Patents by Inventor Renee E. Bruno

Renee E. Bruno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR ISOLATION OF GENOMIC DNA, RNA AND PROTEINS FROM A SINGLE SAMPLE
    Publication number: 20120271042
    Abstract: The invention provides systems, methods and kits for the separation and/or purification of at least two cellular components selected from genomic DNA, RNA and proteins. The method includes first lysing a biological sample to generate an aqueous solution containing the cellular components; then applying the aqueous solution to a first mineral support under conditions for genomic DNA to bind; and collecting the flowthrough which contains unbound total RNA and proteins. The method further includes applying the flowthrough to a second mineral support under conditions for RNA to bind, and collecting the flowthrough which contains proteins. The genomic DNA and total RNA bound can be eluted while the protein in the flowthrough can be further purified. Further the total RNA isolated could be used to isolate small RNA such as microRNA.
    Type: Application
    Filed: June 28, 2012
    Publication date: October 25, 2012
    Applicant: GE HEALTHCARE BIO-SCIENCES CORP.
    Inventors: MIAO JIANG, MARK S. BRIGGS, ROHINI DHULIPALA, YUYANG CHRISTINE CAI, RENEE E. BRUNO
  • METHOD FOR ISOLATION OF GENOMIC DNA, RNA AND PROTEINS FROM A SINGLE SAMPLE
    Publication number: 20090143570
    Abstract: The invention provides systems, methods and kits for the separation and/or purification of at least two cellular components selected from genomic DNA, RNA and proteins. The method includes first lysing a biological sample to generate an aqueous solution containing the cellular components; then applying the aqueous solution to a first mineral support under conditions for genomic DNA to bind; and collecting the flowthrough which contains unbound total RNA and proteins. The method further includes applying the flowthrough to a second mineral support under conditions for RNA to bind, and collecting the flowthrough which contains proteins. The genomic DNA and total RNA bound can be eluted while the protein in the flowthrough can be further purified. Further the total RNA isolated could be used to isolate small RNA such as microRNA.
    Type: Application
    Filed: November 25, 2008
    Publication date: June 4, 2009
    Applicant: GE HEALTHCARE BIO-SCIENCES CORP.
    Inventors: Miao Jiang, Mark S. Briggs, Rohini Dhulipala, Yuyang Christine Cai, Renee E. Bruno