Patents by Inventor Rene Reinbigler

Rene Reinbigler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240010965
    Abstract: The present application relates to biotechnological fluid treating, such as biopharmaceutical liquids in order to obtain products such as monoclonal antibodies, vaccines or recombinant proteins, and particularly to a system for treating a biotechnical fluid, having a bioprocess machine and at least one bioprocess machine helper, configured to connect to each other and each comprising a controller, in turn comprising a machine-to-machine communication tool configured for connecting to a network.
    Type: Application
    Filed: August 19, 2021
    Publication date: January 11, 2024
    Applicant: MERCK PATENT GMBH
    Inventors: Rene REINBIGLER, Denis DUBRET, Steven MILLER
  • Publication number: 20230340395
    Abstract: The present application relates to biotechnological fluid treating, such as biopharmaceutical liquids in order to obtain products such as monoclonal antibodies, vaccines or recombinant proteins, and particularly to a system for treating a biotechnical fluid, having a bioprocess machine and at least one bioprocess machine helper, configured to connect to each other and each comprising a controller, in turn comprising a machine-to-machine communication tool configured for connecting to a network
    Type: Application
    Filed: August 19, 2021
    Publication date: October 26, 2023
    Applicant: MERCK PATENT GMBH
    Inventors: Rene REINBIGLER, Denis DUBRET, Steven MILLER
  • Publication number: 20230313114
    Abstract: The present application relates to biotechnological fluid treating, such as biopharmaceutical liquids in order to obtain products such as monoclonal antibodies, vaccines or recombinant proteins, and particularly to a system for treating a biotechnical fluid, having a bioprocess machine and at least one bioprocess machine helper, configured to connect to each other and each comprising a controller, in turn comprising a machine-to-machine communication tool configured for connecting to a network.
    Type: Application
    Filed: August 19, 2021
    Publication date: October 5, 2023
    Applicant: MERCK PATENT GMBH
    Inventors: Rene REINBIGLER, Denis DUBRET, Steve MILLER
  • Patent number: 11511281
    Abstract: A fluid transfer device includes a syringe barrel having a chamber, a first plunger slidably movable inside the chamber, and a second plunger slidably movable inside the chamber. The distal end portion of the first plunger is engageable with the proximal end portion of the second plunger such that when the distal end portion of the first plunger and the proximal end portion of the second plunger are engaged, the second plunger is movable by the first plunger. A check valve may be incorporated into the distal end portion of the second plunger to allow a fluid to pass therethrough in a direction towards the proximal end portion of the second plunger and prevent a fluid to pass therethrough in a reverse direction. A fluid transfer assembly and a sampling method are also described.
    Type: Grant
    Filed: May 19, 2020
    Date of Patent: November 29, 2022
    Assignee: EMD Millipore Corporation
    Inventors: Joseph Muldoon, Rene Reinbigler
  • Patent number: 10766666
    Abstract: The invention concerns a device comprising a base (2) and a door (20), said device having a closed door position in which a circuit (8) of the device comprises a bag comprising two flexible films and connectors of the conveying network, and a press (9) comprising a first shell (16) disposed on a front face (5) of said base (2) and a second shell (17) disposed in said door (20); and a hinge system hinging said door (20) relative to said base (2), and disposed only on one side of said door (20) so as to form lateral clearances between said door (20) and said base (2) over the rest of a perimeter of said door (20).
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: September 8, 2020
    Assignee: EMD Millipore Corporation
    Inventors: Sebastien Cirou, Rene Reinbigler, Virginie Buisson, Jean-Louis Weissenbach
  • Publication number: 20200276587
    Abstract: A fluid transfer device includes a syringe barrel having a chamber, a first plunger slidably movable inside the chamber, and a second plunger slidably movable inside the chamber. The distal end portion of the first plunger is engageable with the proximal end portion of the second plunger such that when the distal end portion of the first plunger and the proximal end portion of the second plunger are engaged, the second plunger is movable by the first plunger. A check valve may be incorporated into the distal end portion of the second plunger to allow a fluid to pass therethrough in a direction towards the proximal end portion of the second plunger and prevent a fluid to pass therethrough in a reverse direction. A fluid transfer assembly and a sampling method are also described.
    Type: Application
    Filed: May 19, 2020
    Publication date: September 3, 2020
    Inventors: Joseph Muldoon, Rene Reinbigler
  • Patent number: 10688495
    Abstract: A fluid transfer device includes a syringe barrel having a chamber, a first plunger slidably movable inside the chamber, and a second plunger slidably movable inside the chamber. The distal end portion of the first plunger is engageable with the proximal end portion of the second plunger such that when the distal end portion of the first plunger and the proximal end portion of the second plunger are engaged, the second plunger is movable by the first plunger. A check valve may be incorporated into the distal end portion of the second plunger to allow a fluid to pass therethrough in a direction towards the proximal end portion of the second plunger and prevent a fluid to pass therethrough in a reverse direction. A fluid transfer assembly and a sampling method are also described.
    Type: Grant
    Filed: October 14, 2015
    Date of Patent: June 23, 2020
    Assignee: EMD Millipore Corporation
    Inventors: Joseph Muldoon, Rene Reinbigler
  • Patent number: 10195605
    Abstract: The method comprises the step of forming pipes (12) by clamping a bag between shells (13, 14) and by injecting an inflating agent via an inflating connector. The circuit comprises a bag (126) and a press (10) comprising two shells (13, 14) clamping said bag in a state in which pipes (12) are formed between the films (25, 26) of the bag.
    Type: Grant
    Filed: May 23, 2016
    Date of Patent: February 5, 2019
    Assignee: EMD Millipore Corporation
    Inventors: Rene Reinbigler, Jean-Louis Weissenbach
  • Publication number: 20180214876
    Abstract: A fluid transfer device includes a syringe barrel having a chamber, a first plunger slidably movable inside the chamber, and a second plunger slidably movable inside the chamber. The distal end portion of the first plunger is engageable with the proximal end portion of the second plunger such that when the distal end portion of the first plunger and the proximal end portion of the second plunger are engaged, the second plunger is movable by the first plunger. A check valve may be incorporated into the distal end portion of the second plunger to allow a fluid to pass therethrough in a direction towards the proximal end portion of the second plunger and prevent a fluid to pass therethrough in a reverse direction. A fluid transfer assembly and a sampling method are also described.
    Type: Application
    Filed: October 14, 2015
    Publication date: August 2, 2018
    Inventors: Joseph Muldoon, Rene Reinbigler
  • Publication number: 20180111720
    Abstract: The invention concerns a device comprising a base (2) and a door (20), said device having a closed door position in which a circuit (8) of the device comprises a bag comprising two flexible films and connectors of the conveying network, and a press (9) comprising a first shell (16) disposed on a front face (5) of said base (2) and a second shell (17) disposed in said door (20); and a hinge system hinging said door (20) relative to said base (2), and disposed only on one side of said door (20) so as to form lateral clearances between said door (20) and said base (2) over the rest of a perimeter of said door (20).
    Type: Application
    Filed: December 20, 2017
    Publication date: April 26, 2018
    Inventors: Sebastien Cirou, Rene Reinbigler, Virginie Buisson, Jean-Louis Weissenbach
  • Patent number: 9744487
    Abstract: The invention concerns a device comprising a base (2) and a door (20), said device having a closed door position in which a circuit (8) of the device comprises a bag comprising two flexible films and connectors of the conveying network, and a press (9) comprising a first she (16) disposed on a front face (5) of said base (2) and a second shed (17) disposed in said door (20); and a hinge system hinging said door (20) relative to said base (2), and disposed only on one side of said door (20) so as to form lateral clearances between said door (20) and said base (2) over the rest of a perimeter of said door (20).
    Type: Grant
    Filed: September 23, 2014
    Date of Patent: August 29, 2017
    Assignee: EMD Millipore Corporation
    Inventors: Sebastien Cirou, Rene Reinbigler, Virginie Buisson, Jean-Louis Weissenbach
  • Patent number: 9739424
    Abstract: The invention concerns a device comprising: a base (2); a moveable or removable door (20), said device having a closed door position; and in the closed door position, a circuit (8) comprising a bag comprising two flexible films and conveying network connectors, and a press (9) comprising a first shell (16) disposed on said front face (5) of said base (2) and a second shell (17) disposed in said door (20); said bag being clamped between said first shell (16) and said second shell (17) in a state in which conduits of said network for conveying liquid are formed between said films.
    Type: Grant
    Filed: September 23, 2014
    Date of Patent: August 22, 2017
    Assignee: EMD Millipore Corporation
    Inventors: Sebastien Cirou, Rene Reinbigler, Virginie Buisson, Jean-Louis Weissenbach
  • Patent number: 9676069
    Abstract: The invention concerns a filtration device comprising a manifold providing fluid connection and mechanical connection comprising a clamping plate movably mounted relative to the manifold and adapted to compress at least one cassette against the manifold, means for driving and guiding the clamping plate comprising a rod extending between the manifold and the plate, an actuator provided with a body and a member moveable relative to the body, which member is adapted to move through a predetermined travel between an extended position and a retracted position, the body being carried by the manifold, and the member carrying the rod and driving the plate via the rod to a clamped position in which the member is in an intermediate retracted position in which it has moved through a shorter travel than the predetermined travel relative to its extended position.
    Type: Grant
    Filed: June 23, 2014
    Date of Patent: June 13, 2017
    Assignee: EMD Millipore Corporation
    Inventors: Sebastien Cirou, Jean-Louis Weissenbach, Rene Reinbigler, Jean-Luc Beulay, Frans Mels, Cecile Delbos
  • Patent number: 9592577
    Abstract: The invention concerns a filtration device comprising a providing fluid connection and mechanical connection comprising a clamping plate movably mounted relative to the manifold and adapted to compress at least one cassette against the manifold, means for driving and guiding the clamping plate comprising a rod extending between the manifold and the plate, an actuator provided with a body and a member moveable relative to the body, which member is adapted to move through a predetermined travel between an extended position and a retracted position, the body being carried by the manifold, and the member carrying the rod and driving the plate via the rod to a clamped position in which the member is in an intermediate retracted position in which it has moved through a shorter travel than the predetermined travel relative to its extended position.
    Type: Grant
    Filed: June 23, 2014
    Date of Patent: March 14, 2017
    Assignee: EMD Millipore Corporation
    Inventors: Sebastien Cirou, Jean-Louis Weissenbach, Rene Reinbigler, Jean-Luc Beulay, Frans Mels, Cecile Delbos
  • Patent number: 9573230
    Abstract: The invention concerns a filtration device comprising a manifold providing fluid connection and mechanical connection comprising a clamping plate movably mounted relative to the manifold and adapted to compress at least one cassette against the manifold, means for driving and guiding the clamping plate comprising a rod extending between the manifold and the plate, an actuator provided with a body and a member moveable relative to the body, which member is adapted to move through a predetermined travel between an extended position and a retracted position, the body being carried by the manifold, and the member carrying the rod and driving the plate via the rod to a clamped position in which the member is in an intermediate retracted position in which it has moved through a shorter travel than the predetermined travel relative to its extended position.
    Type: Grant
    Filed: October 6, 2014
    Date of Patent: February 21, 2017
    Assignee: EMD Millipore Corporation
    Inventors: Sebastien Cirou, Jean-Louis Weissenbach, Rene Reinbigler, Jean-Luc Beulay, Frans Mels, Cecile Delbos
  • Patent number: 9528085
    Abstract: The method comprises the step of forming pipes (12) by clamping a bag between shells (13, 14) and by injecting an inflating agent via an inflating connector. The circuit comprises a bag (126) and a press (10) comprising two shells (13, 14) clamping said bag in a state in which pipes (12) are formed between the films (25, 26) of the bag.
    Type: Grant
    Filed: January 11, 2010
    Date of Patent: December 27, 2016
    Assignee: EMD Millipore Corporation
    Inventors: Rene Reinbigler, Jean-Louis Weissenbach
  • Patent number: 9523072
    Abstract: A circuit for biological liquid including a bag having two films and a press. The press includes two shells that clamp the bag in a state in which pipes are formed between the films of the bag.
    Type: Grant
    Filed: March 8, 2012
    Date of Patent: December 20, 2016
    Assignee: EMD Millipore Corporation
    Inventors: Rene Reinbigler, Jean-Louis Weissenbach
  • Publication number: 20160264923
    Abstract: The method comprises the step of forming pipes (12) by clamping a bag between shells (13, 14) and by injecting an inflating agent via an inflating connector. The circuit comprises a bag (126) and a press (10) comprising two shells (13, 14) clamping said bag in a state in which pipes (12) are formed between the films (25, 26) of the bag.
    Type: Application
    Filed: May 23, 2016
    Publication date: September 15, 2016
    Inventors: Rene Reinbigler, Jean-Louis Weissenbach
  • Patent number: 9259085
    Abstract: A device for supporting a plurality of flexible containers for liquid, including a plurality of baskets, each containing at least one of the flexible containers, a magazine to receive the baskets, able to adopt an operating configuration in which the baskets are disposed inclined one above the other, which magazine includes supports for the baskets, able to adopt a loading/unloading position such that each basket can be loaded/unloaded along a horizontal path, and able to adopt an operating position to maintain each basket in an inclined position to make the magazine adopt the operating configuration, and a driver for driving the supports between the loading/unloading position and the operating position.
    Type: Grant
    Filed: April 30, 2014
    Date of Patent: February 16, 2016
    Assignee: EMD Millipore Corporation
    Inventors: Rene Reinbigler, Jean-Louis Weissenbach
  • Patent number: 9205955
    Abstract: The invention concerns a device comprising a base; a circuit comprising a bag comprising two flexible films and conveying network connectors, and a press (9) comprising a first shell (16) disposed upright on a front face (5) of said base (2) and a second shell (17) mounted on said first shell (16), said first shell (16) and second shell (17) clamping said bag to form conduits; said bag comprising first through apertures on one side and said first shell (16) comprising hooking studs (106) on an upper part, which studs (106) pass through said first apertures.
    Type: Grant
    Filed: June 6, 2011
    Date of Patent: December 8, 2015
    Assignee: EMD Millipore Corporation
    Inventors: Sebastien Cirou, Rene Reinbigler, Virginie Buisson, Jean-Louis Weissenbach