and disposed only on one side of said door (20) so as to form lateral clearances between said door (20) and said base (2) over the rest of a perimeter of said door (20).Type: GrantFiled: September 23, 2014Date of Patent: August 29, 2017Assignee: EMD Millipore CorporationInventors: Sebastien Cirou, Rene Reinbigler, Virginie Buisson, Jean-Louis Weissenbach
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Patent number: 9739424Abstract: The invention concerns a device comprising: a base (2); a moveable or removable door (20), said device having a closed door position; and in the closed door position, a circuit (8) comprising a bag comprising two flexible films and conveying network connectors, and a press (9) comprising a first shell (16) disposed on said front face (5) of said base (2) and a second shell (17) disposed in said door (20); said bag being clamped between said first shell (16) and said second shell (17) in a state in which conduits of said network for conveying liquid are formed between said films.Type: GrantFiled: September 23, 2014Date of Patent: August 22, 2017Assignee: EMD Millipore CorporationInventors: Sebastien Cirou, Rene Reinbigler, Virginie Buisson, Jean-Louis Weissenbach
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Patent number: 9676069Abstract: The invention concerns a filtration device comprising a manifold providing fluid connection and mechanical connection comprising a clamping plate movably mounted relative to the manifold and adapted to compress at least one cassette against the manifold, means for driving and guiding the clamping plate comprising a rod extending between the manifold and the plate, an actuator provided with a body and a member moveable relative to the body, which member is adapted to move through a predetermined travel between an extended position and a retracted position, the body being carried by the manifold, and the member carrying the rod and driving the plate via the rod to a clamped position in which the member is in an intermediate retracted position in which it has moved through a shorter travel than the predetermined travel relative to its extended position.Type: GrantFiled: June 23, 2014Date of Patent: June 13, 2017Assignee: EMD Millipore CorporationInventors: Sebastien Cirou, Jean-Louis Weissenbach, Rene Reinbigler, Jean-Luc Beulay, Frans Mels, Cecile Delbos
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Patent number: 9592577Abstract: The invention concerns a filtration device comprising a providing fluid connection and mechanical connection comprising a clamping plate movably mounted relative to the manifold and adapted to compress at least one cassette against the manifold, means for driving and guiding the clamping plate comprising a rod extending between the manifold and the plate, an actuator provided with a body and a member moveable relative to the body, which member is adapted to move through a predetermined travel between an extended position and a retracted position, the body being carried by the manifold, and the member carrying the rod and driving the plate via the rod to a clamped position in which the member is in an intermediate retracted position in which it has moved through a shorter travel than the predetermined travel relative to its extended position.Type: GrantFiled: June 23, 2014Date of Patent: March 14, 2017Assignee: EMD Millipore CorporationInventors: Sebastien Cirou, Jean-Louis Weissenbach, Rene Reinbigler, Jean-Luc Beulay, Frans Mels, Cecile Delbos
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Patent number: 9573230Abstract: The invention concerns a filtration device comprising a manifold providing fluid connection and mechanical connection comprising a clamping plate movably mounted relative to the manifold and adapted to compress at least one cassette against the manifold, means for driving and guiding the clamping plate comprising a rod extending between the manifold and the plate, an actuator provided with a body and a member moveable relative to the body, which member is adapted to move through a predetermined travel between an extended position and a retracted position, the body being carried by the manifold, and the member carrying the rod and driving the plate via the rod to a clamped position in which the member is in an intermediate retracted position in which it has moved through a shorter travel than the predetermined travel relative to its extended position.Type: GrantFiled: October 6, 2014Date of Patent: February 21, 2017Assignee: EMD Millipore CorporationInventors: Sebastien Cirou, Jean-Louis Weissenbach, Rene Reinbigler, Jean-Luc Beulay, Frans Mels, Cecile Delbos
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Patent number: 9528085Abstract: The method comprises the step of forming pipes (12) by clamping a bag between shells (13, 14) and by injecting an inflating agent via an inflating connector. The circuit comprises a bag (126) and a press (10) comprising two shells (13, 14) clamping said bag in a state in which pipes (12) are formed between the films (25, 26) of the bag.Type: GrantFiled: January 11, 2010Date of Patent: December 27, 2016Assignee: EMD Millipore CorporationInventors: Rene Reinbigler, Jean-Louis Weissenbach
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Patent number: 9523072Abstract: A circuit for biological liquid including a bag having two films and a press. The press includes two shells that clamp the bag in a state in which pipes are formed between the films of the bag.Type: GrantFiled: March 8, 2012Date of Patent: December 20, 2016Assignee: EMD Millipore CorporationInventors: Rene Reinbigler, Jean-Louis Weissenbach
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Publication number: 20160264923Abstract: The method comprises the step of forming pipes (12) by clamping a bag between shells (13, 14) and by injecting an inflating agent via an inflating connector. The circuit comprises a bag (126) and a press (10) comprising two shells (13, 14) clamping said bag in a state in which pipes (12) are formed between the films (25, 26) of the bag.Type: ApplicationFiled: May 23, 2016Publication date: September 15, 2016Inventors: Rene Reinbigler, Jean-Louis Weissenbach
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Patent number: 9259085Abstract: A device for supporting a plurality of flexible containers for liquid, including a plurality of baskets, each containing at least one of the flexible containers, a magazine to receive the baskets, able to adopt an operating configuration in which the baskets are disposed inclined one above the other, which magazine includes supports for the baskets, able to adopt a loading/unloading position such that each basket can be loaded/unloaded along a horizontal path, and able to adopt an operating position to maintain each basket in an inclined position to make the magazine adopt the operating configuration, and a driver for driving the supports between the loading/unloading position and the operating position.Type: GrantFiled: April 30, 2014Date of Patent: February 16, 2016Assignee: EMD Millipore CorporationInventors: Rene Reinbigler, Jean-Louis Weissenbach
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Patent number: 9205955Abstract: The invention concerns a device comprising a base; a circuit comprising a bag comprising two flexible films and conveying network connectors, and a press (9) comprising a first shell (16) disposed upright on a front face (5) of said base (2) and a second shell (17) mounted on said first shell (16), said first shell (16) and second shell (17) clamping said bag to form conduits; said bag comprising first through apertures on one side and said first shell (16) comprising hooking studs (106) on an upper part, which studs (106) pass through said first apertures.Type: GrantFiled: June 6, 2011Date of Patent: December 8, 2015Assignee: EMD Millipore CorporationInventors: Sebastien Cirou, Rene Reinbigler, Virginie Buisson, Jean-Louis Weissenbach