Patents by Inventor Renee M. Saville

Renee M. Saville has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220010268
    Abstract: The present disclosure provides methanotrophic bacteria that are modified to produce less glycogen, and methods of using the modified methanotrophic bacteria to produce a desired product, such as protein(s) or metabolite(s).
    Type: Application
    Filed: December 26, 2019
    Publication date: January 13, 2022
    Inventors: Renee M. Saville, Joshua A. Silverman, Vincent Tang, Eric G. Luning, Paloma Rueda, Megan Hsi, Yelena Stegantseva
  • Patent number: 11041159
    Abstract: The present disclosure provides nucleic acids and vectors for use with methanotrophic bacteria. Related host cells and methods for using such nucleic acids and vectors for expressing polypeptides or other genetic manipulation of methanotrophic bacteria are also provided.
    Type: Grant
    Filed: August 28, 2019
    Date of Patent: June 22, 2021
    Assignee: Calysta, Inc.
    Inventors: Renee M. Saville, Joshua Silverman, Jeremy Minshull, Jon Edward Ness, Effendi Leonard, Jana Stumpe, Mark Welch
  • Patent number: 10889842
    Abstract: The present disclosure relates to recombinant microorganisms engineered for enhance production of a desired amino acid, as well as related biomass, and compositions which are useful, inter alia, as animal feed ingredients. The present invention also provides related methods.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: January 12, 2021
    Assignee: CALYSTA, INC.
    Inventors: Renee M. Saville, Joshua A. Silverman, Eric G. Luning, Brandon D. Doss, Lorraine Joan Giver, Sol M. Resnick, Drew D. Regitsky
  • Publication number: 20200063146
    Abstract: The present disclosure provides nucleic acids and vectors for use with methanotrophic bacteria. Related host cells and methods for using such nucleic acids and vectors for expressing polypeptides or other genetic manipulation of methanotrophic bacteria are also provided.
    Type: Application
    Filed: August 28, 2019
    Publication date: February 27, 2020
    Inventors: Renee M. Saville, Joshua Silverman, Jeremy Minshull, Jon Edward Ness, Effendi Leonard, Jana Stumpe, Mark Welch
  • Patent number: 10450548
    Abstract: The present disclosure provides non-naturally occurring c1 microorganisms useful for the production of lactate and related compositions, as well as methods for the biologically production of lactate. In specific embodiments, the present disclosure provides non-naturally occurring methanotrophic bacteria which are useful for producing lactate from c1 substrates.
    Type: Grant
    Filed: June 18, 2014
    Date of Patent: October 22, 2019
    Assignee: CALYSTA, INC.
    Inventors: Renee M. Saville, Sungwon Lee, Drew D. Regitsky, Sol M. Resnick, Joshua A. Silverman
  • Patent number: 10443060
    Abstract: The present disclosure provides nucleic acids and vectors for use with methanotrophic bacteria. Related host cells and methods for using such nucleic acids and vectors for expressing polypeptides or other genetic manipulation of methanotrophic bacteria are also provided. In one aspect, the present disclosure is directed to a non-naturally occurring nucleic acid molecule, comprising (1) a promoter that is functional in a methanotrophic bacterium, and (2) a native or altered methanol dehydrogenase (MDH) ribosomal binding sequence, provided that when the promoter is an MDH gene promoter, the nucleic acid comprises an altered MDH ribosomal binding sequence.
    Type: Grant
    Filed: June 18, 2015
    Date of Patent: October 15, 2019
    Assignee: CALYSTA, INC.
    Inventors: Renee M. Saville, Joshua Silverman, Jeremy Minshull, Jon Edward Ness, Effendi Leonard, Jana Stumpe, Mark Welch
  • Publication number: 20190271019
    Abstract: The present disclosure relates to recombinant microorganisms engineered for enhanced production of a desired carbohydrate, as well as related biomass, and compositions which are useful, inter alia, as animal feed ingredients. The present disclosure also provides related methods.
    Type: Application
    Filed: May 15, 2019
    Publication date: September 5, 2019
    Inventors: Joshua A. Silverman, Lorraine Joan Giver, Jana Mueller, Renee M. Saville, Drew D. Regitsky
  • Patent number: 10337043
    Abstract: The present disclosure relates to recombinant microorganisms engineered for enhanced production of a desired carbohydrate, as well as related biomass, and compositions which are useful, inter alia, as animal feed ingredients. The present disclosure also provides related methods.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: July 2, 2019
    Assignee: CALYSTA, INC.
    Inventors: Joshua A. Silverman, Lorraine Joan Giver, Jana Mueller, Renee M. Saville, Drew D. Regitsky
  • Patent number: 10190123
    Abstract: The present disclosure relates to genetically engineered methanotrophic bacteria with the capability of growing on a multi-carbon substrate (e.g., glucose) as a primary or sole carbon source and methods for growing methanotrophic bacteria on the multi-carbon substrate.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: January 29, 2019
    Assignee: CALYSTA, INC.
    Inventors: Joshua A. Silverman, Effendi Leonard, Renee M. Saville
  • Publication number: 20180251800
    Abstract: The present disclosure relates to bioengineering approaches for producing biofuel and, in particular, to the use of a C1 metabolizing microorganism reactor system for converting C1 substrates, such as methane or methanol, into biomass and subsequently into biofuels, bioplastics, or the like.
    Type: Application
    Filed: January 29, 2018
    Publication date: September 6, 2018
    Inventors: Joshua A. Silverman, Sol M. Resnick, Michael Mendez, Renee M. Saville, Sungwon Lee, Luan Nguyen
  • Patent number: 10011840
    Abstract: The present disclosure relates to genetically engineered methanotrophic bacteria with the capability of growing on a multi-carbon substrate (e.g., glycerol) as a primary or sole carbon source and methods for growing methanotrophic bacteria on the multi-carbon substrate.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: July 3, 2018
    Assignee: CALYSTA, INC.
    Inventors: Joshua A. Silverman, Effendi Leonard, Renee M. Saville
  • Publication number: 20180112224
    Abstract: The present disclosure relates to genetically engineered methanotrophic bacteria with the capability of growing on a multi-carbon substrate (e.g., glucose) as a primary or sole carbon source and methods for growing methanotrophic bacteria on the multi-carbon substrate.
    Type: Application
    Filed: November 22, 2017
    Publication date: April 26, 2018
    Inventors: Joshua A. SILVERMAN, Effendi LEONARD, Renee M. SAVILLE
  • Publication number: 20180087059
    Abstract: The present disclosure relates to genetically engineered methanotrophic bacteria with the capability of growing on a multi-carbon substrate (e.g., glycerol) as a primary or sole carbon source and methods for growing methanotrophic bacteria on the multi-carbon substrate.
    Type: Application
    Filed: December 6, 2017
    Publication date: March 29, 2018
    Inventors: Joshua A. SILVERMAN, Effendi LEONARD, Renee M. SAVILLE
  • Patent number: 9845474
    Abstract: The present disclosure relates to genetically engineered methanotrophic bacteria with the capability of growing on a multi-carbon substrate as a primary or sole carbon source and methods for growing methanotrophic bacteria on a multi-carbon substrate.
    Type: Grant
    Filed: October 24, 2013
    Date of Patent: December 19, 2017
    Assignee: Calysta, Inc.
    Inventors: Joshua A. Silverman, Effendi Leonard, Renee M. Saville
  • Publication number: 20170121718
    Abstract: The present disclosure provides nucleic acids and vectors for use with methanotrophic bacteria. Related host cells and methods for using such nucleic acids and vectors for expressing polypeptides or other genetic manipulation of methanotrophic bacteria are also provided. In one aspect, the present disclosure is directed to a non-naturally occurring nucleic acid molecule, comprising (1) a promoter that is functional in a methanotrophic bacterium, and (2) a native or altered methanol dehydrogenase (MDH) ribosomal binding sequence, provided that when the promoter is an MDH gene promoter, the nucleic acid comprises an altered MDH ribosomal binding sequence.
    Type: Application
    Filed: June 18, 2015
    Publication date: May 4, 2017
    Inventors: Renee M. Saville, Joshua Silverman, Jeremy Minshull, Jon Edward Ness, Effendi Leonard, Jana Stumpe, Mark Welch
  • Publication number: 20160369246
    Abstract: The present disclosure provides non-naturally occurring c1 microorganisms useful for the production of lactate and related compositions, as well as methods for the biologically production of lactate. In specific embodiments, the present disclosure provides non-naturally occurring methanotrophic bacteria which are useful for producing lactate from c1 substrates.
    Type: Application
    Filed: June 18, 2014
    Publication date: December 22, 2016
    Inventors: Renee M. Saville, Sungwon Lee, Drew D. Regitsky, Sol M. Resnick, Joshua A. Silverman
  • Publication number: 20160333384
    Abstract: The present disclosure relates to recombinant microorganisms engineered for enhanced production of a desired carbohydrate, as well as related biomass, and compositions which are useful, inter alia, as animal feed ingredients. The present disclosure also provides related methods.
    Type: Application
    Filed: January 16, 2015
    Publication date: November 17, 2016
    Inventors: Joshua A. Silverman, Lorraine Joan Giver, Jana Mueller, Renee M. Saville, Drew D. Regitsky
  • Publication number: 20160289714
    Abstract: The present disclosure relates to bioengineering approaches for producing biofuel and, in particular, to the use of a C1 metabolizing microorganism reactor system for converting C1 substrates, such as methane or methanol, into biomass and subsequently into biofuels, bioplastics, or the like.
    Type: Application
    Filed: June 20, 2016
    Publication date: October 6, 2016
    Inventors: Joshua A. Silverman, Sol M. Resnick, Michael Mendez, Renee M. Saville, Sungwon Lee, Luan Nguyen
  • Publication number: 20160289782
    Abstract: The present disclosure relates to bioengineering approaches for producing biofuel and, in particular, to the use of a C1 metabolizing microorganism reactor system for converting C1 substrates, such as methane or methanol, into biomass and subsequently into biofuels, bioplastics, or the like.
    Type: Application
    Filed: June 20, 2016
    Publication date: October 6, 2016
    Inventors: Joshua A. Silverman, Sol M. Resnick, Michael Mendez, Renee M. Saville, Sungwon Lee, Luan Nguyen
  • Patent number: 9410168
    Abstract: The present disclosure relates to bioengineering approaches for producing biofuel and, in particular, to the use of a C1 metabolizing microorganism reactor system for converting C1 substrates, such as methane or methanol, into biomass and subsequently into biofuels, bioplastics, or the like.
    Type: Grant
    Filed: July 30, 2015
    Date of Patent: August 9, 2016
    Assignee: Calysta, Inc.
    Inventors: Joshua A. Silverman, Sol M. Resnick, Michael Mendez, Renee M. Saville, Sungwon Lee, Luan Nguyen