Patents by Inventor Renee Weber

Renee Weber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and arrangement for calibrating a sensor element
    Patent number: 10081831
    Abstract: A method is disclosed for calibrating a sensor element, which has an immobilized probe oligonucleotide, via which the bonding of a target nucleic acid (Z) can be detected by the sensor. In at least one embodiment, the method includes: a) bringing the sensor element into contact with a control nucleic acid (K), the melting temperature Tm(K) of which is less than the melting temperature Tm(Z) of the target nucleic acid (Z); b) hybridizing the control nucleic acid (K) to the probe oligonucleotide at a temperature T[p]<Tm(K), and detecting a positive control signal; and optionally c) modifying the stringent conditions such that T[n]>Tm(K) and detecting a negative control signal at a temperature T[n]. According to a refinement of at least one embodiment of the invention, a measuring signal of the target nucleic acid (Z) is measured at a measuring temperature T [mess], where Tm(K)<T[mess]<Tm(Z). The method is suited in particular for the calibration and quality control of microarrays.
    Type: Grant
    Filed: October 29, 2008
    Date of Patent: September 25, 2018
    Assignee: Boehringer Ingelheim Vetmedica GmbH
    Inventors: Katja Friedrich, Walter Gumbrecht, Peter Paulicka, Manfred Stanzel, Renee Weber
  • NATURALLY OCCURRING AUTOANTIBODIES AGAINST ALPHA-SYNUCLEIN THAT INHIBIT THE AGGREGATION AND CYTOTOXICITY OF ALPHA-SYNUCLEIN
    Publication number: 20140377271
    Abstract: The present invention refers to human antibodies which are directed against ?-Synuclein (?-Syn) and their use in medicine and diagnosis.
    Type: Application
    Filed: April 18, 2014
    Publication date: December 25, 2014
    Applicant: Dr. Rentschler Holding GmbH & Co. KG
    Inventors: Richard DODEL, Michael BACHER, Daniela BESONG AGBO, Sascha HAGEMANN, Monika BALZER-GELDSETZER, Bernd REHBERGER, Renee WEBER
  • Naturally occurring autoantibodies against alpha-synuclein that inhibit the aggregation and cytotoxicity of alpha-synuclein
    Patent number: 8741293
    Abstract: The present invention refers to human antibodies which are directed against ?-Synuclein (?-Syn) and their use in medicine and diagnosis.
    Type: Grant
    Filed: March 3, 2011
    Date of Patent: June 3, 2014
    Assignee: Dr. Rentschler Holding GmbH & Co. KG
    Inventors: Richard Dodel, Michael Bacher, Daniela Besong Agbo, Sascha Hagemann, Monika Balzer-Geldsetzer, Bernd Rehberger, Renee Weber
  • NATURALLY OCCURRING AUTOANTIBODIES AGAINST ALPHA-SYNUCLEIN THAT INHIBIT THE AGGREGATION AND CYTOTOXICITY OF ALPHA-SYNUCLEIN
    Publication number: 20130052200
    Abstract: The present invention refers to human antibodies which are directed against ?-Synuclein (?-Syn) and their use in medicine and diagnosis.
    Type: Application
    Filed: March 3, 2011
    Publication date: February 28, 2013
    Applicant: DR. RENTSCHLER HOLDING GMBH & CO. KG
    Inventors: Richard Dodel, Michael Bacher, Daniela Besong Agbo, Sascha Hagemann, Monika Balzer-Geldsetzer, Bernd Rehberger, Renee Weber
  • METHOD AND ARRANGEMENT FOR CALIBRATING A SENSOR ELEMENT
    Publication number: 20100248243
    Abstract: A method is disclosed for calibrating a sensor element, which has an immobilized probe oligonucleotide, via which the bonding of a target nucleic acid (Z) can be detected by the sensor. In at least one embodiment, the method includes: a) bringing the sensor element into contact with a control nucleic acid (K), the melting temperature Tm(K) of which is less than the melting temperature Tm(Z) of the target nucleic acid (Z); b) hybridizing the control nucleic acid (K) to the probe oligonucleotide at a temperature T[p]<Tm(K), and detecting a positive control signal; and optionally c) modifying the stringent conditions such that T[n]>Tm(K) and detecting a negative control signal at a temperature T[n]. According to a refinement of at least one embodiment of the invention, a measuring signal of the target nucleic acid (Z) is measured at a measuring temperature T [mess], where Tm(K)<T[mess]<Tm(Z). The method is suited in particular for the calibration and quality control of microarrays.
    Type: Application
    Filed: October 29, 2008
    Publication date: September 30, 2010
    Inventors: Katja Friedrich, Walter Gumbrecht, Peter Paulicka, Manfred Stanzel, Renee Weber