Patents by Inventor Rene Tolba

Rene Tolba has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATING POSTOPERATIVE MECHANICAL STRESS WITH AN ECTOINE
    Publication number: 20160106747
    Abstract: A method of treatment of a patient suffering from postoperative inflammatory stress and pain caused by mechanical impact exerted on portions of the body of the patient that causes damaged tissue wherein the inflammatory stress and pain of the operation outlast the healing of damaged tissue and which is not related to, or caused by, uncontrolled proteolysis. The treatment comprises administering a tetrahydropyrimidine selected from ectoine and/or hydroxyectoine to the patient.
    Type: Application
    Filed: December 28, 2015
    Publication date: April 21, 2016
    Applicant: Bitop AG
    Inventors: Rene Tolba, Gerhild van Echten-Deckert, Georg Lentzen, Andreas Bilstein
  • ORGAN STORAGE SOLUTION
    Publication number: 20150104781
    Abstract: The invention relates to a storage solution for the preservation of organs, tissue or organ systems to be transplanted, said solution being based on the known HTK, UW or Celsior solutions. In accordance with the invention it has been determined that ischemia and reperfusion injury could be reduced through the addition of ectoine or hydroxyectoine.
    Type: Application
    Filed: March 15, 2013
    Publication date: April 16, 2015
    Applicant: bitop AG
    Inventors: Andreas Bilstein, Georg Lentzen, Rene Tolba, Fabian Bernal Quesnel
  • Use of Tetrahydropyrimidines
    Publication number: 20140163053
    Abstract: A method of treatment of postoperative inflammatory stress and pain comprising administering a tetrahydropyrimidine selected from ectoine and/or hydroxyectoine to a patient in need of such treatment.
    Type: Application
    Filed: December 6, 2012
    Publication date: June 12, 2014
    Applicant: Bitop Aktiengesellschaft
    Inventors: Rene Tolba, Gerhild van Echten-Deckert, Georg Lentzen, Andress Bilstein
  • USE OF TETRAHYDROPYRIMIDINES
    Publication number: 20110269784
    Abstract: Tetrahydropyrimidines of the formula where R is a hydrogen atom or a hydrocarbon radical comprising up to eight carbon atoms, R? is hydrogen, OH or OR? and R? is R or COR, with R having the above described significance for use in the prevention or treatment of post-operative inflammatory stresses and pain.
    Type: Application
    Filed: January 30, 2009
    Publication date: November 3, 2011
    Inventors: Rene Tolba, Gerhild van Echten-Deckert, Georg Lentzen, Andreas Bilstein