Patents by Inventor Rene Sit

Rene Sit has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYNTHETIC NUCLEIC ACID SPIKE-INS
    Publication number: 20240043923
    Abstract: This disclosure provides methods for determining relative abundance of one or more non-host species in a sample from a host. Also provided are methods involving addition of known concentrations of synthetic nucleic acids to a sample and performing sequencing assays to identify non-host species such as pathogens. Also provided are methods of tracking samples, tracking reagents, and tracking diversity loss in sequencing assays.
    Type: Application
    Filed: May 8, 2023
    Publication date: February 8, 2024
    Inventors: Fred C. Christians, Igor D. Vilfan, Michael Kertesz, Timothy A. Blauwkamp, Shivkumar Venkatasubrahmanyam, Michael Rosen, Rene Sit
  • Sample preparation methods, systems and compositions
    Patent number: 11834711
    Abstract: The disclosure provides methods, compositions, systems, and kits for the concurrent detection and analysis of different structural and chemical forms of nucleic acids in a sample.
    Type: Grant
    Filed: September 24, 2021
    Date of Patent: December 5, 2023
    Assignee: Karius, Inc.
    Inventors: Timothy A Blauwkamp, Rene Sit, Igor D. Vilfan
  • Synthetic nucleic acid spike-ins
    Patent number: 11692224
    Abstract: This disclosure provides methods for determining relative abundance of one or more non-host species in a sample from a host. Also provided are methods involving addition of known concentrations of synthetic nucleic acids to a sample and performing sequencing assays to identify non-host species such as pathogens. Also provided are methods of tracking samples, tracking reagents, and tracking diversity loss in sequencing assays.
    Type: Grant
    Filed: June 23, 2021
    Date of Patent: July 4, 2023
    Assignee: Karius, Inc.
    Inventors: Fred C. Christians, Igor D. Vilfan, Michael Kertesz, Timothy A. Blauwkamp, Shivkumar Venkatasubrahmanyam, Michael Rosen, Rene Sit
  • SAMPLE PREPARATION METHODS, SYSTEMS AND COMPOSITIONS
    Publication number: 20220186304
    Abstract: The disclosure provides methods, compositions, systems, and kits for the concurrent detection and analysis of different structural and chemical forms of nucleic acids in a sample.
    Type: Application
    Filed: September 24, 2021
    Publication date: June 16, 2022
    Inventors: Timothy A. BLAUWKAMP, Rene SIT, Igor D. VILFAN
  • Sample preparation methods, systems and compositions
    Patent number: 11180800
    Abstract: The disclosure provides methods, compositions, systems, and kits for the concurrent detection and analysis of different structural and chemical forms of nucleic acids in a sample.
    Type: Grant
    Filed: May 13, 2020
    Date of Patent: November 23, 2021
    Assignee: Karius, Inc.
    Inventors: Timothy A. Blauwkamp, Rene Sit, Igor D. Vilfan
  • SYNTHETIC NUCLEIC ACID SPIKE-INS
    Publication number: 20210324467
    Abstract: This disclosure provides methods for determining relative abundance of one or more non-host species in a sample from a host. Also provided are methods involving addition of known concentrations of synthetic nucleic acids to a sample and performing sequencing assays to identify non-host species such as pathogens. Also provided are methods of tracking samples, tracking reagents, and tracking diversity loss in sequencing assays.
    Type: Application
    Filed: June 23, 2021
    Publication date: October 21, 2021
    Inventors: Fred C. Christians, Igor D. Vilfan, Michael Kertesz, Timothy A. Blauwkamp, Shivkumar Venkatasubrahmanyam, Michael Rosen, Rene Sit
  • Synthetic nucleic acid spike-ins
    Patent number: 11078532
    Abstract: This disclosure provides methods for determining relative abundance of one or more non-host species in a sample from a host. Also provided are methods involving addition of known concentrations of synthetic nucleic acids to a sample and performing sequencing assays to identify non-host species such as pathogens. Also provided are methods of tracking samples, tracking reagents, and tracking diversity loss in sequencing assays.
    Type: Grant
    Filed: April 16, 2018
    Date of Patent: August 3, 2021
    Assignee: Karius, Inc.
    Inventors: Fred C. Christians, Igor D. Vilfan, Michael Kertesz, Timothy A. Blauwkamp, Shivkumar Venkatasubrahmanyam, Michael Rosen, Rene Sit
  • SAMPLE PREPARATION METHODS, SYSTEMS AND COMPOSITIONS
    Publication number: 20200399691
    Abstract: The disclosure provides methods, compositions, systems, and kits for the concurrent detection and analysis of different structural and chemical forms of nucleic acids in a sample.
    Type: Application
    Filed: May 13, 2020
    Publication date: December 24, 2020
    Inventors: Timothy A. BLAUWKAMP, Rene SIT, Igor D. VILFAN
  • Sample preparation methods, systems and compositions
    Patent number: 10697008
    Abstract: The disclosure provides methods, compositions, systems, and kits for the concurrent detection and analysis of different structural and chemical forms of nucleic acids in a sample.
    Type: Grant
    Filed: April 12, 2018
    Date of Patent: June 30, 2020
    Assignee: KARIUS, INC.
    Inventors: Timothy A. Blauwkamp, Rene Sit, Igor D. Vilfan
  • SAMPLE PREPARATION METHODS, SYSTEMS AND COMPOSITIONS
    Publication number: 20180371538
    Abstract: The disclosure provides methods, compositions, systems, and kits for the concurrent detection and analysis of different structural and chemical forms of nucleic acids in a sample.
    Type: Application
    Filed: April 12, 2018
    Publication date: December 27, 2018
    Inventors: Timothy A. Blauwkamp, Rene Sit, Igor D. Vilfan
  • SYNTHETIC NUCLEIC ACID SPIKE-INS
    Publication number: 20180237851
    Abstract: This disclosure provides methods for determining relative abundance of one or more non-host species in a sample from a host. Also provided are methods involving addition of known concentrations of synthetic nucleic acids to a sample and performing sequencing assays to identify non-host species such as pathogens. Also provided are methods of tracking samples, tracking reagents, and tracking diversity loss in sequencing assays.
    Type: Application
    Filed: April 16, 2018
    Publication date: August 23, 2018
    Inventors: Fred C. Christians, Igor D. Vilfan, Michael Kertesz, Timothy A. Blauwkamp, Shivkumar Venkatasubrahmanyam, Michael Rosen, Rene Sit
  • Synthetic nucleic acid spike-ins
    Patent number: 9976181
    Abstract: This disclosure provides methods for determining relative abundance of one or more non-host species in a sample from a host. Also provided are methods involving addition of known concentrations of synthetic nucleic acids to a sample and performing sequencing assays to identify non-host species such as pathogens. Also provided are methods of tracking samples, tracking reagents, and tracking diversity loss in sequencing assays.
    Type: Grant
    Filed: March 24, 2017
    Date of Patent: May 22, 2018
    Assignee: KARIUS, INC.
    Inventors: Fred C. Christians, Igor D. Vilfan, Michael Kertesz, Timothy A. Blauwkamp, Shivkumar Venkatasubrahmanyam, Michael Rosen, Rene Sit
  • SYNTHETIC NUCLEIC ACID SPIKE-INS
    Publication number: 20170275691
    Abstract: This disclosure provides methods for determining relative abundance of one or more non-host species in a sample from a host. Also provided are methods involving addition of known concentrations of synthetic nucleic acids to a sample and performing sequencing assays to identify non-host species such as pathogens. Also provided are methods of tracking samples, tracking reagents, and tracking diversity loss in sequencing assays.
    Type: Application
    Filed: March 24, 2017
    Publication date: September 28, 2017
    Inventors: Fred C. Christians, Igor D. Vilfan, Michael Kertesz, Timothy A. Blauwkamp, Shivkumar Venkatasubrahmanyam, Michael Rosen, Rene Sit